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Calcicole plant species are vulnerable to acidification and fertilization, caused by deposition and changes in land use, since they are adapted to nutrient-poor calcareous conditions. In this study we used vegetation data (vascular plants, bryophytes and lichens) from 1964 and 1985 and stored soil samples from 1966 to investigate long-term soil chemistry and vegetation changes in a semi-natural, s

Fossil soft-shelled turtles (Trionychidae) have so far been recognized in all continents except Antarctica, based largely on remains preserving their diagnostic sculptured shell bones. The origin of the group is generally assumed to be in the Early Cretaceous of Asia, whereas they first appear in North America and Europe during the Late Cretaceous and Paleocene, respectively. Here we describe the

On the European aggregate level there is an inverted-U curve for long-term energy intensity. In the 19th century aggregate European energy intensity rose, followed by a declining trend during the 20th century. This article discusses the possible explanations for the declining trend during the 20th century and explores the role of energy quality as expressed in energy prices. For the first time a c

Noncoding variants at human chromosome 9p21 near CDKN2A and CDKN2B are associated with type 2 diabetes(1-4), myocardial infarction(5-7), aneurysm(8), vertical cup disc ratio(9) and at least five cancers(10-16). Here we compare approaches to more comprehensively assess genetic variation in the region. We carried out targeted sequencing at high coverage in 47 individuals and compared the results to

Patients with functional gastrointestinal disorders express antibodies against gonadotropin-releasing hormone (GnRH) in serum. One common cause of posterior laryngitis (PL) is extra-esophageal reflux, but a functional etiology has also been suggested. The aim of this study was to scrutinize patients with PL with regard to the presence of GnRH antibodies and to examine the association between antib

This report describes a language and an interactive environment, called LICS, for implementation of control systems and dynamic modelling. It used graphics for representation of the structural properties: hierarchical decomposition, interconnection structure, and structure of the interfaces. The decomposition and interconnection structures are described by block diagrams. Low level modules are des

This thesis consists of four self-contained papers in applied microeconomics with family as a common theme. The first paper documents how the financial portfolios of parents change in response to the birth of a child. To identify dynamic effects around child birth, we use an event study approach with a matched treatment and control sample and a novel implementation of the same sex instrument. We f

This study assessed whether methods for capturing the pedestrian experience of outdoor lighting, previously evaluated in a full‐scale laboratory, were applicable in a real‐world setting. It applied an approach capturing the human response to outdoor lighting in a systematic way, by assessing perception, evaluation and behaviour in the lit environment. The study involved 81 participants from two ag

C-terminal α-amidation is the final and essential step in the biosynthesis of several peptide hormones. Peptidylglycine α-amidating monooxygenase (PAM) is the only known enzyme to catalyse this reaction. PAM amidating activity (AMA) is known to be present in human circulation, but its physiological role and significance as a clinical biomarker remains unclear. We developed a PAM-specific amidation