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The work in this thesis has been focused on chondrocyte integrins and their interaction with the matrix proteins chondroadherin (CHAD) and collagen type II (CII). Affinity purification of CHAD-binding proteins from chondrocyte lysate, followed by immunoprecipitation of EDTA-eluted material identified alpha2beta1 as a CHAD-binding integrin. Interaction between alpha2beta1 and CHAD was found to prev

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The extracellular matrix (ECM) is a network of macromolecules which, together with cells, forms the various tissues of all metazoan organisms. Cartilage, in contrast to most other tissues, contains relatively few cells in proportion to the volume occupied by ECM. Part of this work involves investigation of cartilage ECM for expression and secretion of proteins that are considered to be the definin

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This thesis consists of four chapters where chapter 1 introduces the topics in the following chapters and discusses some related literature. Chapter 2 moves beyond the disability insurance with two types, able and disabled, in Parsons (1996). This is done in two ways: by introducing a third type, the partially disabled, and by allowing for a continuum of types. It is assumed throughout that the i

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What kind of public sphere is possible in the European Union? Against the backdrop of debates on the transformation of democracy beyond the nation-state, this study explores daily newspapers’ role in providing forums for transnational debate in the presumed absence of an overarching European collective identity. It uses empirical means to reconsider the question of the supposed co-constitutiveness

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Background: Elective knee and hip arthroplasty are common surgical procedures. Improved anaesthetic and nutritional care has the potential of increasing patient satisfaction and reducing length of hospital stay (LOS). The overall aim of this thesis was to evaluate the effect of perioperative nutrition and different anaesthetic techniques on per- and postoperative outcome after elective total hip (

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Parkinsons disease (PD) is a neurodegenerative disorder where dopaminergic neurons of the substantia nigra (SNc) in the mesencephalon are progressively eliminated. The ensuing loss of dopaminergic innervation of the basal ganglia manifests itself as severe motor deficits in PD patients. Clinical trials have shown that cell replacement therapy, where dopaminergic neuroblasts derived from fetal vent

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It has been shown that the present interglacial has been climatically dynamic with both rapid and severe climatic fluctuations. The spatial and temporal differences of these changes are however not fully resolved. The aim of this thesis is to present a detail high resolution record of past climate changes from the central South Atlantic. Peat and lacustrine sediment sequences were retrieved from

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Urban areas are geographically dispersed. There are built-in distances between housing, jobs and services. These distances call for mobility and fast means of conveyance. Society is dominated by and dependent on motoring. Cars have a negative impact on the environment and prognoses indicate an increase in the amount of travelling. The aim of this dissertation is to explain why travel behaviour wit

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This thesis consists of six articles on three different subjects in the area of complex analysis, operator theory and harmonic analysis. Part I - "The Shift Operator on Spaces of Vector-valued Analytic Functions" consists of three closely connected articles that investigate certain operators in the Cowen-Douglas class with spectrum D - the unit disc, or equivalently, the shift operator M_z

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Both presence and extent of myocardial infarction are important prognostic factors for mortality and quality of life in patients with ischemic heart disease. Thus, it is of great clinical importance to be able to diagnose and characterize myocardial infarction. One way to diagnose myocardial infarction is by using the 12-lead electrocardiogram(ECG). For estimation of infarct size and location from

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Thesis Purpose: The purpose of this study is to explore and develop an understanding of the rather unexplored phenomenon of using flagship stores in the FMCG industry. We want to explore what an FMCG flagship store is to understand why it is used in the context of strategic brand management. Moreover, we want to develop an understanding of how the brand experience might influence the consumer-bran

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This thesis used Feminist Critical Discourse Analysis to study femvertisements communicated by Social Media Influencers on Instagram. A critical perspective was adopted to study the convergence of advertising and feminism in the context of social media. The aim of the study was to explore the prevalent discourses of female empowerment, the main component in femvertising, and how existing discourse

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Digital tools in (zoo)archaeology have great potential for education, mediation, and research. Microphotogrammetric 3D-modeling offers new non-intrusive analytical approaches to old problems and questions. This thesis aimed to perform morphological differentiation between cut marks made from lithic and metal tool using qualitative and statistical quantitative approaches (Principal Component Analys

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Bakgrund - Soldat är ett tungt arbete där de anställda utsätts för stor belastning i stridsövningar och träningar med tung utrustning. Utrustningen har ökat i vikt under årens lopp och kan idag väga upp emot 50 kg. Vid besvär, skador eller smärta kan uppgifter som att marschera eller utrustningsbärande bli svårt. Höga siffror har uppmätts i tidigare studier, när det gäller på smärt- och skadeprobl

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Prior to resettlement, refugee children are exposed to stressors that leave them vulnerable to the development of health and psychosocial problems. The nature of these problems has been identified in numerous studies involving refugee children and their parents, yet relatively few studies have been carried out with workers from governmental and voluntary organizations. The primary aim of this stud

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Infectious diseases constitute a major global health problem. The presenting clinical picture results from a mixture of direct toxic actions by the microbiological agent and of the immune response mounted by the host. There is often a rapid onset, which may constitute a diagnostic and therapeutic challenge, whereas in other cases an extensive investigation over a long time period can fail to ident

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Bangladesh is one of the largest Muslim countries in the world. In spite of political turmoil, frequent natural disasters and widespread corruption it has, in less than four decades after its birth as an independent state, gained visible success in human development - especially the education of women and girls, family planning and health, and microcredit to the poor. As a Muslim country it has s

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The theory of stochastic time-frequency analysis of non-stationary random processes has mostly been developed for processes in continuous time. In practice however, random processes are observed, processed, and interpreted at a finite set of time points. For processes in continuous time, the ambiguity domain has interesting properties which makes it particularly useful. One such property is that t