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Remissvar belastningsregister
Remissvar belastningsregister | Sveriges akademikers centralorganisation Hoppa till huvudinnehåll till startsida Öppna sökruta Öppna Huvudmeny Sök på saco.se Om Saco Kontakt Anställda hos Saco Saco studentråd Sacos styrelse Sacos revisorer Sacos organisation Sacos styrelse Kontaktuppgifter Sacos styrelse Verksamhetsberättelse och årsredovisning Federationen och förbunden Medlemsstatistik Förbunden
Systematic review and meta-analysis of humoral immunity proteins and mortality in sepsis
Purpose: Humoral immunity proteins—immunoglobulins, complement proteins, and antimicrobial peptides—have key antimicrobial and immunomodulatory functions in sepsis. We hypothesised that their circulating levels are lower in non-survivors, potentially resulting in impaired bacterial clearance and persistent or recurrent infections. Methods: We performed a systematic review and meta-analysis evaluat
Organisation of paediatric echocardiography laboratories and governance of echocardiography services and training in Europe : current status, disparities, and potential solutions. A survey from the Association for European Paediatric and Congenital Cardiology (AEPC) imaging working group
Background: There is limited data on the organisation of paediatric echocardiography laboratories in Europe. Methods: A structured and approved questionnaire was circulated across all 95 Association for European Paediatric and Congenital Cardiology affiliated centres. The aims were to evaluate: (1) facilities in paediatric echocardiography laboratories across Europe, (2) accredited laboratories, (
Lysates of Methylococcus capsulatus Bath induce a lean-like microbiota, intestinal FoxP3+RORγt+IL-17+ Tregs and improve metabolism
Interactions between host and gut microbial communities are modulated by diets and play pivotal roles in immunological homeostasis and health. We show that exchanging the protein source in a high fat, high sugar, westernized diet from casein to whole-cell lysates of the non-commensal bacterium Methylococcus capsulatus Bath is sufficient to reverse western diet-induced changes in the gut microbiota
RNA sequencing-based single sample predictors of molecular subtype and risk of recurrence for clinical assessment of early-stage breast cancer
Multigene assays for molecular subtypes and biomarkers can aid management of early invasive breast cancer. Using RNA-sequencing we aimed to develop single-sample predictor (SSP) models for clinical markers, subtypes, and risk of recurrence (ROR). A cohort of 7743 patients was divided into training and test set. We trained SSPs for subtypes and ROR assigned by nearest-centroid (NC) methods and SSPs
Sequence variants influencing the regulation of serum IgG subclass levels
Immunoglobulin G (IgG) is the main isotype of antibody in human blood. IgG consists of four subclasses (IgG1 to IgG4), encoded by separate constant region genes within the Ig heavy chain locus (IGH). Here, we report a genome-wide association study on blood IgG subclass levels. Across 4334 adults and 4571 individuals under 18 years, we discover ten new and identify four known variants at five loci
Myeloid Kdm6b deficiency results in advanced atherosclerosis
BACKGROUND AND AIMS: Atherosclerosis is a lipid-driven chronic inflammatory disorder of the arteries, and monocytes and macrophages play a central role in this process. Within the atherosclerotic lesion, macrophages can scavenge modified lipids and become the so-called foam cells. We previously reported that the epigenetic enzyme Kdm6b (also known as Jmjd3) controls the pro-fibrotic transcriptiona
Identification of sequence variants influencing immunoglobulin levels
Immunoglobulins are the effector molecules of the adaptive humoral immune system. In a genome-wide association study of 19,219 individuals, we found 38 new variants and replicated 5 known variants associating with IgA, IgG or IgM levels or with composite immunoglobulin traits, accounted for by 32 loci. Variants at these loci also affect the risk of autoimmune diseases and blood malignancies and in
The pTalpha promoter and enhancer are direct targets for transactivation by E box-binding proteins.
The pre-Talpha (pTalpha[?]) gene encodes a protein that forms the pre-TCR together with the newly expressed TCR beta chain during a defined stage of early T cell development. The restricted expression of this gene has been suggested to depend on a promoter and an enhancer element containing E boxes, which are potential binding sites for basic helix-loop-helix (bHLH) proteins. We here report that i
Localized exocytosis of primary (lysosomal) granules during phagocytosis: role of Ca2+-dependent tyrosine phosphorylation and microtubules.
