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Popular Abstract in Swedish Normalt sett skyddar immunförsvaret oss mot farliga och främmande ämnen. En cancercell uppfattas oftast som något defekt och farligt som måste elimineras. Men då och då lyckas cancerceller överleva och manipulerar då vårt immunförsvar till det sämre för oss. Cancer är ett samlingsnamn på sjukdomar orsakade av en ansamling av genetiska förändringar. Dessa förändringar Immune cells play paradoxical roles in cancer progression. On one hand, the immune system protects us against tumor development by recognizing and eliminating cancerous cells. On the other hand, tumor-associated immune cells can contribute to tumor progression by secreting growth factors as well as immunosuppressive, pro-angiogenic and/or pro-metastatic mediators. In this thesis we identified a f

Calcium phosphates have been of great interest in the field of medicine for many decades due to their biocompatibility, hardening properties and diverse areas of application. In this study two different alpha phase tricalcium phosphate powders were produced of distinctly different particle size distributions. These two powders were then tested for reactivity and phase evolution. X-ray diffraction

Popular Abstract in Swedish Denna studie fokuserar på distriktssköterskors hälsovägledning i barnhälsovården. Syftet med studien är att öka förståelsen för hur hälsovägledning utformas och genomförs, samt att generera teori, användbar för praktisk barnhälso-vårdsverksamhet. Data samlades in genom videoobservationer med efterföljande intervjuer, fältanteckningar, anteckningar från gruppdiskussionerChild Health Services (CHS) form a strategic arena for Swedish health promotion, from a societal as well as individual perspective. The present study focuses on district nurses´ health counselling in CHS. The aim is to improve understanding of what is important in shaping and accomplishing health promotion, and to generate theory useful in a CHS context. Data were collected at CHS in primary healt

Sequential isolates from eight cynomolgus monkeys experimentally infected with Simian immunodeficiency virus (SIVsm, of sooty mangabey origin) were tested for coreceptor use in the human osteosarcoma indicator cell line, GHOST(3), expressing CD4 and one or another of the chemokine receptors CCR3, CCR5, CXCR4, BOB, or the orphan receptor Bonzo. The indicator cell line carries the human immunodefici

Hakkarainen and Sintonen (2002) praise the descriptive adequacy of Hintikka's Interrogative Model of Inquiry (imi) to describe children's practices in an inquiry-based learning context. They further propose to use the imi as a starting point for developing new pedagogical methods and designing new didactic tools. We assess this proposal in the light of the formal results that in the imi characteri

The paper describes a novel method for self tuning cylinder pressure based heat release computation that is suitable for online usage in e.g. combustion phasing control applications. The method estimates the polytropic exponents and cylinder pressure offsets immediately preceding and succeeding the combustion event respectively using a fast nonlinear least squares method. The polytropic exponent a

In Statistical Shape Modeling, a dense correspondence between the shapes in the training set must be established. Traditionally this has been done by hand, a process that commonly requires a lot of work and is difficult, especially in 3D. In recent years there has been a lot of work on automatic construction of Shape Models. In recent papers (Davies et al., Medical Image Computing and Computer-Ass

Rheumatoid arthritis (RA) is associated with certain MHC class II alleles and is characterized by a chronic autoimmune response in the joints. Using transgenic mice expressing human DR4 (DRB1*0401) and human CD4, but lacking endogenous MHC class II, we show that posttranslational glycosylation of type II collagen (CII) influences the level of T cell tolerance to this candidate cartilage-specific a

We comment on the work by R. Taylor presented at Euro-Crypt'94 (see this proceedings). We first extend some known results on authentication codes with arbitration to the case when protection against arbiter's attacks is provided. We give lower bounds on the secret key size for each participant and give a construction showing that these bounds are tight. These results improve upon previously known

Gold-bearing pyrite ores are refractory and must be pre-treated to break down the sulphides by oxidation. This is done usually by roasting, bacterial oxidation and smelting. Moreover, ores with high sulphur content require pre-treatment to prevent excessive chlorine consumption, an important source of pollution. The pyrite waste created in mining operation presents serious problems on the environm

Popular AbstractI avhandlingen undersöks den ekonomiska omvandlingsprocess som skett i Sverige sedan mitten av 1970-talet. Av speciellt intresse är hur och varför de fördelar som företag och branscher åtnjuter på grund av samlokalisering med andra ekonomiska aktörer (så kallade agglomerationsexternaliteter) varierar över olika faser av ekonomisk omvandling. Avhandlingen baserar sig på de framsteg This thesis investigates the process of economic transformation taking place in Sweden since the mid 1970s. Especially, it is concerned with how and why benefits that firms and industries draw from regional co-location with other actors (agglomeration externalities) vary over stages of economic transformation. Drawing on recent findings within the fields of evolutionary economics and evolutionary

Haemophilus influenzae is an important respiratory tract pathogen responsible for a variety of infections in humans. Encapsulated H. influenzae belongs to one of six serotypes (a-f), of which type b is the most virulent one causing serious and sometimes life-threatening diseases (e.g., epiglottitis, septicaemia and meningitis). In contrast, non-typeable H. influenzae (NTHi) accounts for the majori

This thesis dwells upon the synthesis of system-theoretical tools to understand and control the behavior of nonlinear networked systems. This work is at the crossroads of three topics: synchronization in coupled high-order oscillators, inverse optimal control and the application of inverter-based power systems. The control and stability of power systems leverages the theoretical results obtained f

The bacterial species Cutibacterium acnes (formerly known as Propionibacterium acnes) is tightly associated with humans. It is the dominant bacterium in sebaceous regions of the human skin, where it preferentially colonizes the pilosebaceous unit. Multiple strains of C. acnes that belong to phylogenetically distinct types can co-exist. In this review we summarize and discuss the current knowledge

Sweden experienced a dramatic shakeout of the older workforce in the first half of the 1990s as part of the economic crisis 1991-94. The labour force participation rates and, even more pronounced the employment rates for the older workforce sank dramatically. However, when the Swedish economy recovered in the latter half of the 1990s the employment rates for the older workers, both for men and wom