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Background: Islet autoantibodies form the foundation for type 1 diabetes (T1D) diagnosis and staging, but heterogeneity exists in T1D development and presentation. We hypothesized that autoantibodies can identify heterogeneity before, at, and after T1D diagnosis, and in response to disease-modifying therapies. Methods: We systematically reviewed PubMed and EMBASE databases (6/14/2022) assessing 10
Induced abortion is as common in religious as secular cultures, but interpretations and ways to handle abortion differ. This study focuses on existential aspects of abortion, in relation to a secularized context, through in-depth interviews with 24 Swedish women. Existential questions belonging to four areas were found: Life and Death, Meaning of Life, Morality, and Self-Image. Furthermore, four d
Background: Epidemiological studies show an increasing incidence of traumatic brain injury (TBI) among people aged 65 years and older. Advances in neurointensive care have improved survival after TBI. There is a need for knowledge about long-term outcome after TBI among older survivors of TBI. Objective: To describe the overall outcome, long-term functioning, and disability of the participants in
A search is conducted for new phenomena in events with a top quark pair and large missing transverse momentum, where the top quark pair is reconstructed in final states with one isolated electron or muon and multiple jets. The search is performed using the Large Hadron Collider proton-proton collision data sample at a centre-of-mass energy of s = 13 TeV recorded by the ATLAS detector that correspo
Robot failures in Human-Robot Interaction (HRI), though often stemming from technical limitations, can have severe effects on the interactional dynamics between humans and robots. Prior empirical research has led to conflicting findings on how such failures influence user perceptions and the overall success of the interaction. In this study, we investigate how human participants respond to robot f
Breviates are anaerobic protists and among the closest unicellular relatives of animals and fungi, yet their ecology and metabolism remain poorly understood. In this thesis, I investigated the distribution, metabolic potential, and bacterial interactions of breviates in low-oxygen environments. Breviates rely on bacteria both as a food source and potentially as metabolic partners. Breviates are pr
Smart cities and communities (SCC) constitute a new paradigm in urban development. SCC ideate a data-centered society aimed at improving efficiency by automating and optimizing activities and utilities. Information and communication technology along with Internet of Things enables data collection and with the help of artificial intelligence (AI) situation awareness can be obtained to feed the SCC
The lack of standardization in patient-reported outcome measures (PROMs) has made measurement and comparison of quality of life (QoL) outcomes in research focused on obesity treatment challenging. This study reports on the results of the second and third global multidisciplinary Standardizing Quality of life measures in Obesity Treatment (S.Q.O.T.) consensus meetings, where a core set of PROMs to
In this work, we use a time-warping-based morphology variation index, dwPCATpe, computed between the peak and the end of the T-wave, and assess its association with the occurrence of ventricular fibrillation (VF) episodes (VF group) in ECG recordings from 20 pigs undergoing a 40-minute coronary occlusion. The dwPCATpe series was obtained by quantifying the morphological differences between the fin
Understanding the complexity of host immune responses to parasite infection requires controlled experiments that can inform observational field studies. Birds and their malaria parasites provide a useful model for understanding host-parasite relationships, but this model lacks a well-described experimental context for how hosts respond immunologically to infection. Here, ten canaries (Serinus cana
Context: Older people with multimorbidity are vulnerable and often suffer from conditions that produce a multiplicity of symptoms and a reduced health-related quality of life. Objectives: The aim of this study is to explore the experience of living with a high symptom burden from the perspective of older community-dwelling people with multi-morbidity. Method: A qualitative descriptive design with
How to improve the care of elderly patients with multi-morbidity, regardless of borders between medical specialities and professions, starting from the patients' point of view and ending with a powerful policy document with impact on the political system. A document written by the Swedish Association of Geriatric Medicine, the Swedish Association of General Practice and the Swedish Association of
To optimise district heating (DH) systems and simplify the transition towards the fourth generation of district heating, it is important to remove any bottlenecks existing in the DH network. DH bottlenecks are in this study defined as pipes with too high flow relative to the pipe diameter, resulting in difficulties to maintain sufficient differential pressure in the area beyond the pipe. The aim o
Digital anamorphosis is used to define a distorted image of health and care that may be viewed correctly using digital tools and strategies. MASK digital anamorphosis represents the process used by MASK to develop the digital transformation of health and care in rhinitis. It strengthens the ARIA change management strategy in the prevention and management of airway disease. The MASK strategy is bas
Land use contributes to environmental change, but is also influenced by such changes. Climate and atmospheric carbon dioxide (CO2) levels’ changes alter agricultural crop productivity, plant water requirements and irrigation water availability. The global food system needs to respond and adapt to these changes, for example, by altering agricultural practices, including the crop types or intensity
Land-use and land-cover change (LULCC) represents one of the key drivers of global environmental change. However, the processes and drivers of anthropogenic land-use activity are still overly simplistically implemented in terrestrial biosphere models (TBMs). The published results of these models are used in major assessments of processes and impacts of global environmental change, such as the repo
This reviewe of Land Use Land Cover Change (LULCC) studies in Uganda indicate agriculture, forest, grassland, and woodland as the major land use and land cover types. Central Uganda is the most studied region (15%), followed by western (14), eastern (10), and northern Uganda (3). District scale studies were (48%), catchment (19%), forest (17%), national (10%), and park (7%). Landsat 30 m and remot
