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The interpretation of myocardial perfusion scintigraphy (MPS) largely relies on visual assessment by the physician of the localization and extent of a perfusion defect. The aim of this study was to introduce the concept of the perfusion vector as a new objective quantitative method for further assisting the visual interpretation and to test the concept using simulated MPS images as well as patient
Stress fractures at the tibial diaphysis are prone to delayed union. We hypothesized that the interfragmentary strains in the gap tissue are of magnitudes that prohibit bone formation and healing. If so, a rational treatment would be to widen the fracture gap in order to decrease the strains. This could be achieved by replacing part of the fracture crack with a wide drilled hole. This study analyz
Pressure overload activates cardiac fibroblasts leading to excessive production of extracellular matrix which may contribute to compromised heart function. The activated fibroblast acquires smooth muscle-like features such as expression of smooth muscle alpha-actin (SMA) and SM22 and is therefore referred to as myofibroblast. The molecular mechanisms underlying mechanical stress-induced myofibrobl
When developing software platforms for product lines, decisions on which features to implement are affected by factors such as changing markets and evolving technologies. Effective scoping thus requires continuous assessment of how changes in the domain impact scoping decisions. Decisions may have to be changed as circumstances change, resulting in a dynamic evolution of the scope of software asse
Background and Purpose-In a genome-wide association study and subsequent case-control studies, the single-nucleotide polymorphism rs12425791 on chromosome 12p13 was reported to be associated with ischemic stroke, but this could not be validated in a recent well-powered study. We therefore investigated whether an association between ischemic stroke and rs12425791 could be detected in 3 different ca
Previous studies on gender differences in facial imitation and verbally reported emotional contagion have investigated emotional responses to pictures of facial expressions at supraliminal exposure times. The aim of the present study was to investigate how gender differences are related to different exposure times, representing information processing levels from subliminal (spontaneous) to suprali
Climate change can move the spatial location of resources critical for population viability, and a species' resilience to such changes will depend upon its ability to flexibly shift its activities away from no-longer-suitable sites to exploit new opportunities. Intuition suggests that vagile predators should be able to track spatial shifts in prey availability, but our data on water pythons (Liasi
Objectives To describe the gray-scale and vascular characteristics of endometrial cancer in relation to stage, grade and size using two-dimensional (2D)/three-dimensional (3D) transvaginal ultrasound. Methods This was a prospective multicenter study including 144 women with endometrial cancer undergoing transvaginal ultrasound before surgery. The sonographic characteristics assessed were echogenic
In cerebral palsy (CP) there is an increased risk of scoliosis. It is important to identify a progressive scoliosis early-on because the results of surgery depend on the magnitude of the curve. The Swedish follow-up program for cerebral palsy (CPUP) includes clinical examinations of the spine. The reliability and validity of the assessment method have not been studied. In this study we evaluate th
Hepatobiliary excretion can be a major clearance pathway dictating the pharmacokinetics of drugs. Quantitative prediction of human hepatobiliary excretion of drugs is thus essential in early drug development. Extrapolations from current in vitro models are challenging due to differences in expression of enzymes and transporters from native liver tissue. This study aims to utilise 3D spheroids of p
Since 1986, the Vietnamese socialist state has gradually opened towards the global market. Subsequently, socialist modernity may increasingly be outrivaled by the individualistic culture associated with global capitalism which is now gaining ground in Vietnam, especially among the urban middle-class who can easily access it. Proceeding from a post-colonial feminist framework, this thesis aims to i
This work was carried out for the company Verifyter AB in Lund. Their main customers are microchip manufacturers. Verifyter provides a tool called PinDown that does automatic debugging on their customers' test runs. The tool creates a large amount of data with information about these test runs. The company wants to be able to visualize this data for their customers in order for their customers
This thesis focuses on participatory development discourse in Sweden’s support to civil society in developing countries, channelled through Swedish civil society organisations with which Sida has framework agreements. The thesis uses a modified version of Norman Fairclough’s critical discourse analysis, with an operationalisation of participatory development discourse that defines it as either for
In these days, more and more parents are driving their children to and from school. Road safety has deteriorated in the school’s drop off zones due to the big overload of parents driving their children. The overload of cars causes a lack of space, which means that parking and drop off do not happen legally but in places that are inappropriate which increases problem increases the risk of accident
Stoichiometric and very rich flames of methane have been investigated using nonintrusive laser diagnostics. Absolute concentration profiles of HCO were measured by intracavity laser absorption spectroscopy, and temperature profiles were obtained with laser-induced fluorescence of OH. Premixed CH4 + O-2 + N-2 flames were stabilized at a pressure of 30 +/- 0.3 Torr. These new experimental data were
This article examines what image of Russia is being projected in official rhetoric about the Sochi Olympics. It is argued that the imagined community being displayed is a diverse, inclusive and tolerant nation, even an international example of ethnic conviviality. The article puts this narrative in historical perspective, relating it to the mnogonatsionalnost policies of tsarist, Soviet and post-S
We recently showed that lycopene inhibited lipopolysaccharide (LPS)-induced productions of nitric oxide (NO) and interleukin-6 (IL-6) in murine RAW264.7 macrophages by mechanisms related to inhibition of ERK and nuclear factor-kappa B. Since the assembly of Toll-like receptor 4 (TLR4) in lipid rafts is a key element in LPS induced signaling, we investigated whether this process would be influenced
Objective: To explore the feasibility of using low-cost motion interactive games as a home-based intervention for children with cerebral palsy (CP). Methods: Fourteen children with CP, 6-16 years old, practiced with the EyeToy for PlayStation2 (R) in their homes during 4 weeks. Outcome measures were physical activity monitors, Movement Assessment Battery for Children-2 (mABC-2), Bruininks-Oseretsk
Objectives. Venous thromboembolism (VTE) is a potentially serious complication of hospitalization and immobilization. The use of anticoagulant prophylaxis in acutely ill medical inpatients is still under debate. New data including a recent meta-analysis have recently been published. We aim at studying the efficacy and safety of anticoagulant prophylaxis in acutely ill medical inpatients, and demon
Pollution induced community tolerance (PICT) has been suggested as an end-point measurement less affected by confounding environmental factors compared to standard methods of microbial growth, activity and community composition. We evaluated the use of PICT to determine Cu toxicity in vineyard soils polluted with Cu based fungicides (25-1120 mg Cu kg(-1)). These soils also varied in pH (4.3-7.3),
