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Over a decade ago, the concept of objectively evaluating the performance of control strategies by simulating them using a standard model implementation was introduced for activated sludge wastewater treatment plants. The resulting Benchmark Simulation Model No 1 (BSM1) has been the basis for a significant new development that is reported on here: Rather than only evaluating control strategies at t

Popular Abstract in Swedish Som en blixt från klar himmel drabbas en ung, och till synes frisk person, av hjärnblödning. Denna stroke leder till demens och efterföljande nya blödningar leder slutligen till en för tidig död. Man har kunnat visa att denna sjukdom beror på att en variant av ett visst protein, cystatin C, tvinnar ihop sig till rep-liknande långa fibriller. Dessa fibriller ansamlas sedAmyloidosis is a group of diseases characterized by a change in protein conformation resulting in aggregation and tissue deposition of amyloid fibrils. One variant of cystatin C, L68Q cystatin C, is highly amyloidogenic and persons carrying the corresponding gene suffer from massive cerebral amyloidosis leading to brain hemorrhage and death. Amyloidogenic proteins like cystatin C and prion protein

This thesis concerns the Large Eddy Simulation methodology and its application to predict complex turbulent flows at high Reynolds numbers, and at times also with high Mach numbers. The meaning of the word ?complex? refers both to the presence of complex flow phenomena and the, often, complex geometry of man-made devices restricting the flow. A fairly thorough evaluation study of the numerical met

An experimental study has been carried out to investigate the effects of Coriolis force and centrifugal buoyancy force on convective heat transfer in a smooth cooling channel under rotating condition in a new rotation facility. The main motivation behind this work is to obtain required data for developing heat transfer correlations based on rotating state. In accordance with the open literature, f

The structure of eleven complexes of cadmium-substituted alcohol dehydrogenase with or without coenzyme and with different non-protein cadmium ligands has been estimated by combined quantum chemical and molecular mechanical geometry optimisations. The geometry of the optimised complexes is similar to the crystal structure of cadmium-substituted alcohol dehydrogenase, indicating that the method beh

The local geology at Kloxåsen is characterised by ejecta deposits from the 458 Ma Lockne marine impact. The Kloxåsen ejecta are located on a Caledonian parautochthonous unit, approximately 7 km from the centre of the 7.5-km-wide Lockne crater structure. The ejecta were deposited on the seafloor and were covered with seawater immediately after the impact event. Of special interest is a mafic impact