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Eukaryotic translation initiation factor 3 subunit e controls intracellular calcium homeostasis by regulation of cav1.2 surface expression.

Inappropriate surface expression of voltage-gated Ca(2+)channels (CaV) in pancreatic ß-cells may contribute to the development of type 2 diabetes. First, failure to increase intracellular Ca(2+) concentrations at the sites of exocytosis impedes insulin release. Furthermore, excessive Ca(2+) influx may trigger cytotoxic effects. The regulation of surface expression of CaV channels in the pancreatic

Ten-year risk of osteoporotic fracture and the effect of risk factors on screening strategies

Bone mineral density (BMD) measurements are widely used to estimate the risk of osteoporotic fractures. In addition, many other risk factors have been identified, sonic of which are known to add to the risk independently of BMD measurements. The combination of BMD with such risk factors increases the gradient of risk/standard deviation (SD) than that achieved by BMD alone. In this paper, we report

Mobility Management: Sustainability Option for Sofia's Urban Transport Policy? Learning from the experience of Lund and exploring its transferability to Sofia

This paper addresses the problem of urban transport management in Sofia ? the capital city of Bulgaria. It highlights the tensions and contradictions in the current policy and practice and suggests that the adoption of mobility management in policy making would elevate municipal capacity to deal with complex transport-environment conflicts and set the framework for a sustainable development of the

Assessing materials from an environmental perspective: Designing a material selection tool for the product development process of an organisation: How to adapt the tool to a company's conditions and needs?

The overall environmental impact of a product is influenced by decisions made during product development, e.g. on alternative materials. Different tools exist on how to select materials. However they are seldom adapted to a company's needs. The research question of this thesis is dedicated to this issue: Designing a material selection tool for the product development process of an organisation

Transparency of Executive Directors'' Remuneration

Following rising remuneration levels, significant owner reactions to excessive executive pay, and a request for more executive accountability, there has been increased focus on disclosure of more complete information on the pay levels, program structure and performance criteria for key executives in most European markets. In general, the academic research in the area has been about the conformance

Remburser - Korrespondentbankens kontraktsrelation med köparen och säljaren

Letters of credit is an instrument of payment that is frequently used in international trade. Normally the buyer engage a bank which irrevocably promise to pay the seller when the seller (beneficiary) present a specific set of documents. The document’s purpose is to prove that the seller has fulfilled the obligation in the underlying contract of sale. The bank’s task is to investigate the document