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Inom kärnkraftsindustrin är säkerhet den aspekt som prioriteras högst. Alla kärnkraftverk är designade för att i högsta möjliga mån förhindra läckage av radioaktivetet till omgivningen, både under drift och i händelse av en allvarlig olycka. Med anledning av detta är reaktorinneslutningens vägg en av de viktigaste säkerhetsrelaterade konstruktionerna vid en anläggning, detta då denna konstruktionSafety is the top priority at a nuclear facility. The nuclear power plants are designed to prevent radioactive leakage to the surroundings, both during normal operation as well as in case of a severe accident. One of the most important structures in a nuclear power plant, with regard to safety, is thus the reactor containment wall. The containment wall is the last main barrier to prevent radioacti

Although bottom water hypoxia (O2 −1) is presently widespread in the Baltic Sea coastal zone, there is a lack of insight into past changes in bottom water oxygen in these areas on timescales of millennia, and the possible driving factors. Here, we present a sediment-based environmental reconstruction of surface water productivity, salinity and bottom water oxygen for the past 5400 years at Gåsfjär

The immune system has evolved through thousands of years and its architecture has challenged the medical field since the first hieroglyphs and will likely continue do so. With our co-evolution with millions of other species, the complexity to treat infectious diseases has been a race in increasing speed ever since. The establishment of penicillin shortened the length of that battle against a broad

Scientific summary: Ground settlement due to groundwater drainage during construction is important to be considered since ground settlement may cause severe building damages. The calculation of ground settlement contained several parameters with different magnitude of uncertainties. Thus a risk evaluation of ground settlement is necessary. The aim of this thesis was first to build a soil strata mo

This thesis investigates the importance of scale for power dynamics in the negotiation of risks connect-ed to Urban Rivers in Nairobi, Kenya. In addition to unequal distribution of wealth, global inequalities in the distribution of risk become increasingly important. Scale as a significant dimension of inequality is discussed in the context of Nairobi’s urban, as water scarcity and flooding events

Populärvetenskaplig sammanfattning: Naturbetesmarker är en av de miljöer som håller den hösta biologiska mångfalden i Sverige (Ingelög et al., 1993). Idag finns endast 10-12 % naturbetesmarker kvar (Jordbruksverket 2005a) av de 2 miljoner hektar som fanns i Sverige på mitten av 1800-talet (WWF, 2006). Naturbetesmarkerna innehar en speciell flora som är anpassad för kontinuerlig störning och näring

Augustenborg storm water system has become well known for its incorporation of urban green spaces. Open storm water system was developed in late 1990s by disconnecting impervious surfaces from combined sewers as a result of flooding problem in the basements after heavy rain events. The open storm water management system consists of open channels and ponds, a small wetland, green infiltration areas

Den Nagssugtoqidiska orogenen är ett cirka 300 km brett Paleoproterozoiskt deformerat och metamorfaserat bälte som sträcker sig över de södra och mellersta delarna av västra Grönland. Bergarterna karaktäriseras och domineras av metamorf arkeisk ortognejs och en mindre del suprakrustala sekvenser, där metasediment finns representerade. Trots sin ringa omfattning utgör de suprakrustala sekvenserna eThe Nagssugtoqidian Orogen is represented by an approximately 300 km wide Palaeoproterozoic deformation and metamorphic belt that stretch through the southern and middle parts of west Greenland. The Orogen is characterized and dominated by metamorphosed Archaean orthogneisses with minor supracrustal sequences. Despite its small extent the supracrustal sequences are an important factor in the inter

Considering the growth in urbanization, leading to an increase in impervious surfaces, and the changing climate, enhancing the intensity and frequency of rainfall events, existing urban drainage networks—separate or combined sewer systems—are presumed to face substantially elevated hydraulic loads, causing pluvial floods in urban areas. There are several ways to address these challenges. Cities ca

1. Neuropeptide Y (NPY) and peptide YY (PYY) act at receptors referred to as Y1 and Y2, while the Y3 receptor is specific to NPY and does not recognize PYY. The effects of NPY, its related peptides and a series of newly constructed chimeric NPY-PYY peptides were examined on excitatory and inhibitory postsynaptic currents (e.p.s.cs and i.p.s.cs, respectively) in rat dorsomedial nucleus tractus soli

An extended version of a numerical model introduced by Larson et al. (2013) to simulate long-term cross shore material exchange for the subaqueous portion of the profile has been developed. Efforts have focused on improving the model to better account for beach systems consisting of two bars (inner and outer bar), as well as simulating the feeder response over time of nearshore dredged material ba

PURPOSE: The R2Pulm trial was conducted to evaluate the effect of busulfan-melphalan high-dose chemotherapy with autologous stem-cell rescue (BuMel) without whole-lung irradiation (WLI) on event-free survival (main end point) and overall survival, compared with standard chemotherapy with WLI in Ewing sarcoma (ES) presenting with pulmonary and/or pleural metastases. METHODS: From 2000 to 2015, we e

Microstructure and crystallographic texture are the key factors that determine the properties of sputtering target used in integrated circuit fabrication. Multi-pass clock-rolling has been used recently to produce Ta sputtering targets. However, the effect of strain per pass, or the number of passes to achieve desired thickness, in clock-rolling on the homogeneity of final microstructure has not b

Accurately quantifying soil base cation pool sizes is essential to interpreting the sustainability of forest harvests from element mass-balance studies. The soil-exchangeable pool is classically viewed as the bank of "available" base cations in the soil, withdrawn upon by plant uptake and leaching and refilled by litter decomposition, atmospheric deposition and mineral weathering. The operational

Despite advances in the treatment quality of HIV throughout the world, several countries are still facing numerous obstacles in delivering HIV treatment at a sufficiently high quality, putting patients' lives in jeopardy. The aim of this status article is to give an overview of HIV treatment outcomes in the West African country, Guinea-Bissau, and to assess how newer treatment strategies such as l

Popular Abstract in Swedish Mikroorganismer finns överallt! De klarar av att överleva i extrema miljöer, extrema pH, extrema temperaturer och kan motstå strålning och gift i doser som vi inte skulle överleva. Framförallt klarar mikroorganismer av att överleva i en specifik extrem miljö - människan. Hundratals olika mikroorganismer bor på och i oss, i ett antal som långt överskrider vårt eget cellaMicroorganisms are everywhere! They can tolerate many diverse extreme environments, such as the human body. Even though many of us might associate the word microorganism with infections and disease, most are actually either harmless or even beneficial for us. Those commensals often fight off more dangerous bacteria and might also directly benefit their host. The human skin harbors several differen

Stem cells have qualities that clearly distinguish them from all other cells. Capabilities like self-renewal, differentiation and migration make them truly powerful. This thesis deals with different aspects of stem/progenitor cells in relation to cancer. Certain types of neural progenitor cells (NPCs) have been shown to possess a potential of tracking glioma cells in the brain. This makes them pot