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Objective: The clinical significance of QT interval adaptation to heart rate changes has been poorly investigated in atrial fibrillation (AF), since QT delineation in the presence of f-waves is challenging. Therefore, the objective of the present study is to investigate new techniques for QT adaptation estimation in permanent AF. Methods: A multilead strategy based on generalized periodic componen
This paper investigates the role of human agency in 40 phases of regional economic development in 12 Nordic regions over 30 years. It contributes with a theoretical framework to study agency over time and a fuzzy-set qualitative comparative analysis based on a unique dataset combining over 200 interviews, with printed and online sources, and quantitative data. The paper identifies which combinatio
We compute the O(αsα2) and O(αs2α) contributions to the production cross section of a Z boson with one b jet at the Large Hadron Collider (LHC) and study their phenomenological relevance for LHC physics. The accurate prediction of hadronic Z+b-jet production is needed to control a background that greatly affects both the measurement of Higgs-boson properties and the searches of new physics at the
Background: The prevailing diagnostic criteria for CKD are age-independent, but have been challenged in light of the eGFR decline associated with normal aging. The stages of CKD communicate magnitude of risk of ESRD, cardiovascular morbidity, and mortality. Aims: This study aims to provide more insight into the morbidity and mortality associated with eGFR levels corresponding to the current CKD st
Galectins compose a protein family defined by a conserved sequence motif conferring affinity for -galactose– containing glycans. Moreover, galectins gain higher affinity and fine-tune specificity by glycan interactions at sites adjacent to their -galactoside– binding site, as revealed by extensive testing against panels of purified glycans. However, in cells, galectins bind glycans on glycoprotein
Increased organic loading to sediments from eutrophication often results in hypoxia, reduced nitrification and increased production of hydrogen sulfide, altering the balance between nitrogen removal and retention. We examined the effect of short-term exposure to various oxygen and sulfide concentrations on sediment nitrification, denitrification and DNRA from a chronically hypoxic basin in Roskild
Introduction: Mechanical thrombectomy within 6 h after stroke onset improves the outcome in patients with large vessel occlusions. The aim of our study was to establish a model based on diffusion weighted and perfusion weighted imaging to provide an accurate prediction for the 6 h time-window in patients with unknown time of stroke onset. Patients and methods: A predictive model was designed based
Systemic lupus erythematosus (SLE, OMIM 152700) is a systemic autoimmune disease with a complex etiology. The mode of inheritance of the genetic risk beyond familial SLE cases is currently unknown. Additionally, the contribution of heterozygous variants in genes known to cause monogenic SLE is not fully understood. Whole-genome sequencing of DNA samples from 71 Swedish patients with SLE and their
The overall aim of this thesis is to gain a clearer picture of the differences in mobility among the young-old living in Sweden’s large metropolitan regions. This thesis comprises four papers. Paper I explores the inclusion of public transport as an element of mobility among the young-old living in the Stockholm region. Paper II presents an analysis of cycling among older people in the city of Mal
Nonfullerene acceptors (NFAs)-based organic solar cells (OSCs) have recently drawn considerable research interests; however, their excitonic dynamics seems quite different than that of fullerene acceptors-based devices and remains to be largely explored. A random terpolymer of PBBF11 to pair with a paradigm NFA of 3,9-bis(2-methylene-(3-(1,
Objectives The aim of this study was to investigate if occupational exposure to inorganic particles or welding fumes during pregnancy is associated with negative birth outcomes. Design A prospective national cohort study. Setting All single births from 1994 to 2012 in Sweden. Information on birth weight, preterm birth, small for gestational age, smoking habits, nationality, age, occupation, absenc
Under the Paris Agreement, nations have committed to preventing dangerous global warming. Scenarios for achieving net-zero emissions in the second half of this century depend on land (forests and bioenergy) to remove carbon from the atmosphere. Modelled levels of land-based mitigation could reduce the availability of productive agricultural land, and encroach on natural land, with potentially sign
Context: In the Requirements Engineering (RE) process of an Open Source Software (OSS) community, an involved firm is a stakeholder among many. Conflicting agendas may create miss-alignment with the firm's internal requirements strategy. In communities with meritocratic governance or with aspects thereof, a firm has the opportunity to affect the RE process in line with their own agenda by gaining
Background: The possibility to monitor patient's serum proteome during treatment can provide deepened understanding of the biology associated with response to specific drugs. Non-invasive serum sampling provides an opportunity for sustainable repetitive sampling of patients, which allows for more frequent evaluation of the biological response and enhanced flexibility in treatment selection in cont
Cities worldwide adopted lockdown policies in response to the outbreak of coronavirus disease 2019 (COVID-19), significantly influencing people's travel behavior. In particular, micro-mobility, an emerging mode of urban transport, is profoundly shaped by this crisis. However, there is limited research devoted to understanding the rapidly evolving trip patterns of micro-mobility in response to COVI
Transition between stream and droplet regimes in a coflow is typically achieved by adjusting the capillary numbers (Ca) of the phases. Remarkably, we experimentally evidence a reversible transition between the two regimes by controlling exposure of the system to acoustic standing waves, with Ca fixed. By satisfying the ratio of acoustic radiation force to the interfacial tension force, , experimen
