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Performance of Fully Automated Plasma Assays as Screening Tests for Alzheimer Disease-Related β-Amyloid Status

Importance: Accurate blood-based biomarkers for Alzheimer disease (AD) might improve the diagnostic accuracy in primary care, referrals to memory clinics, and screenings for AD trials. Objective: To examine the accuracy of plasma β-amyloid (Aβ) and tau measured using fully automated assays together with other blood-based biomarkers to detect cerebral Aβ. Design, Setting, and Participants: Two pros

A groundwater flow model for water related damages on historic monuments – Case study West Luxor, Egypt

In 1979 “The Ancient Thebes and its Necropolis” entered in the World Heritage List in a core zone of 7390 ha. Western Thebes holds the remains of about 36 temples in varying degrees of preservation and dating from archaic times (3100 – 2686 B.C.) to the Greco-Roman Period (332 B.C. – 395 A.D.). The temples of Medinet Habu, Ramesseum and Sethos I, are located in the western side of modern Luxor and

Vägskyddssystem i Sverige - En jämförande studie av dagens och framtidens system för vägskyddsanläggningar

The railway makes an extensive barrier in the landscape. To lower the impact of this barrier, and to allow people to easily pass it, level crossings are implemented. A level crossing is an intersection in the same plane between railway and road. Here traffic of all sorts meet with railway vehicles, which is why level crossings are one of the most distinct points of conflict in the entire railway s

Evaluating the role of DNAJ chaperones on PolyQ aggregation in PolyQ expressing HEK293 cell lines using CRISPR-dCas9 knock-down

Guardian proteins help or hinder clumpy proteins? Proteins are products encoded by DNA in cells. They need to be folded in a certain structure to perform their function in the cell. Because of this, the proteins need a quality control system to ensure that they are folded correctly. A large group of proteins called as chaperones are important in this regard. The main role of chaperones is to fold

Egyptology in the Periphery. Valdemar Schmidt and the making of Egyptology in Denmark 1872–1925

Egyptology in the 19th and early 20th centuries developed simultaneously with increased imperial presence in Egypt by the European imperial powers, which would have influence on how the discipline was practised. The history of Egyptology has for this reason primarily focused on the big four – Great Britain, France, Germany and USA – and on Egypt itself. The aim of this study is to examine how Egyp

Development of a vitamin C-rich baobab beverage

It is challenging for the food industry to deliver products that satisfy consumers changing desires and needs. Baobab is a fruit that holds potential for the development of trendy food products due to its rich nutritional profile and unique rheology. Unlike most fruits, it contains a dry pulp with a moisture content of 11-12 % (Phytotrade, 2008). Despite these features, baobab has been overlooked

En komparativ jämförelse mellan svensk och engelsk rätt - föräldrasamverkans utformning

Sammanfattning I Sverige råder ett strikt krav på konsensus när det gäller beslutanderätten vid gemensam vårdnad av barn. Detta innebär att vårdnadshavarna tvingas komma överens om princip alla frågor med undantag för den dagliga omsorgen vad gäller barnet. När vårdnadshavarna inte längre bor tillsammans efter exempel- vis en äktenskapsskillnad, finns samma samstämmighet dem emellan kanske inte lSummary In Swedish law, joint legal custody generally entails a strict requirement of con- sensus in decisions concerning the child. The basic precondition is that both parents must agree on almost all matters. An exeption from this condition can however be made in matters concerning the daily care. The housing parent has in these matters autonomy to decide. After for example a divorce, it can of

Surface Modification of LDPE Layers Using Low Temperature Plasma For Enabling Adhesion Measurements

For the juice package to protect and keep your juice fresh it is important that the different layers in the packaging material sticks very well together. The ability for two things to stick together is called adhesion. For the people that create juice packages, this is important to measure so that the packages don’t leak. This measurement has turned out to be very tricky, but this study has shown

Identification of novel phage resistance mechanisms in Campylobacter jejuni NCTC 12662

Bacteria-eating viruses and their prey: an eternal war The antibiotic resistance problem: what if bacterial viruses were the solution? Nowadays, we hear more and more dreadful stories about nasty bacteria becoming resistant to our best antibiotics. Researchers are therefore spending much time trying to think of alternatives, one of which could be the use of bacteriophages -literally meaning bact

Är kommunernas avkastning från dess bostadsaktiebolag marknadsmässig? - En kartläggning och jämförelse över perioden 2011–2018

