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The optimal duration of treatment with vitamin K antagonists (VKA) after venous thromboembolism (VTE) in patients with Philadelphia-negative myeloproliferative neoplasms (MPNs) is uncertain. To tackle this issue, we retrospectively studied 206 patients with MPN-related VTE (deep venous thrombosis of the legs and/or pulmonary embolism). After this index event, we recorded over 695 pt-years 45 recur
Buildings are getting taller due to increased urbanisation and densification of cities. More advanced construction methods and the desire to construct impressive buildings is also supporting the trend. Due to their inherent slenderness resulting in low eigenfrequencies, these buildings are susceptible to wind-induced vibrations which can be highly disturbing for occupants. Already barely perceivab
Horses have been valued for their diversity of coat colour since prehistoric times; this is especially the case since their domestication in the Caspian steppe in ∼3,500 BC. Although we can assume that human preferences were not constant, we have only anecdotal information about how domestic horses were influenced by humans. Our results from genotype analyses show a significant increase in spotted
The study objective was to describe the types, localizations and severity of injuries among first division Bundesliga football players, and to study the effect of playing position on match and training injury incidence and severity, based on information from the public media. Exposure and injuries data from 1 448 players over 6 consecutive seasons were collected from a media-based register. In tot
In the wake of the arrival of cloud computing, future applications are poised to become more resilient and adaptive by embracing elasticity in an osmotic manner. Although cloud computing is a strong attractor for application developers, thereare still unconquered performance frontiers. Latency-sensitive and missioncritical applications make up a significant portion of all software systems, and the
The observation that neural grafts can induce dyskinesias has severely hindered the development of a transplantation therapy for Parkinson's disease (PD). We addressed the hypothesis that inflammatory responses within and around an intrastriatal graft containing dopamine neurons can trigger dyskinetic behaviors. We subjected rats to unilateral nigrostriatal lesions with 6-hydroxydopamine (6-OHDA)
The Kauffman model describes a particularly simple class of random Boolean networks. Despite the simplicity of the model, it exhibits complex behavior and has been suggested as a model for real world network problems. We introduce a novel approach to analyzing attractors in random Boolean networks, and applying it to Kauffman networks we prove that the average number of attractors grows faster tha
This article explores the notion of borderlands as ambivalent and contested landscapes, as literal and figurative in-between spaces—realms of negotiation, translation and remaking. It is argued that, due to the social and cultural processes taking place in borderlands, they can be usefully scrutinized using concepts developed in postcolonial scholarship. In particular, Homi Bhabha’s concept of the
The authors examine the observed heterogeneity in self-assessed health (SAH) among the aged in India using data on health and living conditions of the elderly in India from the 60th Round of National Sample Survey (2004-2005). Results indicate that almost one fourth of the old in India rate their health as poor, and there exists considerable interstate variations in SAH ratings. Based on hypothese
The current and future costs of willow short rotation coppice production in Sweden are analysed, considering all relevant cost factors explicitly. The future production costs are estimated considering effects of coppice area expansion and learning. The current and future costs of land and of risk premiums are subsequently estimated. Subsidies for farmers are not considered. If the area of willow c
During my time as Director of Studies at the Municipal Music School of Lund, Sweden, I have had several discussions with teachers, students, parents, municipality civil servants, and politicians. I have concluded that in general, culture schools and music schools are looked upon as institutions where parents safely can send their children convinced about that they get a qualified education regardi
Popular Abstract in Swedish Vår kropp består till stor del av proteiner. De bygger upp vår kropp, låter oss röra på armar och ben, se, höra, tänka och känna. Proteiner byggs av cellerna utifrån den individuella ritning - DNA - som vi alla bär med oss i cellernas innersta kärnor. Lika livsviktigt som det är att kunna tillverka alla tusentals olika proteiner är det att kunna bryta ned dem i lagom tIt is a necessity of life to make proteins, and it is an equal necessity to degrade those proteins, to eliminate dysfunctional proteins, and leave room for new ones. The processes of protein synthesis and degradation into peptides - proteolysis - have attracted a great interest during the last decades. The eye contains several highly specialized tissues, in which the protein turnover is of vital
Climate and weather extremes are sporadically recurring events that may have major local or regional impacts on the society and the environment. These events are typically related to unusually high or low temperature, prolonged dry or wet conditions, heavy precipitation, or extreme winds. Extreme events are part of the overall climate and weather alongside average conditions and variability, and t
