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Continuum based elasto-plastic-damage models for paperboard have been established in this work. The thesis begins with an introductory section that describes the mechanical properties of paperboard and some of the converting processes during forming of a package. A short review of modeling concepts that have been applied to paperboard is presented and then some key aspects and assumptions develope
Heat stress has been studied extensively. However, in the contemporary context of climate change there is a lack of information on the extent of future heat stress and its consequences, especially in occupational settings. The main aim of the research was to identify the current knowledge gaps by conducting a literature review (paper I) together with the collection of empirical data to examine the
The industrial use of biocatalysts is increasingly important in the production of e.g. pharmaceuticals, chemicals, fuels and foodstuffs. A successful biocatalytic process is dependent on many factors, such as the biocatalyst properties, the nature of the reaction, reactor type and downstream processing. This work is focused on two important issues: Immobilization of the biocatalyst and in situ pro
NADH:quinone oxidoreductase, or complex I, is a large, complex and poorly understood bioenergetic enzyme in the respiratory chain of living organisms. The enzyme has a conserved core structure, comprising fourteen protein subunits: Seven subunits protrude from the membrane and contain a flavin prosthetic group and eight iron-sulfur clusters that guide electrons from the oxidation of NADH towards t
The chain from hadron collisions to the physics results requires several important links. First the outcome of the collision is measured by the detectors. Then, the signal from the detector is processed and transformed into information relevant for the study of the physics processes. The data is made available to physicists to be analysed and used to improve theories. This thesis presents work don
The intestinal epithelium has the dual function of absorbing nutrients and water as well as being a barrier to potentially harmful substances such as macromolecules and bacteria. In the present thesis the barrier function of the intestinal mucosa was studied in vitro in Ussing diffusion chambers. Intestinal permeability to different-sized molecules was investigated and compared in various intesti
The purpose of this study was to investigate the role of protein kinases in peripheral nerve regeneration, with the use of dorsal root ganglia (DRG) and nodose ganglia explants from adult mice. The effects of neurotrophic factor stimulation and protein kinase inhibition were studied for long (days) and short term (minutes) effects. The protein kinase systems studied were protein kinase C (PKC), th
The work in thesis aims for artificial photosyntesis, which could and will mimic natural photosynthesis, the process that uses light to create energy rich compounds from H2O and CO2. Water is oxidized in Photosystem II (PSII) by the Water Oxidizing Complex (WOC), which is a catalytic site on the lumenal side of the thylakoid membrane. The chlorophyll complex P680 absorbs light and electrons are tr
Prostate cancer is one of the major causes of cancer related deaths in men in Europe and the United States. In this doctoral thesis, radioimmunoimaging and -therapy of prostate cancer was investigated pre-clinically by targeting the human kallikrein-related peptidase 2 (hK2) with radiolabelled monoclonal antibodies. hK2 is an antigen that is over-expressed in prostatic neoplasms and is closely rel
Accelerator mass spectrometry (AMS) is a highly sensitive method for counting atoms and it is used for detecting very low concentrations of both radionuclides and stable isotopes in small samples. The two major advantages of the AMS method are that the required amount of sample material is very small, but also that the efficiency is rather high, it takes less than an hour to analyse a sample. The
It it of great importance to increase the knowledge of various cell cycle kinetic parameters and the objective of this thesis is to use stochastic models to interpret Bromodeoxyuridine (BrdUrd) DNA Flow Cytometry (FCM) derived data in order to estimate such parameters. The cell cycle is the process of growth and division that is essential for an organism to increase in size. The cell cycle consist
During the last decades, coherent anti-Stokes Raman spectroscopy (CARS) has been an important tool in combustion research. The focus of this thesis is the improvement of the capability of the pure rotational CARS (RCARS) technique for this type of applications. The technique is used to measure temperatures and relative species concentrations in the gas phase and thermometry is performed by fitting
Emissions from anthropogenic combustion sources, such as light duty vehicles and small scale biomass combustion, contribute significantly to ambient aerosol particle concentrations both on local and global scales. These emissions have controlling impacts on public health and global climate. The overall aim of this thesis was to investigate how atmospheric transformation and combustion conditions a
The aim of this study is to examine the development of linguistic proficiency in written production of second-language French. In a longitudinal study of 30 months, we follow the written production of 5 guided learners of French as a second language. In order to apprehend proficiency we use the conventional parameters fluency, complexity and accuracy. The fluency and complexity are apprehended by
This thesis makes a contribution to strategy-proof social choice theory, in which one investigates the conditions under which it is possible to construct social choice functions (i.e., voting procedures) that can never be manipulated in the sense that some voter, by misrepresentation of his true preferences, can change the outcome of a voting and obtain an alternative he prefers to the one that ho
The objective of this thesis is to contribute to improved performance of district heating systems by focusing on three items. Item 1: Study of three methods for improving the performance of sub-systems within buildings connected to the distribution network. The methods can be considered as more or less innovative. Results from two of these measures are quantified in terms of so-called Primary Ener
In this thesis the focus is on crossing points in random fields and the probability distributions of various crossing variables in different applications. The crossing points are generalisations to random fields of points of level crossings by stochastic processes. Only crossing events that occur at distinct points in the parameter space are considered, for example stationary points (zero-crossing
This thesis consists of three essays on incomplete information in financial markets, two of which are theoretical, and one that is mainly of an empirical nature. All three essays concern parameter uncertainty, and they employ a continuous-time framework. The first essay, "The Effect of Information Quality on Optimal Portfolio Choice," analyzes the portfolio choices made by three types of agents,
Title. Contested streets. Political marches in Stockholm, 1887–1920.Abstract. Repertoires of contention change. It is clear that during the 19th and early 20th century, swedes learned to stage marches to make political claims, something that was virtually unknown in Sweden before the mid-19th century. At first, the oligarchy that held power in Sweden mostly accepted political marching in the stree
