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The hydrogen bond (H bond) is one of the most important interactions that form the foundation of secondary and tertiary protein structure. Beyond holding protein structures together, H bonds are also intimately involved in solvent coordination, ligand binding, and enzyme catalysis. The H bond by definition involves the light atom, H, and it is very difficult to study directly, especially with X-ra

The extent to which male birds in polygynous species with biparental care assist in nestling feeding often varies considerably between nests of different mating status. Both how much polygynous males assist and how they divide their effort between nests may have a profound effect on the evolution of mating systems. In this study we investigated how males in the facultatively polygynous European st

Viktor Yushchenko’s 2010 designation of Stepan Bandera, the war‐time leader of the most radical and violent branch of the Ukrainian far right, as a national hero constituted, in many ways, the climax of the third post‐Soviet Ukrainian president’s instrumentalization of history. Yushchenko’s political use of history triggered sharply polarized, and often emotional discussions of Bandera’s role in h

The Quality of Life in Hand Eczema Questionnaire (QOLHEQ) is the only instrument assessing disease-specific health-related quality of life in patients with hand eczema. It is available in eight language versions. In this study we assessed if the items of different language versions of the QOLHEQ yield comparable values across countries. An international multicenter study was conducted with partici

Hepcidin is the main regulator of iron homeostasis and dysregulation of proteins involved in iron metabolism has been associated with tumorogenesis. However, to date, no epidemiological study has researched the association between hepcidin levels and gastric cancer risk. To further investigate the relationship between hepcidin levels and gastric cancer risk, we conducted a nested case-control stud

IMPaCT is a five-year project funded by the Department of Health, UK. Running in the UK and now Sweden, the IMPACT Project aims to target the poor physical health and excessive substance use seen in people with SMI. There is evidence that behavioural interventions may be associated with an improvement in physical health and substance use in this population. IMPaCT is a randomised controlled trial

In this paper, we consider positioning with observed-time-difference-of-arrival (OTDOA) for a device deployed in long-term-evolution (LTE) based narrow-band Internet-of-things (NB-IoT) systems. We propose an iterative expectation- maximization based successive interference cancellation (EM-SIC) algorithm to jointly consider estimations of residual frequency- offset (FO), fading-channel taps and ti

Gonadotropin-releasing hormone (GnRH), follicle-stimulating hormone, and luteinizing hormone orchestrate the reproduction cycle and regulate the sex steroid secretion from the gonads. In mammals, GnRH1 is secreted as a hormone from the hypothalamus, whereas both GnRH1 and GnRH2 are present as neurotransmitters/peptides in various tissues, where the peptides exert many different effects. mRNA codin

Objectives. Pulmonary hypertension (PH) is a serious condition where diagnosis often is delayed due to unspecific symptoms. New methods to diagnose and differentiate PH earlier would therefore be of great value. The aim of this study was therefore to evaluate the relationship between circulating angiogenic and inflammatory biomarkers and various hemodynamic variables in relation to different cause

The aim of this study is to explore the possibility of identifying speaker stance in discourse, provide an analytical resource for it and an evaluation of the level of agreement across speakers in the area of stance-taking in discourse. We explore to what extent language users agree about what kind of stances are expressed in natural language use or whether their interpretations diverge. In order

The normative implications of sustainable development mean that different understandings of how sustainability should be achieved will either facilitate or put at risk different values associated with economic, environmental and social aspects of sustainability. By a qualitative analysis of Swedish fishery legislation documents, we analyse and outline the consequences of two different and competin

We trace the social networks around Chinese entrepreneurs back to their firm's founding to learn about the role early events play in the later success of a business. We use name generator questions paired with career history questions to identify ‘event contacts’ missed by the usual focus on current business. We draw four conclusions from interviews with a large, stratified random sample of entrep

Using the wage accounts of two different farms in the 1830s and 1840s, matched with census records to determine the age of the workers, this article estimates age-wage profiles for male and female agricultural labourers. Females earned less than males, and had less wage growth over their life cycles. Male wage profiles peaked at age 30–5, earlier than the wage profiles of workers today. Before the

Cloud computing technology provides the means to share physical resources among multiple users and data center tenants by exposing them as virtual resources. There is a strong industrial drive to use similar technology and concepts to provide timing sensitive services. One such domain is a chain of connected virtual network functions. This allows the capacity of each function to be scaled up and d

Background: Toothpastes have widespread use in the population, and contain flavours to give a pleasant and often minty aroma. Flavours are prevalent allergens in toothpastes, and adverse reactions often present as perioral dermatitis or stomatitis. l-Carvone, a mint flavour found in spearmint oil, is one of these allergens. There are few studies on contact allergy to l-carvone, and some of them ha