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The Impact of Ancestry and Common Genetic Variants on QT Interval in African Americans.

BACKGROUND: -Ethnic differences in cardiac arrhythmia incidence have been reported, with a particularly high incidence of sudden cardiac death (SCD) and low incidence of atrial fibrillation in individuals of African ancestry. We tested the hypotheses that African ancestry and common genetic variants are associated with prolonged duration of cardiac repolarization, a central pathophysiological dete

The genetics of diabetic complications.

The rising global prevalence of diabetes mellitus is accompanied by an increasing burden of morbidity and mortality that is attributable to the complications of chronic hyperglycaemia. These complications include blindness, renal failure and cardiovascular disease. Current therapeutic options for chronic hyperglycaemia reduce, but do not eradicate, the risk of these complications. Success in defin

Effects of a daily school based physical activity intervention program on muscle development in prepubertal girls.

This 12-month prospective controlled intervention evaluated the effect of a general school based physical activity program on muscle strength, physical performance and body composition in prepubertal girls. Fifty-three girls aged 7-9 years involved in a school based exercise program [40 min/day of general physical activity per school day (200 min/week)] were compared with 50 age-matched girls who

Consensual Approaches to Siting Controversy

Poor public perception can obstruct a construction project in a damaging way. Knowledge about public opinion should be considered as a relevant area of expertise for project managers and as an essential cost element in the planning and completion of construction projects. A consensual approach to a siting controversy requires informal face-to-face interaction among chosen representatives from all

Thaumasite sulphate attack on self-compacting concrete with limestone filler

The paper deals with durability of Self-Compacting Concrete with limestone filler during Thaumasite Sulphate Attack. For this purpose six concrete with varying amounts of limestone filler, particle size of limestone filler, pressure height during casting and mixing order were studied. One normal concrete (without limestone filler) with vibrator compaction was studied in parallel. In the ongoing ex

Evaluability : an alternative approach to polarity sensitivity

Based on Brandtler (2012), this paper argues that polarity items are sensitive to evaluability, a concept that refers to the possibility of accepting or rejecting an utterance as true in a communicative exchange. The main distinction is made between evaluable and non-evaluable utterances. The evaluable category comprises any clause that asserts, presupposes or entails the truth of an affirmative o

Utveckling av Byggnadsintegrerade Solenergisystem för Energieffektiva Hus

En solfångarhybrid har utvecklats och utvärderats på avdelningen för Energi och ByggnadsDesign på Lunds Tekniska Högskola, LTH. Solfångarhybriden, ”Solfönstret”, består av solcellslaminerade absorbatorer placerade i ett fönster bakom glasrutorna. Solfönstret finns byggt i ett enfamiljshus, Solgården, i Älvkarleö utanför Gävle. För att minska investeringskostnaderna för solel har reflektorer placer

Working with and Working on Corporate Social Responsibility: The Flexibility of a Management Concept

Why do some corporations become positioned as socially responsible and others as socially irresponsible? Here, an attempt is made to explore this issue. Within the established management literature it is held that managers do not understand corporate social responsibility (CSR), wherein the focus has been turned towards how corporations can work with CSR inside their organisation as a response to

Change in the use of diagnostic tests in the management of lower respiratory tract infections: a register-based study in primary care

Background Differentiating between pneumonia and acute bronchitis is often difficult in primary care. There is no consensus regarding clinical decision rules for pneumonia, and guidelines differ between countries. Use of diagnostic tests and change of management over time is not known. Aim To calculate the proportion of diagnostic tests in the management of lower respiratory tract infections (LRTI

Sustainable resource technology (SURETECH)

We all need to contribute to a more sustainable development – a fact that has become quite clear observing extreme weathers and diminishing fossil fuel sources. In line with the 12 Principles of Green Chemistry [1], (recommending the use of safer solvents, catalysed reactions, energy efficient processes and renewable feedstocks), research within the SuReTech program aims at developing technologies

Prediction of outcome after diagnosis of metachronous contralateral breast cancer.

BACKGROUND: Although 2-20% of breast cancer patients develop a contralateral breast cancer (CBC), prognosis after CBC is still debated. Using a unique patient cohort, we have investigated whether time interval to second breast cancer (BC2) and mode of detection are associated to prognosis. METHODS: Information on patient-, tumour-, treatment-characteristics, and outcome was abstracted from patien

Principles and Practices of Knowledge Creation: On the Organization of "Buzz" and "Pipelines" in Life Science Communities

This article links up with the debate in economic geography on "local buzz" and "global pipelines" as two distinct forms of interactive knowledge creation among firms and related actors and argues for a rethinking of the way social scientists should approach interactive knowledge creation. It highlights the importance of combining the insights from studies of clusters and innovation systems with a

Exploring the positioning of tobacco-free snus as a new category in the disruption of the market

Purpose: To explore the positioning of tobacco-free snus as a new category in the disruption of the market. Theory: Positioning, Disruption, Blue Ocean Strategy, New Category Creation Methodology: This paper uses a qualitative and exploratory research method. Primary data on the positioning of tobacco-free snus as a disruptive new category in the market was gathered through two semi-structured int