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The incidence and prevalence of heart failure (HF) has increased successively over the past decade. Mortality and morbidity is high. It is the most common cause of hospitalisation in the elderly and has been estimated to account for 1-3% of health care costs in many countries. There is a need therefore, to improve care for HF patients. However, due to limited economic resources, this must be done
Deep cuts in carbon emissions to avoid dangerous climatic change will require fundamental transformations of the energy and transport systems. This is an enormous challenge for society and the political system. In order to tackle this challenge, we argue that it will be necessary to develop new institutions and institutional practices that address and give priority to long-term climate policy obje
This thesis deals with how computationally effective lattice models could be used for inference of data with a continuous spatial index. The fundamental idea is to approximate a Gaussian field with a Gaussian Markov random field (GMRF) on a lattice. Using a bilinear interpolation at non-lattice locations we get a reasonable model also at non-lattice locations. We can thus exploit the computational
In order to define critical situations in which speed adaptation is unsatisfactory a number of traffic safety researchers from 20 countries were asked to rate the seriousness of various situations. The proportion of injury accidents in the different situations were also considered. Expert judgements, the high proportion of injury accidents and the increased accident risks compared to "normal" cond
Abstract in UndeterminedThe aim of this paper is to argue for the need of democratic control of expert committees generally and ethical expert committees specifically. Expert committees including ethical expert committees with the commission to give advice to political decision-makers are often criticized for not being democratic. This criticism point at different aspects of expert committees: com
The legislated goals for Master of Science in Engineering educations include goals like having the ability to critically, independently and creatively identify, formulate and handle complex problems as well as participate in research and development work and thus contribute to knowledge development. One might therefore argue that these educations are required to promote a deep approach to learning
In our experience, doctoral supervision seminars and training (and associated literature) focus the supervisor-student relationship to an extent largely leaving aspects of learning, enculturation and subject discipline aside. In 2006-2008 we therefore developed and implemented a 3-week programme compulsory for new primary research supervisors (docent degree) with a wider scope, at the faculties E
Queer/ed children and young people inhabit a space that seems nicely delineated by shamed biographies, fearful prospects and ignorance. In mainstream accounts, queer/ed children and young people are often un/represented through invisibility or drama, between exoticism and pity. ‘Children’ and notions of ‘the best interest of the child’ are used to dramatize and limit societal negotiations of sexua
BACKGROUND: Intracranial hemorrhage (ICH) is a potentially severe complication of endovascular thrombectomy (EVT). However, the relationship between the incidence and severity of ICH and vascular occlusion location is not well described.OBJECTIVE: To present a comprehensive analysis of subtypes of ICHs and their relationship to the occlusion site following EVT in the anterior circulation.METHODS:
The technical development of high-throughput sequencing technologies and the parallel development of targeted therapies in the last decade have enabled a transition from traditional medicine to personalized treatment and care. In this way, by using comprehensive genomic testing, more effective treatments with fewer side effects are provided to each patient—that is, precision or personalized medici
Knowledge about risks for overuse of psychoactive analgesics in patients having primary surgery for carpal tunnel syndrome (CTS) or ulnar nerve entrapment (UNE), or both, is limited. We investigated if patients with those nerve entrapment disorders have a higher risk of overuse of psychoactive analgesics (i.e., opioids and gabapentinoid drugs) before, after, and both before and after surgery than
Body-focused repetitive behavior disorders, including trichotillomania (hair-pulling disorder) and excoriation (skin picking) disorder, typically emerge in early adolescence, but little is known about the clinical characteristics and treatment outcomes of these disorders in young people, particularly in real-world clinical settings. Participants were 63 children and adolescents (51 girls; age rang
Most work implies the use of digital systems and tools, thus, digital technology plays a vital role in modern work environments. Even so, ergonomics and usability of IT systems and digital tools used at work are often weak, which causes work-related health problems including physical, visual, cognitive, and stress-related issues. We pose that one important reason for these types of issues is the l
In recent years, the need for affordable sustainable housing has increased. At the same time, there has been a gradual rising interest in compact living. With the mounting impacts of climate change, a new way of thinking is needed to develop more resilient and climate responsive ways of living that are compact, affordable, and climate-conscious. In response to this need, the idea of a ‘Z-Free Home
Stora företag i västvärlden har de senaste åren i ökad takt inkorporerat social rättvisa (jämställdhet, HBTQ+ rättigheter, rättvisa i rasfrågan) och miljörättvisa i deras marknadsföring och reklam. Modebranschen är en av de branscher som har använt sig särskilt mycket av social rättvise-symbolik. Denna avhandling fokuserar på artikulationer av miljö, genus, och ras genom en studie av hållbarhet ocThe corporatisation of social justice (gender justice, LGBTQI+ rights, racial justice) and environmental justice ideals in the last decades has grown immensely in western countries, exemplified by rainbow-clad ATM’s during Pride month or Nike using images of NFL player Kaepernick’s anti-racism protest action of taking a knee during the USA national anthem in a marketing campaign. One of the indust
Background: Over the past years, it has become clear that the microbial ecosystem in the gut has a profound capacity to interact with the host through the production of a wide range of bioactive metabolites. The microbially produced metabolite imidazole propionate (ImP) is clinically and mechanistically linked with insulin resistance and type 2 diabetes, but it is unclear how ImP is associated wit
