The aim of the study presented in this report was to investigate what cues cyclists use to interpret the intention of motor vehicles (MVs) they interact with. This was done with help of on-site observations of cyclists’ interactions with motor vehicles (MV) at signalised intersections with different bicycle infrastructure facilities: A) no dedicated cycle facility, B) cycle lane and C) cycle path.The aim of the study presented in this report was to investigate what cues cyclists use to interpret the intention of motor vehicles (MVs) they interact with. This was done with help of on-site observations of cyclists’ interactions with motor vehicles (MV) at signalised intersections with different bicycle infrastructure facilities: A) no dedicated cycle facility, B) cycle lane and C) cycle path.

SummaryCancer is a multifactorial inheritance disorder caused by a combination of small variations in genes, often acting together with environmental factors. GWASs provide a potential method to investigate the genetic basis of such complex diseases, but they are limited to two main classes of cancer susceptibility variants with different levels of risk and prevalence in the general population: ra

The majority of the world’s peatlands are located in northern regions where climate change is occurring most rapidly. Therefore, there is an urgent need to understand whether, and under what conditions, peatlands will remain carbon sinks or become carbon sources. The uncertainties in our predictions stem from a variety of sources, including uncertainty about the competing effects of rising air tem

Växtätare kan påverka ekosystemprocesser, dels genom långsiktiga förändringar av växtsamhällets sammansättning, men också på kortare sikt genom derasmatspjälkning av organiskt material som cyklas genom markens nedbryderorganismer och tillbaka till de primära producenterna. Särskilt störreväxtätare har studerats i stor utsträckning, men i vissa ekosystem som skogar kan de mindre ryggradslösa växtätHerbivory can influence ecosystem processes, partly through long-term changes of the plant community compositions, but also more rapidly through the herbivores’ digestive alteration of the organic matter that is cycled through the soil and back to the primary producers. In the Subarctic mountain birch (Betula pubescens ssp. czerepanovii) forest (SMBF) in Northern Fennoscandia, outbreaks by the geo

The chemical industry is primarily dependent on fossil oil and gas as raw materials. With increasing demands on reducing the greenhouse gas emissions and carbon footprint attributed to fossil based production, the industry looks for alternative renewable cleaner resources to secure the supplies for future chemical and material products. The current trend in the shift to bio-based economy aims at u

Importance: Accurate blood-based biomarkers for Alzheimer disease (AD) might improve the diagnostic accuracy in primary care, referrals to memory clinics, and screenings for AD trials. Objective: To examine the accuracy of plasma β-amyloid (Aβ) and tau measured using fully automated assays together with other blood-based biomarkers to detect cerebral Aβ. Design, Setting, and Participants: Two pros

Background: Dietary advice remains the cornerstone of prevention and management of type 2 diabetes (T2D). However, understanding the efficacy of dietary interventions is confounded by the challenges inherent in assessing free living diet. Here we profiled dietary metabolites to investigate glycaemic deterioration and cardiometabolic risk in people at risk of or living with T2D. Methods: We analyse

Proposing “sustainable meetings”: convention bureaus marketing of destinations as ethicalIn the wake of a crisis and restrictions on physical interactions, the importance of meetings is emphasized more than ever. The meetings industry has gone from unprecedented down-sizing to higher booking rates than ever, and attracting meetings is an important part of municipalities place brandingstrategies. A

Aims: Estimation of prognosis in pulmonary arterial hypertension (PAH) has been influenced by that various risk stratification models use different numbers of prognostic parameters, as well as the lack of a comprehensive and time-saving risk assessment calculator. We therefore evaluated the various European Society of Cardiology (ESC)-/European Respiratory Society (ERS)-based three-and four-strata

Deciphering the metamorphic evolution of the roots of mountain belts is essential for understanding deep tectonic processes involved in mountain building. The Sveconorwegian orogen in southwestern Scandinavia, formed during the Rodinia assembly in the transition between the Mesoproterozoic and Neoproterozoic Eras, has been exhumed and provides access to interior deep structural levels of the ancie

