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The role of developmental bias and plasticity in evolution is a central research interest in evolutionary biology. Studies of these concepts and related processes are usually conducted on extant systems and have seen limited investigation in the fossil record. Here, I identify plasticity-led evolution (PLE) as a form of developmental bias accessible through scrutiny of paleontological material. I
The chemical evolution of fluorine is investigated in a sample of Milky Way red giant stars that span a significant range in metallicity from [Fe/H] ∼-1.3 to 0.0 dex. Fluorine abundances are derived from vibration-rotation lines of HF in high-resolution infrared spectra near 2.335 μm. The red giants are members of the thin and thick disk/halo, with two stars being likely members of the outer disk
Identification of the perivascular compartment as the point of exchange between cerebrospinal fluid (CSF) and interstitial fluid mediating solute clearance in the brain, named the glymphatic system, has emerged as an important clearance pathway for neurotoxic peptides such as amyloid-beta. However, the foundational science of the glymphatic system is based on rodent studies. Here we investigated w
Researchers have measured superfluid helium’s full dispersion spectrum, explaining discrepancies in previous studies and constraining theories of superfluidity.
Vertical III-V nanowire MOSFETs show potential towards the ultimate transistor scaling. A high transconductance and current density are achieved based on the gate-all-around architecture. This work presents a high-frequency design of such devices, achieving more than 600 GHz cut-off frequencies (fT, fmax), at 20 nm gate length. Furthermore, capacitance design and scaling trends, supported by COMSO
Background: Intermittent claudication requires treatment with secondary prevention to reduce disease progression and the risk of cardiovascular events and to improve quality of life. Health literacy and self-efficacy are important preconditions for the health behaviour changes necessary for adhering to secondary prevention. Aim: Evaluate health literacy in patients with intermittent claudication r
In a few recent papers we introduced the chirality-flow formalism, which was shown to make calculations of tree-level Feynman diagrams simple and transparent. Chirality flow, which is based on the spinor-helicity formalism, allows to often immediately analytically write down a tree-level Feynman diagram in terms of spinor inner products. In this paper, we argue that there is also a significant s
This paper presents a diffractive dialogue between ethnographic accounts of imagery, digital or computational imaging, and art and archaeology practices. It develops the notion of images in the making in the context of the digital domain, to discuss what an image is and can be today. It focuses on two digital imaging techniques developed within archaeology and cultural heritage – reflectance trans
Essays in this Issue of Shuddhashar centralize the roles and powers of documents (and the lack of ‘proper’ documents). In parallel, this essay highlights two short stories to show how the power of documents shapes subaltern lives. I dissect the dichotomous dis/possession of documents around which urban poor’s lives are organised. While the state institutions are required to protect and care about
Critical security studies examine how everyday life is affected or transformed by practices that militarise civil society. This article addresses one such area: qualitative changes in the openness and transparency of public administration, instating a mode of suspicion and secrecy. The article is based on interviews and observations in the area of the total defence in Sweden, where we during three
Anthropocene has become an environmental buzzword. It denotes a new geological epoch that is human-dominated. As mounting scientific evidence reveals, humankind has fundamentally altered atmospheric, geological, hydrological, biospheric, and other Earth system processes to an extent that the risk of an irreversible system change emerges. Human societies must therefore change direction and navigate
Background: Dyscarbia is common in out-of-hospital cardiac arrest (OHCA) patients and its association to neurological outcome is undetermined. Methods: This is an exploratory post-hoc substudy of the Target Temperature Management (TTM) trial, including resuscitated OHCA patients, investigating the association between serial measurements of arterial partial carbon dioxide pressure (PaCO2) and neuro
