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Lung diseases continue to present a large burden to public health, especially in industrialized countries. For abetter understanding of the underlying patho-mechanisms in lung related diseases as well as for testing theefficacy of novel therapies, preclinical studies in animal models are indispensable. The significance of preclinical X-ray based micro-computed tomography (µCT) research lies in its
Concrete is one of the most commonly used construction material on the earth after water. The compressive strength of concrete is an important parameter and is considered in all structural designs. Production of the cement is directly proportional to carbon emissions. The cement content in the concrete can be partially replaced with waste materials like steel fibers, silica fumes, etc. Calculating
Background Acute kidney injury (AKI) is a common and severe complication in patients treated at an Intensive Care Unit (ICU). The pathogenesis of AKI has been reported to involve hypoperfusion, diminished oxygenation, systemic inflammation, and damage by increased intracellular iron concentration. Hepcidin, a regulator of iron metabolism, has been shown to be associated with sepsis and septic shoc
The autonomy created for Åland in 1920 along with the linguistic and cultural guarantees stipulated in the 1921 Åland Agreement established Åland as a monolingual Swedish-speaking province within otherwise bilingual Finland. In particular, the Ålandic municipalities could themselves decide whether Finnish was to be taught in their primary schools. One hundred years later, Åland is still monolingua
Model Hamiltonians are regularly derived from first principles to describe correlated matter. However, the standard methods for this contain a number of largely unexplored approximations. For a strongly correlated impurity model system, here we carefully compare a standard downfolding technique with the best possible ground-truth estimates for charge-neutral excited-state energies and wave functio
Hexavalent chromium, Cr(VI), is classified as a Group 1 human carcinogen and causes lung cancer. This study was to investigate associations between occupational exposure to Cr(VI) and lung cancer-related non-coding RNAs.The study included 111 Cr(VI) exposed workers and 72 controls in Sweden, 91.4\smokers. Cr concentration in red blood cells (RBC-Cr) was measured. MicroRNA (miRNA) and long non-codi
This paper explores the dark gothic fantasy world of The Witcher 3: The Wild Hunt, an open-world video game from 2015. Using The Witcher 3 as a case study, the paper examines the moral dimensions of player interaction within the game beyond dialogue trees and NPC interaction. By investigating how the player is presented with monsters and animals within the game world, the paper makes an argument f
English is today learnt in multitudes of settings worldwide, making it difficult to characterize relationships between motivation and context in generalized terms (Ushioda 2013). In settings where students have extensive encounters with English outside school, a reluctance to invest effort in formal learning has been observed. To investigate ways in which out-of-school encounters impact on motivat
The embrace of coronavirus disease 2019 (COVID-19) vaccine conspiracies has been linked to vaccine hesitancy. This study aimed to investigate the relationship between COVID-19 vaccine conspiracy theories and perceived vaccine effectiveness. The study utilized a longitudinal follow-up study in which adults in Chile completed surveys in December 2020 (T1) and May 2021 (T2). The psychometric properti
Clinical axillary lymph node management in early breast cancer has evolved from being merely an aspect of surgical management and now includes the entire multidisciplinary team. The second edition of the “Lucerne Toolbox”, a multidisciplinary consortium of European cancer societies and patient representatives, addresses the challenges of clinical axillary lymph node management, from diagnosis to l
Introduction: Methylation analysis of the promoter region of tumor-suppressor genes has previously shown high sensitivity for detection of high-grade cervical intraepithelial neoplasia (CIN) and cancer. HPV-testing has a high sensitivity to identify women at risk to develop cancer, and has been implemented in cervical screening programs in several countries. But in most HPV-positive women the infe
While the political aspects of the interwar dystopias have received much attention, less focus has been given to the specific correlation to the economic thinking and developments of the period, in particular the prominence of economic planning. This article suggests that such a connection is significant by examining a key Swedish novel from the period, Kallocain, in relation to the early economic
The heavy-duty industry typically uses a high cetane fuel to power their vehicles, currently typically fossil diesel. Switching to renewable fuels such as methanol requires a major changeover in engine technology. Due to the high octane number of methanol, the diesel engines will have to be replaced by more suitable spark-ignited engines. An accurate knock control system will then be needed to acc
Background: Heart diseases are among the leading causes of disease burden worldwide with often a large impact on the lives of the affected individuals. The association between heart disease and depression is well-known and elevated suicide risk has been demonstrated in several types of heart disease. The aim of this study was to investigate what health care contacts individuals with heart disease
When we introduce transaction costs the perfect Black and Scholes hedge, consisting of the underlying stock and a risk free asset, becomes infinitely expensive. By loosening the pure arbitrage argument and only considering the expected transaction costs, one can find an upper bound on the price of an option. In this essay this is done by using a framework presented by Leland (1985) and Boyle and V
