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The purpose of the present experiments was to study the effects of a combined cholinergic and serotonergic denervation of the rat forebrain on spatial learning using the Morris water maze task. Experiment 1 compared the acute effects of a radiofrequency lesion of the septum, an intraventricular 5,7-dihydroxytryptamine (5,7-DHT) lesion, and a combined septal plus 5,7-DHT lesion. Although the 5,7-DH
Almost three out of four EU citizens live in urban areas. Knowledge on the city’s environmental structure and capabilities is needed as urbanization is expected to continue. In this study, eight indicators on urban ecosystems condition (ECIs) were quantified for 305 EU cities (>100.000 inhabitants). A composite indicator (CI), based on the ECIs, indicated differences between northern and southern
Earth system models (ESMs) are key tools for providing climate projections under different scenarios of human-induced forcing. ESMs include a large number of additional processes and feedbacks such as biogeochemical cycles that traditional physical climate models do not consider. Yet, some processes such as cloud dynamics and ecosystem functional response still have fairly high uncertainties. In t
Monitoring soil moisture at the Earth'surface is of great importance for drought early warnings. Spaceborne remote sensing is a keystone in monitoring at continental scale, as satellites can make observations of locations which are scarcely monitored by ground-based techniques. In recent years, several soil moisture products for continental scale monitoring became available from the main space age
Purpose: To understand if physical therapy in addition to individualized psychiatric specialist treatment could aid sedentary patients with schizophrenia spectrum disorders or affective spectrum disorders to become more physically active and also to identify assessments suitable for measuring physical activity, physical function and movement motivation. Materials and methods: In a longitudinal, cl
The standard way today to obtain measures of inflationary expectations is to use questionnaires to ask a representative group of respondents about their beliefs of the future rate of inflation during the coming 12 months. This type of data on inflationary expectations as well as on inflationary perceptions has been collected in a unified way on an EU-wide basis for several years. By now, probably
The gray seal (Halichoerus grypus) population in the Baltic Sea is flourishing. On the one hand, this can be interpreted as successful conservation management but, on the other, the gray seal has also become a persistent problem for small-scale coastal fisheries. Departing from the appraisal theory of emotion, this case study investigated local people’s appraisals of the current situation of small
Pressurised meltwater has a major impact on ice dynamics, as well as on sedimentary and deformational processes occurring below/in front of glaciers and ice sheets, but its role in glaciotectonic processes is yet to be fully understood. This study explores micro- and macroscale structures developed within décollements in two thrust-block moraines of Late Weichselian age in Melasveit, western Icela
Mexico is the most transited corridor in the world. Beyond borderlands, human rights abuses committed against migrants pervade across transit communities and routes. In the interior of Mexico, not only at borders, the criminalization of migration has occurred having as a backdrop violence, xenophobia and insecurity in transit communities. Transit communities have developed complex relationships wi
Introduction: In palliative care, family caregivers are often faced with experiences of grief in anticipation of the loss of a close person. An instrument designed to measure this form of grief is the Anticipatory Grief Scale, which includes 27 items and has been used in several studies in various contexts. However, the instrument has not been validated. Aim: The aim was to evaluate the psychometr
BACKGROUND: Most evidence for TSC-associated neuropsychiatric disorders (TAND) to date have come from small studies and case reports, and very little is known about TAND in adults. We explored baseline TAND data from the large-scale international TOSCA natural history study to compare childhood and adult patterns, describe age-based patterns, and explore genotype-TAND correlations.RESULTS: The stu
Introduction Obstetric anal sphincter injury (OASIS) occurs in 5%-7% of normal deliveries and increases with vacuum extraction (VE) to 12%-14% in nulliparous women in Sweden. Lateral/mediolateral episiotomy may reduce the prevalence of OASIS at VE in nulliparous women. The current use of episiotomy is restrictive. The protective effect and consequences are uncertain. This trial will investigate if
Climate‐warming induced permafrost thaw exposes large amounts of carbon and nitrogen in soil at greater depths below the seasonally‐thawing active layer. The extent to which plant roots can reach and interact with these hitherto detached, deep carbon and nitrogen stores remains unknown. We aimed to quantify how permafrost thaw affects root dynamics across soil depths and plant functional types com
Background: Macrophage migration inhibitory factor is a proinflammatory cytokine that has been associated with various psychiatric disorders. MicroRNA-451a can directly target macrophage migration inhibitory factor and downregulate its expression in cells. However, the role of macrophage migration inhibitory factor and microRNA-451a in psychiatric patients treated with psychotherapeutic interventi
Five mutations in the ligand-binding domain of the androgen receptor gene were identified in patients with complete (A765T, C784Y, R831X and M895T) or partial (R830G) androgen insensitivity, A765T and R831X have been reported previously whereas the other three mutations are novel. Receptors carrying these mutations were transiently expressed in COS-1 cells, and androgen binding and capacity to tra
Diverse and complex interactions as well as multi-actor systems characterise resource use and re- source policy. This makes system analysis a relevant tool to orient resource policy towards the long term. Analysing such complex systems requires systemic thinking, consideration of causal loops as well as time-lags and delays in system responses.In the SimRess project, system analysis encompassed pa
Many mammals have specialized nose-tips with glabrous and often wet skin, called rhinaria. The function of the rhinarium is unknown in most species. Rhinaria differ not only in shape and skin structure, but also in skin temperature. They are considerably colder in carnivorans than in herbivorous artio- and perissodactyls. Domestic dogs are carnivorans and their noses often feel cold, such that the
In this study, the presence of anisakid nematodes in the European eels (Anguilla anguilla L.) was investigated. A total of 30 specimens of eels were caught by local fishermen from the Buyuk Menderes River, Turkey. Nematoda species of Raphidascaris acus was found from eels. This is the first record of R. acus from A. anguilla from Turkish waters. The ribosomal DNA (rDNA) internal transcribed spacer
