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A rapid decarbonisation of the energy sector is key for mitigating climate change and in this transformation a transition to renewable heating is essential. To date, most attention in both research and policy on decarbonisation has been on electricity and transport systems, with less interest in the heating system. Half of the EU’s final energy consumption is made up by the heating and cooling sec
The current concept of social resilience, which developed from the classic definition of resilience, neglects social resilience as a social phenomenon including social experiences and practices in the face of change and adversity. I argue that framing social resilience as a capacity or ability undermines its characteristics as a complex and contextualized social phenomenon that contributes to adap
Grounded in social exchange theory (SET) this paper presents research on non-collaborative behaviour among accommodation businesses within their spatial context. The study adopts semi-structured interviews of 14 co-located accommodation businesses in Christchurch, New Zealand. The findings reveal three categories of non-collaborative factors that influence business behaviour, namely (1) resource-b
Cells are exposed to several types of integrin stimuli, which generate responses generally referred to as "integrin signals", but the specific responses to different integrin stimuli are poorly defined. In this study, signals induced by integrin ligation during cell attachment, mechanical force from intracellular contraction, or cell stretching by external force were compared. The elevated phospho
Amongst the many spectacular properties of hybrid lead halide perovskites, their defect tolerance is regarded as the key enabler for a spectrum of high-performance optoelectronic devices that propel perovskites to prominence. However, the plateauing efficiency enhancement of perovskite devices calls into question the extent of this defect tolerance in perovskite systems; an opportunity for perovsk
Huntington’s disease is a fatal neurodegenerative disorder caused by an expanded CAG triplet repeat in the huntingtin (HTT) gene. Previous research focused on neuropathology in the striatum and its association with a typical movement disorder. Direct effects of mutant HTT (mHTT) in the striatum may cause neuropathology, although non-cell autonomous effects have also been suggested. Important non-m
Ageism is a social problem that has harmful effects on the wellbeing of older people and needs to be tackled. It is pervasive and evident in the media (e.g., films, television, print and social media). Despite the fact that non-individual actors have adopted social media on a large scale in contemporary society, the social media representation of older people generated by those actors has remained
All bats possess eyes that are of adaptive value. Echolocating bats have retinae dominated by rod photoreceptors and use dim light vision for navigation, and in rare cases for hunting. However, the visual detection threshold of insectivorous echolocating bats remains unknown. Here, we determined this threshold for the vespertilionid bat Myotis daubentonii. We show that for a green luminous target,
Meshless methods are numerical methods that have the advantage of high accuracy without the need of an explicitly described mesh topology. In this class of methods, the Radial Point Interpolation Method (RPIM) is a promising collocation method where the application of radial basis functions yields high interpolation accuracy for even strongly unstructured node distributions. For electromagnetic si
Background Abdominal aortic aneurysm (AAA) is a vascular disease with a mortality rate of >80% if ruptured. Mitochondrial dysfunction has been previously implicated in AAA pathogenesis. In this study, we aimed to characterize the mitochondrial genetic landscape in AAA. Methods and Results Whole mitochondrial genome sequencing and bioinformatics analysis were performed in comorbidity matched 48 cas
Growing preclinical and clinical evidence highlights neurosteroid pathway imbalances in Parkinson's Disease (PD) and L-DOPA-induced dyskinesias (LIDs). We recently reported that 5α-reductase (5AR) inhibitors dampen dyskinesias in parkinsonian rats; however, unraveling which specific neurosteroid mediates this effect is critical to optimize a targeted therapy. Among the 5AR-related neurosteroids, s
It has been known for decades that risk factors for diabetes and cardiovascular disease (CVD) tend to cluster. Metabolic syndrome refers to this risk factor clustering for some of the more well-established and dangerous risk factors. This chapter provides a historical overview on the concept of the metabolic syndrome; describes the clinical criteria used in the definition of the metabolic syndrome
A number of field techniques were assessed on their reliability for estimating vegetation cover in Australian rangelands. The field sampling was undertaken using visual estimation, line intercepts, a crown cover model, and images acquired from a digital camera. The results from these methods were compared and analysed. The data obtained from these differing methods agree with each other in relativ
This article examines how the automation of jobs has shaped spatial patterns of intergenerational income mobility in the United States over the past three decades. Using data on the spread of industrial robots across 722 local labor markets, we find significantly lower rates of upward mobility in areas more exposed to automation. The erosion of mobility chances is rooted in childhood environments
We report on THz time-domain spectroscopy measurements of flux grown KTiOPO4 in the frequency range 0.6–7.0 THz (20 to 240 cm−1). Our results compare well with earlier Raman and far-infrared measurements. We theorize that the differences between the optical phonon mode resonances reported in the literature are due to what growth parameters and melt compositions are used to grow the crystals. We al
Epithelial ovarian cancer (EOC) is the fourth most common gynecologic cancer in Europe and is the leading cause of death among women with gynecologic malignancies. This is due to the fact that the majority of the patients are diagnosed with advanced stage disease. In these stages, extensive intraperitoneal metastases are often present, making therapy more difficult. The current standard treatment
