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Colorectal cancer is one of our most common malignancies and the second leading cause of cancer death worldwide. About 1/3 of the tumors are located in the rectum. Treatment advances such as the introduction of the standardized surgical technique total mesorectal excision (TME), pre-operative radiotherapy, and adjuvant chemotherapy have reduced the previously high local recurrence rates and improv
Hemp (Cannabis sativa) is an agricultural crop that can be used as a building material in combination with lime and cement. A composite building material that combines a cementitious binder (building limes and cement) with hemp shives, the woody core of the hemp stalk is generally referred to as hemp concrete (HC). However, industrial facilities to separate hemp shives and fibres are currently not
This thesis covers 12 years of experience in treating patients with congenital capillary malformations, so called port wine stains (PWS). The wide variation in treatment response to laser therapy has developed a profound need for the development of objective devises to measure treatment outcome, so that the maximum effectiveness of therapy can be achieved without unnecessary treatments. The purpos
Abstract The electrophysiological properties of insulin-secreting b-cells, glucagon-releasing a-cells and somatostation-producing d-cells in intact mouse pancreatic islets were investigated using the perforated patch whole-cell technique. It is demonstrated that it is possible to functionally identify the different cell types in situ. The ?-cells have a cell capacitance of 7.4 pF and differ from
The aim was to compare radiography of the tibiofemoral joint (TFJ) and the patellofemoral joint (PFJ), as well as bone scinigraphy with MR imaging in middle-aged individuals with chronic knee pain in the format of a prospective study of knee osteoarthritis. Individuals aged 35-54 years with chronic knee pain were identified. The prevalence of chronic knee pain was 15% (279/2000). Within this grou
The main problems in this thesis concern the impact of seasonal variations in daylight and ambient temperature on people's mood and the prevalence of various symptoms related to seasonal affective disorder. Questions are also raised about the role of the indoor environment and of the individual's personality as moderators of such an impact. In contrast to most previous research, the present study
Protein kinase C (PKC) is a serine/threonine kinase family with 10 identified isoforms. The contribution of PKC isoforms to cell growth and differentiation, with focus on neurite outgrowth, was investigated, using neuroblastoma and immortalised neural cells as model systems. In neuroblastoma cells one or several of the classical PKC isoforms are of importance for driving proliferation, protecting
I detta konferensbidrag beskriver jag ett exempel på hur IKT (Informations- och kommunikationsteknik) kan användas i litteraturundervisning på gymnasiet i Sverige på ett sätt som gör det möjligt för eleverna att bli mer aktiva producenter av kunskap i en flexibel inlärningsmiljö samtidigt som man främjar en globaliserad litteratursyn, särskilt vad gäller fransk litteratur, som går bortom nationens
The worldwide prevalence of obesity and type 2 diabetes is increasing rapidly. Both disorders depend on genetic and environmental factors. The studies included in this thesis investigated the possible association of the FOXC2 and CAPN10 genes with obesity, insulin resistance, type 2 diabetes, and related phenotypes. FOXC2 encodes a forkhead transcription factor, which was identified as a key regul
Objectives: To describe and compare the consumption of dairy products in cohorts included in the European Prospective Investigation into-Cancer and Nutrition (EPIC). Methods: Data from single 24-hour dietary recall interviews collected through a highly standardised computer-based program (EPIC-SOFT) in 27 redefined centres in 10 European countries between 1995 and 2000. From a total random sample
A presentation of The Nordic languages: An international handbook of the history of North Germanic languages (vol. 1 appeared in 2002, vol. 2 in 2005). Methodical and theoretical pluralism are graned to the contributors. The general organization and periodization of the work is discussed. An outline is given how the work was intended to handle synchrony vs. diachrony, language us vs. language syst
