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Background: Amyotrophic lateral sclerosis (ALS) is invariably fatal but there are large variations in the rate of progression. The lack of predictability can make it difficult to plan clinical interventions. This includes the requirement for gastrostomy where early or late placement can adversely impact quality of life and survival. Methods: We designed a model to predict the timing of gastrostomy
BACKGROUND: Early-life exposure to per- and polyfluoroalkyl substances (PFAS) may impact the developing lungs and immune system and increase the risk of childhood asthma, but no studies have been conducted in a high-exposed population. The objective of this study was to estimate associations between prenatal PFAS exposure and childhood incidence of asthma and wheeze in Blekinge County, Sweden, whe
Air emissions are becoming a larger problem in today’s society and therefore the limits are getting stricter. This means that chemical-producing industries which create multiple byproducts, acting like air pollutants, requires to improve their emission limiting systems. Johnson Matthey Formox AB is a company who sells licenses and catalysts for formaldehyde production by the FORMOXTM process. Prod
Acquired aplastic anemia (AA) is considered to be an autoimmune mediated disease whereas in inherited bone marrow failure syndromes the genetic abnormalities account for the bone marrow dysfunction. The only curative treatment for inherited AA is hematopoietic stem cell transplantation (HSCT). Successful treatment for acquired AA has traditionally been considered with HSCT, whereas single agent th
AIM: The aim of this study was to evaluate wound healing, major amputation and mortality in patients with diabetic foot ulcer and peripheral arterial disease (PAD), and to compare the group decided to have an endovascular intervention with groups referred to conservative treatment or to those judged as unreconstructable. METHODS: A retrospective two-year review of all patients with diabetic foot
The aim was to study dentists' judgement on the removal of and on the development of pathology associated with asymptomatic mandibular third molars. Thirty general dental practitioners (GDPs) and 10 oral surgeons were asked to judge 36 molars with equal distribution of three cues: patient's age, angular position and degree of impaction of the molar. Rating on a VAS was found to be an appropriate m
Common diseases such as type 2 diabetes are phenotypically heterogeneous. Obesity is a major risk factor for type 2 diabetes, but patients vary appreciably in body mass index. We hypothesized that the genetic predisposition to the disease may be different in lean (BMI<25 Kg/m(2)) compared to obese cases (BMI >= 30 Kg/m(2)). We performed two case-control genome-wide studies using two accepted cut-o
Network re-optimization is a process that must be triggered periodically in order to improve the inefficient resource allocation of online routing heuristics due to the uncertainty of online lightpath demand arrivals and departures. Network re-optimization involves two tasks: a) finding new lightpaths for a (sub)set of current demands, i.e. rerouting, and b) migrating the current traffic to the ne
Att färdas i mörker: insekters lösningar, vinster och kostnaderIn sin ständiga jakt på mat måste många insekter undvika att krocka med grenar, stenar och blad, samt färdas i en lämplig kompassriktning. Åtskilliga insekter använder sin syn för att kontrollera detta. En nektarsökande humla, till exempel, reglerar sin flyghastighet efter hur snabbt föremål i omgivningen rör sig över dess ögon. Denna Flying, as well as walking insects rely on vision to regulate locomotion, even in the dark when the visual system is much less reliable. To manage visual control of these behaviours at low light intensities, many insects have evolved optical adaptations, such as larger facet lenses and wider rhabdoms, and neural adaptations, such as spatial and temporal summation, to increase their visual sensitiv
Popular Abstract in Swedish Jonstråleanalys är ett fält inom tillämpad fysik vars utövare sysselsätter sig med bestrålning av olika föremål med joniserande strålning från partikelacceleratorer. Fysiker och kemister observerade i början av nittonhundratalet att joniserande strålning såsom alfapartiklar från radioaktiva källor ger upphov till olika sorters strålning när den växelverkar med materiThe overall goal of this thesis is to test new detector technologies and data acquisition systems, for use in Ion Beam Analysis IBA. This is intended to complement the existing setup, which is routinely used at Lund Ion beam Analysis Facility LIBAF. Proton induced X-ray emission is a well-known method for trace element analysis of heavier elements, but trace element analysis of elements below alum
This study explores musicians' ways of taking and giving meaning to notation in Western tonal music. From a socio-cultural theoretical perspective relations between traditions and individuals were especially accounted for. Linked to this perspective the method for the study was developed. Experienced pianists commented on well-prepared performances of one freely chosen work, and prescribed pieces
The landscape matrix is suggested to influence the effect of habitat fragmentation on species richness, but the generality of this prediction has not been tested. Here, we used data from 10 independent studies on butterfly species richness, where the matrix surrounding grassland patches was dominated by either forest or arable land to test if matrix land use influenced the response of species rich
Weathering of silicate minerals releases dissolved silicate (DSi) to the soil-vegetation system. Accumulation and recycling of this DSi by terrestrial ecosystems creates a pool of reactive Si on the continents that buffers DSi export to the ocean. Human perturbations to the functioning of the buffer have been a recent research focus, yet a common assumption is that the continental Si cycle is at s
The 10th Nordic TAG conference fell together with the 150th anniversary of the publication of Charles Darwin’s seminal On the Origin of Species as well as the 200th anniversary of his birth. Over the last 15 years a new theoretical discourse on the use of evolutionary theory in archaeology has emerged, but this has largely bypassed the Scandinavian countries, despite the fact that Scandinavian arc
This report is written during a Master Thesis carried out at Volvo Aero Corporation, VAC, in relation with the Division of Production and Materials Engineering at Lund Institute of Technology. The purpose with this report is to get a better insight in some of the problems occurring during the manufacturing of a space nozzle. At VAC a new kind of nozzle wall design has been introduced for their sp
When a child is diagnosed with diabetes, the symptoms may be in its most severe form with ketoacidosis, to mild symptoms of diabetes, detected incidentally. Moderate and severe symptoms of diabetes presentation require infusion therapy and thereby necessitate hospitalisation for the first few days. The initial management is largely a preparation for family members to help them gain the practical u
This paper presents a joint experimental and large eddy simulation (LES) study of lean premixed low swirl stabilized methane/air flames at different Reynolds numbers (Re similar to 20,000-100,000). The aims are to investigate the sensitivity of the structures and dynamics of low swirl flames to the inflow boundary conditions and to evaluate the capability of an LES flamelet model in predicting the
Clay boards are emerging as a sustainable alternative to gypsum boards for fire protective linings in timber structures. However, their fire behaviour is still not well understood. Most existing studies focus on full scale systems, which show when a board fails but not why it fails. This thesis addresses this gap by investigating two commercial clay board variants with different compositions, dens
