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Here a synthesis of novel galactose-1,2,3-triazole conjugates is described. The title compounds were obtained from 3-azido-3-deoxy-1,2: 5,6-di-O-isopropylidene-α-D-galactofuranose via a copper catalyzed azide-alkyne 1,3-dipolar cycloaddition reaction. It was demonstrated that the title compounds in their isopropylidene-protected form tend to chelate copper. The copper content can be diminished to
Background Achievement of global health goals will require assessment of progress not only nationally but also for population subgroups. We aimed to assess how the magnitude of socioeconomic inequalities in health changes in relation to different rates of national progress in coverage of interventions for the health of mothers and children. Methods We assessed coverage in low-income and middle-inc
Antibody-based microarrays is a novel technology with great promise for high-throughput proteomics. The process of designing high-performing arrays has, however, turned out to be challenging. Here, we have designed the next generation of a human recombinant scFv antibody microarray platform for protein expression profiling of nonfractionated biotinylated human plasma and serum proteomes. The setup
Multimeric lactosides based on carbohydrate scaffolds with valencies ranging from 1 to 4 and different linker lengths were synthesized by a copper-catalyzed azide-alkyne cycloaddition (CuAAC). The binding affinities and crosslinking abilities of the new "click clusters" toward biologically relevant galectins (gal-1, gal-3) and peanut lectin were evaluated by fluorescent polarization assay (FPA) an
The birth and development of Gothicist ideas and their use in Spanish-Swedish contacts
Popular Abstract in Swedish Sexuella övergrepp väcker starka känslor hos oss. Ibland tycks känslorna bli så svåra att vi försöker utestänga den plågsamma verkligheten genom att "blunda" för faktum. För att studera hur människor handskas med förekomsten av ett sexuellt övergrepp på ett barn i en bild, framställdes en bild, som avsåg att visa ett sådant övergrepp. Bilden visades för ett stort antal This investigation comprises five studies of factors determining adults' interpretations of a picture (Threat), drawn to represent sexual abuse of a child. The sexes of the two persons in the picture were on purpose drawn ambiguously. In Study I, the Threat picture was interpreted by 515 undergraduates in three experiments, all resulting in the same four interpretation categories, and similar freq
Popular Abstract in Swedish Immunförsvaret är till för att bekämpa patogener såsom bakterier, virus, parasiter och svamp. Det kan också bekämpa cancerceller även om dessa har en förmåga att undkomma till slut. För att kunna känna igen och eliminera främmande kroppar måste immunförsvaret kunna skilja på dem och våra kroppsegna ämnen. Immunförsvaret består av vita blodkroppar. Vita blodkroppar är enT cells constitute a heterogenous population of lymphocytes. Their unifying property is that they express surface bound antigen-receptors, called T cell receptors (TCRs). The TCR is a heterodimer composed of either TCRalpha and beta chain proteins (alphabeta TCR) or gamma and delta chain proteins (gammadelta TCR). Depending on which TCR isotype that is expressed, the T cells are divided into alpha
A previous study compared two student groups that played a mathematics game based on a teachable agent. One group played with, and the other without, the inclusion of a social conversation module: a chat between the student and the teachable agent. Results were that students who used the game with the chat included had a more positive experience of the game and learned more in the sense of teachin
It is easy when studying the literature on the current development toward closer more integrated business to business relationships to get the impression that a close integrated relationship is desired for all circumstances. Instead, this thesis shows that the nature of business relationship is very strongly correlated to product supplied. The focus of this thesis has been a case study between a s
The state of the farming industry in Europe has been put under the spotlight in recent years due to a number of different food scares and disease outbreaks. Many new quality assurance schemes have been formed to accompany the existing environmental monitoring schemes, to give concerned consumers some guarantee when buying food that it is of a good quality and the environmental load of production h
Ongoing work in developing a general structure and a comprehensive components library aiming at modelling liquid-food process lines is presented. The dynamic component models were developed in an object-oriented library structure based on the dynamic modelling language Modelica using the object-oriented graphical tool Dymola. The models were based on fundamental conservation laws and can simulate
The molecular mechanism responsible for the antitumor activity of histone deacetylase inhibitors (HDACi) remains elusive. As HDACi have been described to alter miRNA expression, the aim of this study was to characterize HDACi-induced miRNAs and to determine their functional importance in the induction of cell death alone or in combination with other cancer drugs. Two HDACi, trichostatin A and vori
We present a mathematical model for a distributed process of routing optimization that could be run in the control plane of the Internet using existing EGP routing protocols. A more detailed description of the results presented in this paper is given in [1].
Popular Abstract in Swedish Jorden i vår natur är en mycket komplex miljö som innehåller en mängd olika organismer. Bland dessa är bakterier och svampar av störst betydelse eftersom de står för en stor del av nedbrytningen av olika ämnen. Jordbakterierna utför t.ex. många av ämnesomvandlingarna av kväve, svavel och fosfor i marken. Nedbrytningen frigör näringsämnen som sedan kan utnyttjas av växteThe soil bacterial community is under the constant influence of its environment. Changing any of the factors affecting the bacterial community will induce a selection pressure which, with time, will change the community. In this work the effect of changing the temperature or pH on the soil bacterial community was studied. Measurements using the [3H]-thymidine incorporation technique showed that th
This report summarizes 28 case studies addressing the common interest for indicators in case studies in Nordic and Baltic countries and is distributed to different building types – Benchmarking systems and indicators (4 case studies) – Offices (7 case studies) – Housing (8 case studies) – School and nursery (5 case studies) – Shopping centres (3 case studies) – Hospital (1 case studies) There are
Neutrophils migrate to infected mucosal sites that they protect against invading pathogens. Their interaction with the epithelial barrier is controlled by CXC chemokines and by their receptors. This study examined the change in susceptibility to urinary tract infection (UTI) after deletion of the murine interleukin 8 receptor homologue (mIL-8Rh). Experimental UTIs in control mice stimulated an epi
Miljöcertifieringar för byggnader, anläggningar och stadsdelar tillämpas i dag i allt större utsträckning för att säkerställa hållbar utveckling i den byggda miljön. Deras främsta syfte är att främja sociala och ekonomiska fördelar samt uppnå minimal negativ påverkan på människa och miljö. Kraven för olika certifieringsnivåer är detaljerade och uppbyggda på tydliga betygssystem. Samtidigt har begrThis study aims to, through a comparative analysis, examine if there are any similarities between environmental certification schemes and the nature-inspired design tool Cradle to Cradle in environmental performance when building residential houses. The analysis shows that two of the four examined certification systems, LEED and BREEAM, have several traits that are similar to C2C. However, these s
In 2001, as a reaction to the intra-state conflicts occurring in the 1990s, a commission called the International Commission on Intervention and State Sovereignty (ICISS) published the Responsibility to protect report (R2P). The purpose of the report was to offer a method to prevent the reoccurring crimes against humanity that defined so many conflicts in the 20th century. In order to prevent the
Skatterätten är ett stort rättsområde, sett inte bara till dess rättsliga reglering, utan även till antalet rättshandlingar som har skatterättsliga konsekvenser. En av dessa bedömningar gäller vilket skattesubjekt, d.v.s. vilken fysiska eller juridiska person, som ska ta upp en viss intäkt till beskattning. En annan är till vilket inkomstslag en intäkt ska bestämmas. Huvudsyftet i uppsatsen är atThe field of taxation is a wide field within Swedish law, not only due to the big amount of legal regulations, but also to the number of legal transactions carrying taxation consequences. One specific topic that is under constant judgment is to which person, i.e. which physical or legal person, a specific income should be allocated. Another one is in which income class a specific income should be
