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Abstract: The purpose of this thesis was to evaluate ProstaLund Feedback Treatment® (PLFT®) and the CoreTherm® device with regard to biophysics, mechanisms of action, treatment indications, additional techniques, efficacy and safety in the treatment of patients with benign prostatic hyperplasia (BPH). The application of two biophysical equations in the PLFT software is explained. The calculations
Politics induce economic agents to organise into special interest groups (SIGs) and act strategically to adjust their economic decisions and to conduct rent-seeking activities in order do improve the situation inflicted on them by policy. This thesis examines, in four essays, different forms of SIG influence on public policy in different institutional contexts. The two first essays examine two rel
Pathomechanisms of work-related myalgia are poorly understood. Myalgia is caused by exitation of nociceptors present in the muscular tissue but not in the muscle fibres themselves. Morphological analysis can contribute to knowledge of excitation of nociceptors. Surface EMG is a widely used method in the research field of ergonomics. Knowledge of influence of myalgia, occupation, age and intrinsic
The vertical distribution of the nutrient uptake of Norway spruce (Picea abies (L.) Karst.), European beech (Fagus sylvatica L.) and pedunculate oak (Quercus robur L.) has been investigated in southern Scandinavia. Two approaches were employed. The first involved estimation of the nutrient uptake capacity of the trees at different soil depths by determining the distributions of roots, external ect
In higher plants photosynthesis takes place in the chloroplast. This work focuses on two different processes that effects photosynthesis. Firstly, we studied the events occurring prior to the phosphorylation of LHCII. Secondly, we also studied two novel proteases, with the potential to degrade LHCII. In oxygenic photosynthesis two different photosystems partake in the gathering of light, PSI and
In recent years, awareness has grown of the necessity of understanding the inner world of refugees (in particular traumatized refugees), immigrants, and their children. These groups have come in increasing numbers to Scandinavia, and otherwise confident and capable professionals in all arenas of mental health, social work and other fields have often felt inadequate when working with them. After m
This thesis deals with different aspects of fatigue crack propagation in IN718. The ultimate objective of the work is to gain understanding of the fatigue process, from the macroscopic stress-strain relations to microscopic fatigue crack growth mechanisms. First, the stress-strain relations, which are fundamental in order to understand what the material encounter, are dealt with. The high temperat
Background - The effects of intervention can be evaluated in different ways, and objective measurements of changes in lung function are commonly used as the outcome measure. Patient-reported outcome (PRO) is an umbrella term used for all patient-based assessments. One important PRO is health-related quality of life (HRQL), which may be used as an evaluative or discriminative measure. Objectives -
The aim of this thesis is to explore discursive changes in conceptions of life course and ageing. In a sense the Life- Span embodies the boundaries of human existence, but furthermore, it symbolizes a discursive system with distinctive symbols and meaning, that regulates and re-construct a cultural context. Hence, a cultures notion of the Life-Span also reveals its images and apprehensions of agei
Both ovariectomy (OVX) and gastrectomy (GX) cause osteopenia in several animal species including humans. While the effect of OVX has been ascribed to estrogen deficiency, the underlying mechanism behind GX-induced osteopenia is poorly understood. Nutritional deficiencies, including lack of calcium and vitamin D, have been claimed to cause the osteopenia induced by GX. This thesis attempts to clari
Cardiovascular disease prevention has been a challenge for research for decades. The studies of this thesis were designed to investigate the role of health professionals in everyday clinical work based upon the concept of comprehensive primary care consultation. Routine check-up of blood pressure was the basis for the inclusion in an opportunistic screening for hyperchol-esterolaemia. Additionally
Shikimic acid production using recombinant E.coli has been developed during the past 15 years due to the increased demand of this product, primarily as a starting material for the anti-influensa medicine Tamiflu?. A detailed metabolic analysis of a shikimic acid producing E.coli strain was made in the current work in order to increase the understanding of shikimic acid production and identify mean
In this thesis mechanisms of neuronal damage were investigated in an experimental stroke model i.e focal ischemia. The influence of SD-induced calcium transients on neuronal damage were studied in animals with reduced energy supply. The influence of bioenergetic failure on K+e concentration and Ca2+e homeostasis were also investigated in transient focal ischemia. Moreover, the free radical formati
A new energy regime has recently become accessible in collisions at the Large Hadron Collider at CERN. Abundant in hadron collisions, the two-jet final state explores the structure of the constituents of matter and the possible emergence of new forces of nature, in the largest momentum transfer collisions produced. The results from searches for phenomena beyond the Standard Model in the dijet angu
The main scope of this thesis has been to study and develop new purification methods and also to further develop existing methods for purification to enhance their efficacy. Important parameters in the development of the methods are that they should be suitable for scale-up and possible to be integrated into recovery processes. The studies in this thesis describe that a hydrophobic peptide tag ca
Based on the discovery of a new amino acid transport system in Langerhans cells (LC), various aspects concerning the L-dopa uptake mechanism into human epidermal LC and the energy metabolism of epidermis have been examined and subsequently characterised. The system lacks any characteristics of other described amino acid transport systems in other cell types. The Falck/Hillarp histofluorescence met
Heat processing of vegetables involves the use of temperatures above the physiological limit which affect the cellular structures of the tissue and induce a series of events at cell level that will in turn be reflected in the transport properties of the tissue. One of the most important cellular structures from the mass transport point of view is the cell membrane since it represents the physical
The enzyme magnesium chelatase inserts magnesium into protoporphyrin IX (Proto) to produce to magnesium protoporphyrin IX, the first unique intermediate of the chlorophyll biosynthetic pathway. Magnesium chelatase is composed of three distinct proteins termed I (molecular weight ~40 kDa), D (~70 kDa) and H (~140 kDa). Defining the individual properties and structure of the magnesium chelatase comp
Lymphocytes are important mediators of adaptive immune responses. Naive T lymphocytes circulate in the blood and lymph between different secondary lymphoid organs in search for their specific antigen. Upon activation, lymphocytes change their expression of adhesion molecules and chemokine receptors and become able to enter non-lymphoid tissues where they take part in fighting infections. Selective
This thesis is a description of how knowledge of atomic physics can be used in a stellar spectrum analysis. Stellar investigations are spectroscopically performed based on wavelengths, intensities and spectral line structure. Properties such as isotopic shifts, hyperfine structure, Zeeman effect, line blending and spectral line broadening are investigated in stellar spectra to improve results of a
