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This work describes a novel fully integrated inductive tongue computer interface for disabled people. The interface consists of an oral unit placed in the mouth, including inductive sensors, related electronics, a system for wireless transmission and a rechargeable battery. The system is activated using an activation unit placed on the tongue, and incorporates 18 inductive sensors, arranged in bot
BACKGROUND: In the European Union alone, more than 100 million people present to the emergency department (ED) each year, and this has increased steadily year-on-year by 2-3%. Better patient management decisions have the potential to reduce ED crowding, the number of diagnostic tests, the use of inpatient beds, and healthcare costs.METHODS: We have established the Skåne Emergency Medicine (SEM) co
This paper presents the development of a character activation time prediction model for tongue-typing. This model is based on a modification of Fitts's law that is more suitable for tip-of-tongue selectivity tasks around the palatal area. The model was trained and evaluated with data from tongue-selectivity experiments using an inductive tongue-computer interface. It takes into account the movemen
Effective human input devices for computer control are very important to quadriplegics and others with severe disabilities. This paper describes a framework for computer control without need for special PC software or drivers. The framework is based on a tongue control system recently developed at Center for Sensory-Motor Interaction (SMI), Aalborg University. The framework provides emulation of a
Ion channels and ion fluxes control many aspects of tissue homeostasis. During oncogenic transformation, critical ion channel functions may be perturbed but conserved tumor specific ion fluxes remain to be defined. Here we used the tumoricidal protein-lipid complex HAMLET as a probe to identify ion fluxes involved in tumor cell death. We show that HAMLET activates a non-selective cation current, w
Popular Abstract in Swedish Infektioner i urinvägar, tarm och luftvägar orsakas av bakterier som speciellt anpassats till respektive vävnad. Infektionen börjar med att bakterien binder till slemhinneytan, och därmed sätter igång inflammation och försvar. Urinvägsinfektioner (UVI) är en värdefull modell för att förstå de molekylära detaljerna som avgör balansen mellan värd och bakterie. UVI orsakaBacterial adhesion to the bladder mucosa is a critical step for the establishment of Escherichia coli bacteriuria. The P-fimbriae, encoded by the pap gene cluster, are considered as virulence factors but the mechanisms have been debated. This study defined the roles for P fimbriation during the early colonization of the human urinary tract. Patients with recurrent UTI were first subjected to deli
Do certain humans and animals have greater value than other humans and animals? The question will be discussed using some examples from pre-Christian burial practices and other depositions of human and animal bones in Scandinavia. During the pre-Christian period it seems that certain humans and certain animals were buried in graves made for the purpose, while other humans and animals were deposite
A calibration model was developed for a non-invasive blood glucose sensor, to determine how the blood glucose data measured by this sensor is related to blood glucose data measured with laboratory capillary finger sticks and to corrupting noise. The variability of calibration models for different patients was analyzed as well as the dynamics of the non-invasive blood glucose sensor according to re
A human milk fraction containing multimeric alpha-lactalbumin (MAL) is able to kill cells via apoptosis. MAL is a protein complex of a folding variant of alpha-lactalbumin and lipids. Previous results have shown that upon treatment of transformed cells, MAL localizes to the mitochondria and cytochrome c is released into the cytosol. This is followed by activation of the caspase cascade. In this st
An organization aiming to survive on a more challenging or changing market has to adapt or fundamentally change the way it is doing business. For the Swedish forest products industry, and more specifically the paper packaging industry, the market challenges range from saturated home markets, competing materials and increasing production costs, to growth of new markets and more powerful actors in t
Popular Abstract in Swedish En av de stora vetenskapliga bedrifterna hittills under 2000-talet är onekligen att man efter många års arbete för första gången lyckades kartlägga (sekvensera) samtliga mänskliga gener. Det mänskliga DNA:t är lokaliserat till cellkärnan och i princip så kan man likna en cellkärna med ett kontrollrum fyllt av manualer (DNA) som talar om cellens sammansättning och hur deProteomics is expected to generate new insights into biological processes as well as identify novel biomarkers and therapeutic targets since most biological functions are transmitted through proteins. However, due to the complexity displayed by a proteome and inherent limitations associated with current methodologies, proteomic analyses often result in incomplete coverage and inconsistent measurem
Firms proactive in environmental work and those pressured by their product chain have a list of restricted substances that they do not want their products to contain. But as environmental management issues progress, what are companies doing to reduce the use of these restricted substances? Brominated flame retardants used in cars, trucks and buses to improve fire safety are a rising public concern
Meristem Wall is a prototype for a 3D-printed building envelope, featuring a dynamically controllable network of integrated air channels that allow a fluid and adaptive relationship between inside and outside. The wall integrates functional lighting and electricity, windows, and a custom CNC-knitted textile interior. It is fabricated through binder-jet sand 3D printing and points towards a climati
Maternal vaccination, resulting in transfer of protective IgG across the placenta, represents a promising strategy to prevent neonatal disease caused by group B Streptococcus (GBS). The prototype vaccine GBS-NN, a fusion protein consisting of the N-terminal domains of the alpha-like protein (Alp) family members AlphaC and Rib, has been shown to display a good safety profile and to elicit a strong
Pregnancy-induced immune modulation might lead to reactivation of latent tuberculosis infection (LTBI). This thesis explores aspects of immune-based LTBI diagnostics and how pregnancy affects the immune control of Mycobacterium tuberculosis (Mtb) infection. We studied a prospective cohort of women recruited during pregnancy in Ethiopia. LTBI testing was performed by quantification of interferon-γ
Background. Mannose-binding lectin (MBL) is a multifunctional protein involved in innate immunity. We tested whether MBL and elevated viral and bacterial antibodies were risk factors for acute coronary events. Design. Controlled cohort study. Methods. A total of 354 patients with unstable angina pectoris (UA) or acute myocardial infarction (AMI) were compared with 334 paired controls. Results. Ent
En jämförelse mellan singel-chipet och dual-chipet: ny tillämpning för akustisk infångning av celler och partiklar Mikrofluidik är ett expansivt område som banar väg för utveckling av ny mikroteknologi inom det medicintekniska området. Genom att studera och försöka förstå hur vätskor och mindre partiklar beter sig på mikroskalan kan man finna lösningar till mer effektiva analysmetoder på exempelvAbstract Microfluidics is the field where the behavior of fluids is studied in very small channels, and small means that the size of the channels normally is only a couple of hundred microns. Fluids in the µL/nL/pL range are handled in microfluidics. There´s a difference in the behavior of fluids on the microscale compared to the macroscale. This difference, taken into consideration yields severa
The Facilities Management industry is the largest business services market in Europe and it is growing fast. At the same time, the industry has matured and added substantial responsibilities beyond the basic maintenance and operational functions that formed the basis of the field and is now described as an emerging multi discipline market. Despite its large share of the market, public FM has got l
