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Is there a universal hierarchy of the senses, such that some senses (e.g., vision) are more accessible to consciousness and linguistic description than others (e.g., smell)? The long-standing presumption in Western thought has been that vision and audition are more objective than the other senses, serving as the basis of knowledge and understanding, whereas touch, taste, and smell are crude and of
Hypothalamus (HT) is a brain structure which serves as a coordination center for several vital body functions. Craniopharyngioma (CP) is a pituitary tumor with high morbidity, primarily due to HT lesion. Among important consequences of CP are cognitive dysfunction and intractable weight gain due to HT obesity, resulting in high cardiovascular (CV) risk. A better understanding of the structural bra
Popular Abstract in Swedish Många cancerceller har ovanligt höga nivåer av proteinet DEK och i vissa fall av leukemi har man hittat en genetisk förändring som leder till en variant kallad DEK-NUP214. Man tror därför att DEK kan vara en av faktorerna som bidrar till att vanliga celler omvandlas till cancerceller. En sådan roll har visats i experimentella modeller där man även sett att cancerceller The DEK gene is upregulated in a growing number of cancers and translocated to form the DEK-NUP214 fusion gene in a subset of acute myeloid leukemia. In this thesis, we studied the cellular and molecular functions of the DEK and DEK-NUP214 proteins. We found that the expression of DEK is increased by the leukemia-associated fusion protein NUP98-HOXA9, suggesting that DEK may be a downstream mediat
The kallikrein gene family (KLK1-KLK15) is the largest contiguous group of protease genes within the human genome and is associated with both risk and outcome of cancer and other diseases. We searched for copy number variants in all KLK genes using quantitative PCR analysis and analysis of inheritance patterns of single nucleotide polymorphisms. Two deletions were identified: one 2235-bp deletion
Purpose Biofilm infections have a major role in implants or devices placed in the human body. As part of the endourological development, a great variety of foreign bodies have been designed, and with the increasing number of biomaterial devices used in urology, biofilm formation and device infection is an issue of growing importance. Methods A literature search was performed in the Medline databas
Immunocytochemistry for transactive response binding protein-43 (TDP43) was assessed in the granular cell layer of the dentate gyrus in 250 cases displaying hippocampal pathology identified by haematoxylin-eosin staining. 18%, nearly one in five displayed TDP43 immunoreactive pathology in the granular cell layer of hippocampus. This percentage increased to 43% when only subjects with hippocampal p
Dowry payments from the family of the bride to that of the groom were rarely encountered in Kerala during the early twentieth century, but now are almost universal. Based on an examination of historical documents, including legislative debates, court cases, and reports, the way dowry was explained in the past is compared with the results of 200 contemporary interviews to determine its current rati
Since knowability must emanate from the single individual, singularity constitutes the frame of reference, and the embodiment of knowing is expected to emerge through individual text production. Furthermore, the basis of the presented studies will consist of text materials with unknown frame factors. This is especially underlined by the fact that history at the Times of Tacitus was an art, not a s
Excited states in the N = Z - 2 nucleus (44)V have been observed for the first time. The states have been identified through particle-gamma-gamma coincidence relationships and comparison with analog states in themirror nucleus (44)Sc. Mirror energy differences have been extracted and compared to state-of-the-art shell-model calculations which include charge-symmetry-breaking forces. Observed decay
In the search for the fully aligned 27(-) state in Nd-140 predicted by cranked Nilsson-Strutinsky calculations, new close-to-spherical high-spin states have been discovered. Both the close-to-spherical and the triaxial calculated states are in good agreement with the experimental results, supporting the existence of shape coexistence up to very high spins. Shell-model calculations using a newly de
Studies on dissolved silicate (DSi) and biogenic silica (BSi) dynamics were carried out in the Oder estuary, Baltic Sea in 2000-2005. The Oder estuary proved to be an important component of the Oder River-Baltic Sea continuum where very intensive seasonal DSi uptake during spring and autumn, but also BSi regeneration during summer take place. Owing to the regeneration process annual DSi patterns i
Prior to the end of the Cold War, China's foreign policy was in large shaped by a confrontational, power-based discourse. However, since the early 1990s, China's foreign policy in general and its regional policy in particular has undergone significant change. Today, China operates in large with, and within major international and regional institutions and regimes. This is also notable conc
The aim of this thesis is to discuss the construction of Taiwanese identity in Shanghai and compare with the studies on identity formation in Taiwan itself. The thesis is divided into three parts: cultural identity, ethnic identity and political identity. A total of 10 male and female students from Taiwan who had resided a year and above and enrolled in higher education in Shanghai were interviewe
This thesis deals with driving forces for CSR reporting in China. More and more international companies have published their CSR reports under the concern of sustainable development. Chinese companies are facing the environmental and social challenges in China today. CSR reporting has been taken as a sustainable development strategy by the Chinese Central Government and the pioneering Chinese comp
Building the European identity and strengthening the concept of European citizenship is a task that can be achieved through various ways. One of the most powerful tools is represented by the system of education. Since the inception of the Community action programmes in this field, pupils, students and teachers take part actively in a new form of socialisation at the European level. Realised in th