The uptake and killing of bacteria by human neutrophils are dependent on the fusion of secretory granules with forming phagosomes. The earliest component of exocytosis was found to precede phagosome closure, so that granular membrane constituents were detectable on the plasmalemma. We show that during phagocytosis of IgG-opsonized particles, this early secretory response is highly polarized in the
Highlights of the São Paulo ISEV workshop on extracellular vesicles in cross-kingdom communication
In the past years, extracellular vesicles (EVs) have become an important field of research since EVs have been found to play a central role in biological processes. In pathogens, EVs are involved in several events during the host–pathogen interaction, including invasion, immunomodulation, and pathology as well as parasite–parasite communication. In this report, we summarised the role of EVs in inf
Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation
The onset of inflammation is associated with reactive oxygen species and oxidative damage to macromolecules like 7,8-dihydro-8-oxoguanine (8-oxoG) in DNA. Because 8-oxoguanine DNA glycosylase 1 (OGG1) binds 8-oxoG and because Ogg1-deficient mice are resistant to acute and systemic inflammation, we hypothesized that OGG1 inhibition may represent a strategy for the prevention and treatment of inflam
Rättighetslistan - Lunds universitets studenters rättigheter och ansvar
Rättighetslistan - Lunds universitets studenters rättigheter och ansvar Rättighetslistan - Lunds universitets studenters rättigheter och ansvar FASTSTÄLLD AV REKTOR 2020-09-10 Dnr STYR 2017/249 2 Rättighetslistan - Lunds universitets studenters rättigheter och ansvar är beslutad av rektor och ska fungera som stöd för studenterna, institutionerna, fakulteterna och studentkårerna för att klargöra va
https://www.ht.lu.se/fileadmin/user_upload/ht/dokument/Fakulteterna/Jamstalld/Rattighetslistan-2021-03_PDF.pdf - 2026-06-06
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Postadress Box 192, 221 00 LUND Besöksadress LUX, Helgonavägen 3, LUND Telefon 046-222 90 47 E-post martin.nykvist@kansliht.lu.se Webbadress http://www.ht.lu.se Fakul te tss tyre lsens arbe tsutskot t Uppföljning av humanistiska och teologiska fakulteternas kvalitetsdialoger för utbildning på grundnivå och avancerad nivå 2021 I mars månad varje år genomför HT-fakulteterna kvalitetsdialoger1 med in
Hon vill bryta tystnaden kring förlossningsskador
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https://www.design.lth.se/article/hon-vill-bryta-tystnaden-kring-foerlossningsskador/ - 2026-06-06
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Postal address Box 117, 221 00 Lund Visiting address LUX, Bldg. B, Helgonavägen 3 Telephone +46 46 222 83 15 Email kristina.arnrup_thorsbro@kansliht.lu.se Website www.ht.lu.se Facul ty Board ’s work ing commit tee General syllabus for third-cycle studies for the Degree of Doctor in Archaeology This syllabus was approved by the Board of the Joint Faculties of Humanities and Theology on 16 February
https://www.ht.lu.se/fileadmin/user_upload/ht/filserver/doktorand/studieplaner-engelska-2023/Archaeology.pdf - 2026-06-06
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Postal address Box 117, 221 00 Lund Visiting address LUX, Bldg. B, Helgonavägen 3 Telephone +46 46 222 83 15 Email kristina.arnrup_thorsbro@kansliht.lu.se Website www.ht.lu.se Facul ty Board ’s work ing commit tee General syllabus for third-cycle studies for the Degree of Doctor in Book History This syllabus was approved by the Board of the Joint Faculties of Humanities and Theology on 16 February
https://www.ht.lu.se/fileadmin/user_upload/ht/filserver/doktorand/studieplaner-engelska-2023/Book_history.pdf - 2026-06-06
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Postal address Box 117, 221 00 Lund Visiting address LUX, Bldg. B, Helgonavägen 3 Telephone +46 46 222 83 15 Email kristina.arnrup_thorsbro@kansliht.lu.se Website www.ht.lu.se Facul ty Board ’s work ing commit tee General syllabus for third-cycle studies for the Degree of Doctor in Church History This syllabus was approved by the Board of the Joint Faculties of Humanities and Theology on 16 Februa
https://www.ht.lu.se/fileadmin/user_upload/ht/filserver/doktorand/studieplaner-engelska-2023/Church_history.pdf - 2026-06-06
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Postal address Box 117, 221 00 Lund Visiting address LUX, Bldg. B, Helgonavägen 3 Telephone +46 46 222 83 15 Email kristina.arnrup_thorsbro@kansliht.lu.se Website www.ht.lu.se Facul ty Board ’s work ing commit tee General syllabus for third-cycle studies for the Degree of Doctor in Classical Archaeology and Ancient History This syllabus was approved by the Board of the Joint Faculties of Humanitie