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Extracellular matrix (ECM) remodeling has been associated with chronic lung diseases. However, information about specific age-associated differences in lung ECM is currently limited. In this study, we aimed to identify and localize age-associated ECM differences in human lungs using comprehensive transcriptomic, proteomic, and immunohistochemical analyses. Our previously identified age-associated

Wind, rain, herbivores, obstacles, neighbouring plants, etc. provide important mechanical cues to steer plant growth and survival. Mechanostimulation to stimulate yield and stress resistance of crops is of significant research interest, yet a molecular understanding of transcriptional responses to touch is largely absent in cereals. To address this, we performed whole-genome transcriptomics follow

Bayesian inference can be extended to probability distributions defined in terms of their inverse distribution function, i.e. their quantile function. This applies to both prior and likelihood. Quantile-based likelihood is useful in models with sampling distributions which lack an explicit probability density function. Quantile-based prior allows for flexible distributions to express expert knowle

Colloidal halide perovskite nanocrystals are promising candidates for next-generation optoelectronics because of their facile synthesis and their outstanding and size-tunable properties. However, these materials suffer fromrapid degradation, similarly to their bulk perovskite counterparts. Here, we survey the most recent strategies to boost perovskite nanocrystals stability, with a special focus o

In this chapter, we explore how audit professionals in transnational accounting firms feel about their professional identity in the digital age. Based on 15 interviews with audit professionals, our findings reveal that despite the dispositional and relational affordances of emerging digital technology, some auditors are experiencing professional insecurities. Our interviewees expressed concerns on

Presented at workshop II, "Fracture Mechanics and Design of Concrete Structures" at FRAMCOS-2 in Zürich, 1995

This chapter is a commentary on the book as a whole. Based on the overall PeTS project, the empirical findings from the four educational settings and the conceptual portions of the book, this chapter focuses on three specific aspects of peer group mentoring: the move from teaching as a private matter to teaching as a collegial responsibility, the relationship between collegiality and peer group me

Theorizing simplifies reality by means of "isolation" whereby some phenomena or aspects thereof are excluded from consideration. Using the case of the resource-based view, we discuss how theorists isolate. We develop a case for symmetrical isolations, show that the RBV violates a symmetry requirement, argue that a more symmetrical RBV implies novel insights in value creation and appropriation, and

The main objective of this work is the application of variational concepts to microscopic multiple particle systems (MPS) which are assigned to corresponding points of a macroscopic continuum. Due to this underlying micro-structure it is not sufficient to simulate the macroscopic behavior with pre-assumed (overall) material parameters, or rather constitutive-law-based standard methods. Therefore,

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