Filetype
BACKGROUND: The frequency of central venous catheter (CVC) related complications in hematological patients has previously been studied but some uncertainty remains. Therefore, this observational cohort study was designed primarily to investigate mechanical and infectious complications related to CVC insertion in hematological patients and secondarily, to identify factors associated with these comp
“Wet” eldercare facilities for people who age with long-term substance use problems and complex needs exist in several countries. Residents are accepted as active users of alcohol and drugs, and while the media has presented the permissive policies of the facilities in a positive light, others have described these policies as harmful. The aim of this article is to analyze residents' and staff memb
For successful climate change adaptation, the distribution of responsibility within society is an important question. While the literature highlights the need for involving both public and private actors, little is still known of how citizens perceive their own and others’ responsibility, let alone the moral groundings for such perceptions. In this paper, we report the results of a survey regardin
Glycemic traits are used to diagnose and monitor type 2 diabetes and cardiometabolic health. To date, most genetic studies of glycemic traits have focused on individuals of European ancestry. Here we aggregated genome-wide association studies comprising up to 281,416 individuals without diabetes (30% non-European ancestry) for whom fasting glucose, 2-h glucose after an oral glucose challenge, glyc
The structural transformation of retail is challenging for many small cities. Rather than seeing the retailer as a sole player, this article considers retail in small cities to be shaped in a retail eco system consisting of many different actors besides retailers such as municipalities, landlords, business/city organisations, customers/citizens. The key contribution of the article is to provide ne
Diabetes is a complex and multifactorial disease that affects millions of people worldwide, reducing the quality of life significantly, and results in grave consequences for our health care system. In type 2 diabetes (T2D), the lack of β-cell compensatory mechanisms overcoming peripherally developed insulin resistance is a paramount factor leading to disturbed blood glucose levels and lipid metabo
In the last few years, the traditional analysis of know as a factive verb has been lively debated by linguists and philosophers of language: several scholars have pointed out that know may be used non-factively in ordinary language. The aim of the present study is to expand this inquiry to other cognitive factive verbs than know, such as discover, realize, etc., and to investigate cross-linguistic
Cocaine- and amphetamine-regulated transcript (CART) is mostly known for its appetite regulating effects in the central nervous system. However, CART is also highly expressed in the peripheral nervous system as well as in certain endocrine cells. Our group has dedicated more than 20 years to understand the role of CART in the pancreatic islets and in this review we summarize what is known to date
This chapter discusses the value of a capability approach in historical research on older people. Historians are generally focused on studying continuity and change over time. Their research often aims at explaining how and why certain phenomena appear and take different shapes. Capability is a way of capturing an individual’s ability to live a meaningful life, or a life that they perceive as good
Background Lifestyle exposures play a major role in the development of disease, yet people vary in their susceptibility. A critical step towards precision medicine is identifying individuals who are resilient or sensitive to the environment, and, assess whether the allocation to these predicted groups are more or less likely to develop cardiometabolic disease.Methods We have used repeated data fro
Evidence of the impact of the COVID-19 pandemic on health behaviours in the general population is limited. In this retrospective longitudinal study including UK and US participants, we collected diet and lifestyle data pre-pandemic (896,286) and peri-pandemic (291,871) using a mobile health app, and we computed a bidirectional health behaviour disruption index. Disruption of health behaviour was h
Although many studies on mental health have been conducted among various populations during the COVID-19 pandemic, few studies have focused on post-traumatic growth (PTG) in the general population. The current study aimed to explore whether perceived social support, personality, and coping strategies are associated with PTG in the COVID-19 pandemic period. The study also investigated whether copin
Background: Co-occurring substance use disorders, and mental disorders are associated with significant suffering, high risks of violent reoffending and relapse in both substance use and psychotic episodes. Treatment for co-occurring substance use disorders in forensic mental health settings would benefit from incorporating patients’ understanding of their disorders. Method: Using an interpretative
Background: The recently launched high-throughput assays for detecting antibodies against SARS-CoV-2 has contributed to the managing strategies for the COVID-19 pandemic. This study aimed to investigate the performance of three high-throughput assays and one rapid lateral flow test relative to regulatory authorities' recommended criteria. Methods: A total of 315 samples, including 150 pre-pandemic
To meet future demands for cleaner water and comply with the revised Urban Wastewater Treatment Directive (UWWTD), many European wastewater treatment plants (WWTPs) will need quaternary treatment to reduce emissions of organic micropollutants (OMPs). Quaternary treatment based on granular activated carbon (GAC) is a promising solution, yet long-term, full-scale operational data remain scarce. This
