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Mobile Performances : A Philosophical Account of Linguistic Undecidability as Possibility and Problem in the Theology of Religion

How to judge religions other than one's own when the means are lacking due to linguistic mobility? In the present thesis this question is mainly analysed in a Christian setting through a reading of the theologians Paul Knitter and Harold Netland. It is, however, claimed that the same question could be asked in other religious settings, also with regard to one's own tradition, and could be treated

Studies on Prostanoid Production in the Umbilicoplacental Circulation

The fetoplacental circulation is a low pressure system with a high vascular prostacyclin to thromboxane (Pc/Tx)synthesis ratio. In intrauterin growth restriction (IUGR) and diabetes the prostanoid balance may be altered. AIMS: To investigate relationships between umbilicoplacental vascular prostanoid synthesis (by incubation of vessel samples), circulatory changes (by Doppler velocimetry of umbili

Cyclic Nucleotide Phosphodiesterase 3B: Regulation in rat adipocytes and 3T3-L1 cells

Insulin stimulation of rat adipocytes results in phosphorylation and activation of the cyclic nucleotide phosphodiesterase 3B (PDE3B), a key enzyme in the antilipolytic signalling pathway of this hormone. In this thesis, the site phosphorylated in PDE3B upon stimulation of rat adipocytes with insulin and/or the beta-adrenergic agonist, isoproterenol is identified. In addition, upstream components

Stress-related peptides in suicide attempters

A suicide attempt is the best known predictor of completed suicide. It has long been assumed that most suicide attempts are the results of stress. The aim of this thesis was to examine some stress related peptides and their relations to the hypothalamic pituitary adrenal (HPA) axis, diagnoses and temperament in a heterogeneous group of suicide attempters shortly after a suicide attempt and at foll

Hormone-sensitive lipase: Molecular analyses of the human gene; structural and evolutionary aspects on expression, alternative splicing and cold adaptation

Hormone-sensitive lipase (HSL) is a key enzyme in adipose tissue that hydrolyses stored fat (triacylglycerol). The activity of HSL is under strict hormonal and neural control. Lipolytic agents, such as catecholamines, increase the cAMP levels, resulting in an activation of cAMP-dependent protein kinase (PKA), which in turn phosphorylates and activates HSL. This thesis describes the structural orga

Tissue kallikrein: pathophysiological role in acute pancreatitis

Tissue kallikrein releases pharmacollogically highly active kinins from kininogen. Many other enzymes may also release kinins. The aim of the study was to clarify the pathophysiological role of tissue kallikrein in acute pancreatitis. Two sensitive and specific radioimmunoassays for porcine and human tissue kallikrein were developed. A large release of tissue kallikrein from the pancreatic gland

Medborgarskap efter nationalstaten? : Ett konstruktivt förslag

This thesis is an attempt to formulate a constructive proposal for the ongoing establishment of a post-national European citizenship in the European Union. To the extent that the proposal is post-national, the ambition is to re-conceptualise the idea and ideal of citizenship in a new historical setting. To the extent that the proposal is constructive, the ambition is to develop and employ a method

IMPROVED SAFETY AND QUALITY OF CARE FOR PATIENTS WITH A HIP FRACTURE Intervention Audited by the National Quality Register RIKSHÖFT

Aim: Hip fractures are common and costly. The overall aim of this thesis was to explore how different clinical pathways influence safety and quality of care among patients with a hip fracture and to test the usefulness of the national quality register RIKSHÖFT as a working tool. The aim in paper I was to improve the outcome of patients with a hip fracture through optimized preoperative pain relief