Aims/hypothesis: The rapid remission of type 2 diabetes by a diet very low in energy correlates with a marked improvement in glucose-stimulated insulin secretion (GSIS), emphasising the role of beta cell dysfunction in the early stages of the disease. In search of novel mechanisms of beta cell dysfunction after long-term exposure to mild to severe glucotoxic conditions, we extensively characterise

BACKGROUND: Exercise and education is recommended as first-line treatment by evidence-based, international guidelines for low back pain (LBP). Despite consensus regarding the treatment, there is a gap between guidelines and what is offered to patients. Digital LBP treatments are an emerging way of delivering first-line treatment.OBJECTIVE: The aim of this study is to evaluate outcomes after partic

Background/Purpose: Rheumatoid arthritis (RA) is associated with an increased risk of cardiovascular disease (CVD). Systemic inflammation, driven by cytokines such as TNF, IL-6 and IL-17A, has been implicated as a contributing factor to CVD development in RA. The objective of this study was to investigate the impact of 92 inflammatory proteins on the risk of CVD events in patients with early RA.Me

Innovation has received widespread attention in research and in the business world because it plays a crucial role in organization survival and longevity. This especially rings true in the retail industry, as opportunities and challenges confront retailers due to the ongoing disruption of the industry. As retailers face increasing pressure to make innovation a strategic priority, and as major reta

Cyanobakterier är urgamla prokaryoter, som finns i en mängd olika livsmiljöer över hela världen. Deras förmåga att utföra fotosyntes (det vill säga att använda solljus, vatten och koldioxid för att producera syre- och kolhydrater) gör dem till viktiga primära producenter, och tillsammans med andra växtplankton utgör de basen för akvatiska näringsvävar.Vid optimala tillväxtförhållandena kan populatCyanobacterial blooms are increasing in occurrence and frequency world-wide, mainly due to eutrophication and increased water temperatures. In freshwater, Microcystis is one of the most common bloom-forming genera, renowned for producing the toxin microcystin which is harmful to humans and other mammals. The ability of Microcystis strains to produce microcystins is largely due to the presence or a

BackgroundCongenic leptin receptor deficient rat generated by introgression of the Koletsky leptin receptor mutation into BioBreeding Diabetes Resistant rat (BBDR.lepr−/−) is a novel animal model combining obesity, systemic insulin resistance and diabetes. Systemic insulin resistance is associated with reduced myocardial glucose utilization, but its effect on myocardial external efficiency, i.e. t

Semi-natural grasslands are characterized by high fine-scale plant species richness. The richest grassland communities, with many habitat-specialist species, are found in ancient grassland sites that have a long continuity of grazing management and low levels of soil nutrients. Grazed grasslands were widespread in the historical landscape. Agricultural intensification over the last two centuries h

The role of Apolipoprotein A-I (ApoA-I), the main protein component of HDL, in cholesterol transport and metabolism is well known and has been studied for more than four decades. More recently, ApoA-I protein has been shown to also have a positive role in glucose control by both stimulation of glucose uptake by muscles and by increasing glucose-stimulated pancreatic insulin secretion. Two of the f

Objective: To describe the short- and long-term outcomes of infants with early-onset fetal growth restriction (FGR) and umbilical artery absent or reversed end-diastolic flow (AREDF), delivered before 30 weeks' gestation and managed proactively. Methods: This was a retrospective cohort study of fetuses delivered for fetal indication before 30 completed weeks' gestation that had early-onset FGR (de

The purpose of this thesis is to add an astronomical component to the history and evolution of Earth by reconstructing the micrometeorite flux to Earth at different time intervals during the Phanerozoic Eon, using sediment-dispersed extraterrestrial spinel group minerals as a proxy. Chromite and chrome spinel are common refractory members of the spinel group, occurring in both extraterrestrial and