De kommunala bostadsaktiebolagen, tillsammans med vissa stiftelser, är vad som utgör Sveriges allmännytta och är ett av kommunernas viktigaste verktyg för att främja bostadsmarknaden. Allmännyttan regleras av lagen (SFS 2010:879) om allmännyttiga kommunala bostadsaktiebolag, förkortad Allbolagen. Bolagen ska i allmännyttigt syfte främja bostadsförsörjningen i kommunen genom att erbjuda goda hyresbReal estate companies owned by Swedish municipalities, together with certain foundations, constitute what we call Allmännyttan. Allmännyttan is one of our municipalities’ most important tools for promoting public housing and is regulated by the law, abbreviated Allbolagen (SFS 2010:879). For purposes of public benefits, the municipal real estate companies are obliged to promote housing supply in t

Har svensk rätt drabbats av tillfällig sinnesförvirring? - En studie av hur skuldprövningen påverkas av tillståndet

Om den tilltalade inte har förstått innebörden av sin gärning och inte har kunnat anpassa sitt handlande därefter, anses personen vara otillräknelig. I de flesta andra rättsordningar innebär det att den tilltalade inte kan dömas för brott, men svensk rätt saknar ett krav på tillräknelighet sedan brottsbalken trädde i kraft 1965. Sverige intar en särställning genom att samtliga kan bli föremål för If the defendant has not understood the meaning of their act and has not been able to adapt their actions accordingly, the person is deemed legally non-imputable. In most other legal systems, this means that the defendant cannot be liable, but since the Criminal Code entered into force 1965, Swedish law lacks a demand for imputability. Sweden has a peculiar regulation on the matters and everyone c

Defining Regulators of Human Hematopoietic Stem Cells

Bone marrow transplantation (BMT) is a conceptual and elegant example of stem cell therapy, rendered possible by the dual capacity of hematopoietic stem cells (HSCs) to self-renew and differentiate. These defining features ultimately ensure the production of all blood cell lineages and simultaneous maintenance of the stem cell pool, thereby maintaining lifelong homeostasis. Banked umbilical cord b

Vibration Analysis of Underground Tunnel at High-Tech Facility

Max-lab is a national laboratory operated jointly by the Swedish Research Council and Lund University. Nowadays, the Max project consist of three facilities (three storage rings): MAX I, MAX II, MAX III and one electron pre-accelerator called Max Injector. A new storage ring is needed due to improved nanotechnology. MAX IV is planned to be the next generation Swedish synchrotron radiation facilit

Distribution of dialysis fluids - Is transport and storage optimised from a temperature point of view?

The background to this thesis is the fact that high temperature during transport and storage, degrade the glucose of peritoneal dialysis fluid (PD-fluid), into a toxic substance. Research at Gambro has shown that exposure to high temperatures can destroy the PD-fluid in just a few hours, requiring months to repair. With this knowledge it became important to monitor the temperature, and evaluate wh

How can the business potential of products with health claims increase? - A case study of PrimaLiv

The purpose of this master thesis is to investigate the influencing factors of the busi-ness potential of products with health claims, using PrimaLiv as an example, and give recommendations on how a dairy producer, which is present in the Swedish market, could improve the sales rates of products with health claims. We have chosen to put a main focus on the consumers, since they determine the busin

How can the business potential of products with health claims increase?

The purpose of this master thesis is to investigate the influencing factors on the business potential of products with health claims, using PrimaLiv as an example. And to give recommendations on how a dairy producer, which is present in the Swedish market, could improve the sales rates of products with health claims. We have chosen to put a main focus on the consumer, as he or she determines the b

From Monte Carlo PET Simulations to Reconstructed Images : Modelling and Optimisation for 68Ga Theragnostics

In nuclear medicine, radiopharmaceuticals can be administered for both diagnostic and therapeutic purposes. In recent years, there has been an increasing interest in theragnostics, a strategy that combines both diagnosis and therapy. This can be achieved by using similar radiopharmaceuticals for imaging and radionuclide therapy, which enables highly personalised disease management. One theragnosti

Situating Faculty Development in the Clinical Workplace

Medical students’ access to clinical supervision when rotating through hospital workplaces and the quality of that supervision are and have been an area of growing professional and societal concern. Increased training measures targeted at supervising physicians have been suggested to address this issue. Traditionally, such training has focused on offering physicians opportunities to develop as sup

On Optimal Control for Concept Evaluation and System Development in Construction Machines

The main goal with this thesis is to develop a method to maximize the fuel efficiency [ton/l] in construction machines, while fulfilling the desired productivity [ton/h]. This is achieved by focusing on two of the main influencers; the machine concept evaluation and the development of operator assist systems. To be able to perform a concept evaluation that is unbiased from control engineering expe