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Cancer cells use normal cell signalling pathways in a proliferative fashion in order to prolong their own survival. Inhibition of one of the major signal proteins, STAT3 (Signal Transducer and Activator of Transcription 3) has previously been shown to induce apoptosis. Galiellalactone, a fungal metabolite, inhibits STAT3, thus presenting a potential lead for cancer treatment. The inhibition is bel
This thesis examine how farm-dwellers in the Mälaren region during the late Iron Age and early Middle Ages created, transferred, and preserved memory by deliberately placing new houses and graves on the houses and graves of previous generations. Focus is on memory as a social phenomenon and culture-specific resource created by these deliberate practices. The culture-specific element is oral cultur
Relining eller rörbyte – En jämförelse med LCA D A N I E L B E R G L U N D P A R A S T O U K H A R A Z M I S O F I I A M I L I U T E N K O F O L K E B J Ö R K T O V E M A L M Q V I S T | Rapport nr 2018:1 Re l in ing e l le r rörbyte – en jämföre l se med LCA 2 Sammanfattning Denna jämförande livscykelbedömning belyser tre huvudalternativ för renovering av avloppsrör; rörbyte, relining med rörfode
https://www.renoveringscentrum.lth.se/sites/renoveringscentrum.lth.se/files/2025-09/2018_1_Relining_eller_rorbyte.pdf - 2026-05-02
Nordic Network for Narratives in Medicine och Birgit Rausing Centrum för Medicinsk Humaniora bjuder in till konferens på temat Ranges of Proximity: Approaching Narratives in Medicine PLATS: LUX, Helgonavägen 3, Lund TID: Start kl. 13.00 den 3 oktober och avslutning ca kl. 14.30 den 4 oktober MÅLGRUPP: Studenter, forskare och praktiker inom humaniora, samhällsvetenskap, medicin, hälso- och sjukvård
https://www.medicine.lu.se/sites/medicine.lu.se/files/2022-08/Program%203-4%20okt_digital_FINAL.pdf - 2026-05-02
The aim of the dissertation is to elucidate Iron Age settlement in southern Halland from two angles: (1) the evidence of antiquities (graves), ground finds of metal and rock, and place-names; (2) the information conveyed by investigations in settlement archaeology. The combined study of graves, ground finds, and place-names shows that the image of southern Halland in the Iron Age differs depending
To deal with the wide dynamic rage necessary for a radio receiver or corresponding applications, but to avoid impractically high resolution at high data rates, the approach of using a floating-point analog-to-digital converter (FP-ADC) has been investigated. This approach de-links the dynamic range with the resolution, and a very wide dynamic range can be achieved by an ADC with a moderate resolut
The purpose of this thesis is to introduce the concept of distinctive competence in a multi-theoretical setting, consisting of the resource-based view, strategic human resource management and organizational learning, in order to develop a theoretical framework for better understanding of the dynamic side of distinctive competence. The empirical part of the study consists of an in-depth case study
En översikt över dagboksskrivandets och det självbiografiska skrivandets roll,typer och funktio under svenskt 1700-tal. Särskilt intresse ägnas den kristna traditionens betydelse för introspektion och subjektsuppfattning.
The protein folding and protein design problems are addressed, using coarse-grained models with only two types of amino acids, hydrophobic and hydrophilic. In addition to hydrophobicity forces, the models contain sequence-independent local interactions which are found to strongly influence the thermodynamics of these models. The models are studied using the dynamical-parameter Monte Carlo method.
Models for potein folding are developed and applied to peptides and small proteins with both α-helix and β-sheet structure. The energy functions, in which effective hydrophobicity forces and hydrogen bonds are taken to be the two central terms, are sequence-based and deliberately kept simple. The geometric representations of the protein chains are, by contrast, detailed and have torsion angles as
The main aim of my dissertation is to investigate som conceptions, power relations, and practices in the discourse of youth problems. I have studied some of the actors that are involved in the social constructing of the "juvenile delinquent" such as the police, the judical system, the social service, the media, the general public and last but not least, the young people themselves. The bulk of my
This treatise examines what I call the ‘traditional view’ on the phenomenology of dreaming. According to this view, dreams are experienced in more or less the same way as waking reality – that is, our experience of “being-in-the-dream” is very much like our experience of “being-in-the-world”. The traditional view will be examined from three different standpoints: phenomenology, cognitive science a
QCD at very high energies is still not very well understood. Difficulties arise from a strong non-linear dynamics and also from nonperturbative physics. Detailed analytic calculations are often only possible either for simple toy models, or for asymptotically high energies. In this thesis we investigate the high energy dynamics, with the goal of finding a realistic, working model for high energy Q
