AbstractModern radiotherapy aims to treat the decease while minimizing the radiation dose to the adjacent normal tissue, to minimize acute and late effects of the treatment. The foremost technological approaches have been intensity modulated radiotherapy (IMRT) and intensity modulated proton therapy (IMPT) in combination with image guided radiotherapy (IGRT). IMRT and IMPT is characterized by a moModern radiotherapy aims to treat the decease while minimizing the radiation dose to the adjacent normal tissue, to minimize acute and late effects of the treatment. The foremost technological approaches have been intensity modulated radiotherapy (IMRT) and intensity modulated proton therapy (IMPT) in combination with image guided radiotherapy (IGRT). IMRT and IMPT is characterized by a more confo

Importance: Different brain regions appear to be involved during β-amyloid (Aβ) accumulation in Alzheimer disease (AD), but a longitudinally valid system to track Aβ stages in vivo using positron emission tomography (PET) is lacking. Objective: To construct a longitudinally valid in vivo staging system for AD using amyloid PET. Design, Setting, and Participants: Longitudinal multicenter cohort stu

Particulate air pollution is one of the major causes of premature death in the world, and combustion-derived soot emissions contribute strongly to the particulate pollution to which humans are exposed. Black carbon (BC) is one such emission and denotes soot with strong light absorption in the ultraviolet to infrared spectrum. Combustion can also generate brown carbon (BrC) particles, with absorpti

Rhythmic behaviors (in short RBs), such as applauding, dancing or rocking a baby to sleep are part of humans everyday life. Recently there has been a growing interest in the RBs of other species, as a way of tracking the evolutionary roots of human musicality. RBs have been initially studied in arthropods, insects, anurans and songbirds, where a single behaviour is tied to reproductive function. E

Compound input from genetic predisposition, environmental factors and lifestyle lead to beta-cell dysfunction which initiates the development of type 2 diabetes. Understanding the linkage between the environmental input and gene regulatory pathways controlling beta-cell function is key for developing novel therapies against T2D. The pancreatic beta-cell is controlled by ion channels. Voltage-gated

Bröstcancer är vanligt förekommande bland kvinnor, en av tio kvinnor får en bröstcancerdiagnos under sin livstid. Upplevelsen av bröstcancer är en komplex process, som innebär ett flertal sammanlänkade stressfulla händelser. Det är därför tydligt att sättet personen reagerar på sådana stressorer kan ha en betydande påverkan på både fysisk och psykisk hälsa. Resiliens är ett konstrukt som innefattaBreast cancer is a common event among women, one in ten women receiving a breast cancer diagnosis in their lifetime. The experience of breast cancer is a complex process that entails a multitude of interlinked potentially highly stressful events. It is thus evident that the manner in which one reacts to such stressors can have a substantial impact on both physical and mental health. Resilience is

Dual-mobility cups in THA were designed to reduce prosthesis instability and the subsequent risk of revision surgery in high-risk patients, such as those with hip fractures. However, there are limited data from clinical studies reporting a revision benefit of dual-mobility over conventional THA. Collaboration between anthroplasty registries provides an opportunity to describe international practic

Aims/hypothesis: Using a targeted proteomics approach, we aimed to identify and validate circulating proteins associated with impaired glucose metabolism (IGM) and type 2 diabetes in a Black South African cohort. In addition, we assessed sex-specific associations between the validated proteins and pathophysiological pathways of type 2 diabetes. Methods: This cross-sectional study included Black So

Att minska energiförbrukningens klimatpåverkan handlar om att göra energieffektiviseringar och att ersätta fossil energi med icke-fossil. Olika icke-fossila energilösningar ger olika klimatpåverkan sett ur ett livscykelperspektiv, och därför är valet av icke-fossila energilösningar av betydelse för klimatet. Biogas kan användas både för värme- och elproduktion samt som drivmedel. Detta examensarbeReducing climate impact from energy consumption is a matter of improving energy efficiency and replacing fossil energy with non-fossil. Different non-fossil energy alternatives cause different climate impact in a life-cycle perspective and, therefore, the choices between non-fossil energy alternatives have an impact on the climate performance. Biogas can be used for both heat- and electricity prod

By the mid-19th century, syphilis had been established for several hundred years as a disease associated with immorality, from which the poor in particular suffered. Although hospitals for the treatment of venereal diseases existed in most European countries, there would be no cure for another hundred years, and physicians battled unsuccessfully against disfigurement and death. The lock hospital i

I samband med äktenskapsskillnad kan frågan om nyttjanderättsersättning aktualiseras om en av makarna tillsvidare bor kvar i en tidigare gemensam bostad. Då det i svensk rätt saknas lagstadgande om nyttjanderättsersättning syftar denna framställning till att klargöra rättsläget, genom att analysera framförallt praxis och doktrin. Avslutningsvis syftar framställningen till att diskutera om tillämpn

I Sverige finns en lång tradition av att bygga småhus i trä. År 2022 beräknas det byggas ca 15 000 småhus varav den absoluta majoriteten byggs i trä. Att bygga mer i trä är något som eftersträvas då det är betydligt mer klimatvänligt än andra material. För att bygga tak används oftast prefabricerade takstolar där råspont eller plywoodskivor används som undertak. Det finns ofta inget extra system f

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