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Polyclonal protein HC-IgA complexes (HC-IgA) were isolated from two different serum pools. Their hydrodynamic volumes were found to be slightly greater than that of monomeric IgA but less than that of dimeric IgA. Sodium dodecyl sulphate (SDS)-polyacrylamide gel electrophoresis of reduced and carboxymethylated complexes followed by immunoblotting showed that the complexes contained normal light an

In chapter 33, Hallonsten argues that the change in the historical context of Big Science, from the Cold War to contemporary innovation driven economies, has transformed its character and raised anew the issue of its legitimization. According to Hallonsten, the promotion of Big Science projects, as a result of their uncertain epistemic and technological payoff, often entails 'overselling' marketin

Diabetic muscle atrophy is an inflammation-related complication of type-2 diabetes mellitus (T2DM). Even though regular exercise prevents further deterioration of atrophic status, there is no effective mediator available for treatment and the underlying cellular mechanisms are less explored. In this study, we investigated the therapeutic potential of MCC950, a specific, small-molecule inhibitor of

We witness rising tensions between online gig-economy platforms, incumbent firms, regulators, and labor unions. In this chapter, we use the framework of institutional logics as an analytical lens and scheme to understand the fundamental institutional challenges prompted by the advent of the online gig economy. We view gig-economy platforms as corporations that organize and self-regulate markets. I

As the introductory chapter sets out, this volume critically interrogates the EU as a global actor and its normative power in global politics as part of the 2013 European Research Day of the Centre for European Research at Gothenburg University. This chapter will conclude this interrogation by providing a Copenhagen reflection on the EU as a global actor within the context of the Normative Power A

The bi-component leukocidins of Staphylococcus aureus are important virulence factors that lyse human phagocytic cells and contribute to immune evasion. The γ-hemolysins (HlgAB and HlgCB) and Panton-Valentine leukocidin (PVL or LukSF) were shown to assemble from soluble subunits into membrane-bound oligomers on the surface of target cells, creating barrel-like pore structures that lead to cell lys

The aim of these experiments was to obtain a detailed knowledge of how the orbicularis oculi muscle is activated during the execution of a conditioned eyeblink response (CR). This is the first critical step to understand the underlying neural mechanisms involved in the control of the CR. Decerebrate ferrets were trained in a classical conditioning paradigm. The conditioned stimulus (CS) was a trai

As smart and as stupid, as well- and ill-informed, as curious and closed-minded as any random sample, tourists represent a unique object of study, as they are “the last remaining class that exhibits consciousness for itself” (MacCannell, 2013 p.xix). Technology has been transforming the tourist experience deeply, as it both fulfils a functional purpose of performing tasks for humans, and it holds

The pressure on European air-traffic logistics increases, both at the airports and in the sky, as the passenger rate increases. Handling airborne aircraft is becoming more rationalized as an effect of sophisticated technology and lower separation-minima. Technological and legal development at airports is lagging behind causing delays. Airport operations might be more efficient by increasing accura

Information and Communication Technologies for education (ICT4E) have been playing an increasingly important role in schooling and training worldwide. On the one hand, they are expected to bridge various divides e.g. between developed and developing countries, urban and rural regions, affluent and poor neighborhoods etc., by spreading the most up-to-date knowledge and skills into every classroom o