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Att förstå svensk BRT: Jämförelse av bussprojekt genomförda 2014–2023 med inspiration från Bus Rapid Transit

Bus rapid trasit kan beskrivas som ett högkvalitativt bussystem med hög kapacitet, separerade körfält, signalprioritering och stationsliknande hållplatser. Det finns idag ingen tydlig definition vad svensk BRT är. Ett fenomen som är lätt att identifiera då alla svenska BRT-koncept skiljer sig markant åt mellan varandra. Men frågan är, vilken kvalitet håller svensk BRT och hur skiljer den sig mot i

De svenska turordningsreglerna i gråzonen?

Huvudsyftet med detta examensarbete är att utreda huruvida de svenska turordningsreglerna kan anses stå i strid med den svenska Diskrimineringslagen eller med EU-rätten. Vi har under uppsatsens gång identifierat grupper på arbetsmarknaden som vi anser befinna sig i riskgruppen för att bli utsatta för diskriminering vid tillämpningen av de svenska turordningsreglerna. Dessa grupper är bland annat y

Novel Agonists and Antagonists of Platelet Receptors

Platelets are central for the primary haemostatis. The platelet has surface bound receptors that are vital for the platelet activation. One of these receptors, the purinergic ADP-activated G-protein coupled receptor (GPCR) P2Y12 is a key receptor for platelet activation, and thus for thrombus formation, which makes P2Y12 a target in pharmaceutical antiplatelet therapies. As a complement during rev

Lung function in smokers - Aspects on COPD diagnosis and associations to atherosclerosis and alcohol consumption

Smoking is the most common and important risk factor for reduced lung function. Chronic Obstructive Pulmonary Disease (COPD) affects mainly smokers and is characterized by airflow obstruction, assessed using one of two major diagnostic spirometric criteria. Aspects of lung function besides spirometry in smokers fulfilling none, either or both of the spirometric criteria for COPD are not well known

Tectonic implications of ca. 1.45 Ga granitoid magmatism at the southwestern margin of the East European Craton

Between ca 1.53 and 1.40 Ga, the southwestern margin of the East European Craton was subjected to extensive magmatism and deformation. While various suites of anorthositic, mangeritic and charnockitic-granitic rocks were emplaced between ca. 1.53 and 1.50 Ga, a major event of A-type granitic magmatism took place around 1.45 Ga. During that event, numerous voluminous plutons were intruded in a wide

The influence of temperature on enzyme selectivity in organic media

The influence of different reaction parameters on enzyme selectivity was investigated. The reaction conditions studied were solvent dependence, water activity and reaction temperature. The improved selectivity was observed as higher synthetic yields in a-chymotrypsin and subtilisin catalyzed peptide synthesis respectively, and as higher enantioselectivity in the asymmetric reduction of ketones cat

Prenatal Diagnosis of Haemophilia - psychological, social and ethical aspects

The general aim of this study has been to study the psychological, social and ethical aspects for carriers of haemophilia and their spouses, related to the development of techniques for carrier testing and for prenatal diagnosis (PD) of haemophilia. This was investigated by a semi-structured follow-up interview with 29 carriers of haemophilia with experience of PD by fetal blood sampling (FBS), an

101 Women's patterns of daily occupations. Characteristics and realtionships to health and well-being

This thesis investigated the concept of balance in daily occupations. The overarching aim was to explore women’s patterns of everyday occupations and to investigate relationships between different aspects of patterns of daily occupations and health and well-being. The participants were working, cohabitant women with pre-school children. The methods used focused on exploring patterns of daily occup

Influence of Seed Particle Material, Preparation, and Dynamics on Nanowire Growth

Semiconducting nanowires have attracted scientific attention for more than 20 years due to their potential applications in electronic devices, as sensors, and in solid state lighting. These applications require high quality nanowires to begin with. Achieving such good control over the growth of nanowires is not trivial and requires profound understanding of the underlying processes. In this thesis

Diversity of CD1d-restricted natural killer T cells

The present study deals with natural killer (NK) T cells restricted to the antigen presenting molecule CD1d. NKT cells have been suggested to play a role in many diverse immunological situations such as clearance of different pathogens, protection against certain tumors, regulation of autoimmune reactions and as a link between innate and adaptive immune responses. NKT cells are in many respects un

Quality Control for high-throughput Quantitative Proteomics - Harnessing the potential of label-free LC-MS

Multiplex protein quantification, proteomics, is essential for uncovering new biomarkers and understanding biology. Liquid chromatography coupled to mass spectrometry (LC-MS) is the predominant technique for these measurements. In this thesis, optimization and quality control strategies for different phases of the LC-MS pipeline have been developed. Due to the inherent complexity and dynamic rang

A Theory of Architectural Objects to support Design Configuration

The thesis presents the results from a research project targeting architectural design and house-building in a setting of industrialized design process and product platforms. During the early stages of a traditional design process, architects manage a degree of problem complexity, besides technical aspects, also includes user function, material, environment, aesthetics etc. As a result of the des

Insulinogenic Effects of Milk- and Other Dietary Proteins, Mechanisms and metabolic implications

The metabolic syndrome (type 2 diabetes, obesity, hypertension, atherosclerotic cardiovascular disease, dyslipidaemia, and hyperinsulinaemia), is increasing in prevalence world-wide. The progression of this syndrome proceeds through a step-wise deterioration of metabolic events where deterioration of insulin sensitivity appears to have a key role in a ?vicious circle? of hyperinsulinaemia/hypergly

Automatic segmentation in CMR - Development and validation of algorithms for left ventricular function, myocardium at risk and myocardial infarction

In this thesis four new algorithms are presented for automatic segmentation in cardiovascular magnetic resonance (CMR); automatic segmentation of the left ventricle, myocardial infarction, and myocardium at risk in two different image types. All four algorithms were implemented in freely available software for image analysis and were validated against reference delineations with a low bias and hig

Samspel för förändring : En konsultationsmodell för arbete med elever i svårigheter

The primary aim of this thesis is to formulate a theoretically and empirically based consultation model for psychologists in school contexts. Ideas and strategies are clarified so that they can be applied, evaluated, and further developed by other professionals. The model has been constructed with an interactional approach, with the stress on patterns of interaction between grown-ups and children

A Catalytic and Mechanistic Investigation of Palladium-Phosphine Catalysed Aqueous Hydroxycarbonylation. Steric and Electronic Properties of the Ligands

The steric and electronic properties of eight water-soluble phosphines (1-8) were investigated by different methods. Phosphines 1-6 were tested as ligands in palladium catalysed hydroxycarbonylation of styrene. In line with the proposal that a ligand with low basicity should facilitate nucleophilic attack of water on the acyl complex, the electron rich {4 - [Bis(2 - diethylaminoethyl)] - aminobenz

Plasminogen and protein PAM: Interactions between streptococcal surface proteins and the human fibrinolytic system

Pathogenic bacteria often produce potent proteases capable of destroying host tissue thereby providing the bacteria with tools for spreading and nutrient access. This thesis describes how group A, C and G streptococci can acquire surface bound protease activity through an alternative mechanism, namely by binding and activation of the human protease precursor plasminogen. Group A streptococci of c