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Aim: To develop a logistic regression model for discrimination between benign and malignant unilocular solid cysts with papillary projections but no other solid components, and to compare its diagnostic performance with that of subjective evaluation of ultrasound findings (subjective assessment), CA 125 and the risk of malignancy index (RMI). Methods: Among the 3511 adnexal masses in the Interna

The aim of this study was to develop an in-vitro release method suitable for injectable slow-release lipid formulations of local anaesthetics (or other drugs). We also aimed that the results of the in-vitro measurements should have a clear relationship to duration of action in-vivo. Six formulations of bupivacaine base in medium-chain triglyceride-glyceryl dilaurate mixtures were developed. A new

S-phase fraction (SPF), estimated in the flow cytometric DNA histogram, is a prognostic factor in breast cancer. There are, however, some inherent difficulties in the estimation of SPF, such as the influence of debris, aggregates, and normal cells. Most of the available SPF calculation principles try to consider these difficulties, but so far no consensus has been reached with regard to which prin

Cloud condensation nuclei counter (CCNC) measurements performed at 14 locations around the world within the European Integrated project on Aerosol Cloud Climate and Air Quality interactions (EUCAARI) framework have been analysed and discussed with respect to the cloud condensation nuclei (CCN) activation and hygroscopic properties of the atmospheric aerosol. The annual mean ratio of activated clou

Adsorption of uncharged homopolymers of various flexibilities in good solvent onto planar surfaces Lit various polymer-surface interaction strengths have been investigated by employing a coarse-grained bead-spring polymer model using simulation techniques. The polymer flexibility ranged from fully flexible to rod-like polymers, and the adsorption strength varied from weak to strong adsorption. Equ

Popular Abstract in Swedish Vid total höftledsartroplastik är cementering av den konstgjorda ledpannan (cupen) ett allmänt sett välfungerande koncept, men frekvensen av lossning och åtföljande omoperation är fortfarande för hög. En av de viktigaste faktorerna för långtidsöverlevnad av protesimplantat är den initialt uppnådda fixationen och stabiliteten. Den föreliggande avhandlingen omfattar såvälIn total hip arthroplasty cemented fixation of the acetabular component is a generally successful concept, but the rate of aseptic loosening and consequent revision surgery is still too high. One of the crucial factors for longterm implant survival is the initial fixation and stability. This thesis comprises experimental and clinical studies, including radiostereometry (RSA) with up to 5 years fol

Infectious pancreatic necrosis virus (IPNV) is a naked virus of an uncomplicated structure. In the interior part of the virion, the two segments of double-stranded RNA are located together with the minor structural protein VP1. This protein is detected in its free form as well as linked to the genome. A polymerase activity has been assigned for VP1. The localisation of the viral protein VP3 has a

Popular Abstract in Swedish Eftersom gamla träd har blivit mycket ovanligare de senaste 200 åren, både i skogslandskapet och på ängs- och hagmarker, har djur som lever i gamla träd blivit mycket sällsyntare och många arter är utrotningshotade. I gamla ekar bildas ofta mulm i stammarnas håligheter. Mulmen består av murket trämjöl och i den lever en rik och specialiserad fauna som framför allt utgörMany species associated with old trees are threatened, as this habitat has decreased severely in Europe during the last 200 years. In old oaks, hollows with wood mould often form in the trunks and these harbour a specialized fauna mainly consisting of beetles, flies and pseudoscorpions. This thesis contains the first quantitative examination of the habitat requirements and population ecology of sp

The emittances of the electron beams at the MAX-laboratory accelerator system have been studied. Apart from the build-up of the diagnostic tools for precise determination of the beam spatial profiles, the objectives have been: a) to verify the accelerator design emittances at low currents and to try to determine the emittances also at high currents; b) to investigate possibilities to manipulate th

Popular Abstract in English Polyhydroxybutyrate (PHB) is a homopolymer belonging to the family of biopolyesters, polyhydroxyalkanoates (PHA) produced by different bacteria and archaea as intracellular granules often under conditions of metabolic stress due to a limited supply of essential nutrients. The properties of the PHAs are similar to those of polyethylene and polypropylene and can hence repPolyhydroxybutyrate (PHB) is a homopolymer belonging to the family of biopolyesters, polyhydroxyalkanoates (PHA) produced by different bacteria and archaea as intracellular granules often under conditions of metabolic stress due to a limited supply of essential nutrients. The properties of the PHAs are similar to those of polyethylene and polypropylene and can hence replace these fossil based poly

A Holocene sediment sequence from Lake Igelsjon, south central Sweden, was studied by stable oxygen- and carbon-isotope analyses of different carbonate components. The deposit, which covers the time-span from ca 11,500 cal BP to the present, was laid down in a small, kettle-hole lake, the hydrological balance of which is presently dominated by groundwater flow. Isotopic records obtained on bulk ca

Myeloid cells play a central role in atherosclerosis. We investigated the associations between the plasma levels of growth factors and chemokines that regulate myeloid cell homeostasis and function and the risk of first-time acute coronary events in middle-aged persons. Methods and Results-We measured baseline plasma levels of macrophage colony-stimulating factor monocyte chemotactic protein 1; C-

Background: The epidemic of Alzheimer's disease (AD) represents a significant challenge for the health care and social service systems of many developed countries. AD affects both patients and family caregivers, on whom the main burden of care falls, putting them at higher risk of stress, anxiety, mortality and lower quality of life. Evidence remains controversial concerning the effectiveness of p

The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 is the update of similar evidence based position papers published in 2005 and 2007 and 2012. The core objective of the EPOS2020 guideline is to provide revised, up-to-date and clear evidence-based recommendations and integrated care pathways in ARS and CRS. EPOS2020 provides an update on the literature published and studies undert

Objectives: This study evaluated if selecting the left ventricular (LV) target segment by echocardiography-derived late mechanical activation, with access to multimodality imaging for scar and venous anatomy, could help to increase responder rates to cardiac resynchronization therapy (CRT). Background: LV lead placement is important for clinical outcome, but the optimal strategy for LV lead placem

In this concluding chapter, our aim is to outline the state-of-the-art within the deliberated topic in order to identify challenges for future research. Firstly, reminiscent of George Orwell’s aphorism “who controls the past controls the future”, we stress the importance of research into the origins of degraded and restituted towns in order to understand the socio-economic context that has shaped

Background: Sex workers have high incidences of HIV and other sexually transmitted diseases. Although, interventions targeting sex workers have shown to be effective, evidence on which strategies are most cost-effective is limited. This study aims to systematically review evidence on the cost-effectiveness of sexual health interventions for sex workers on a global level. It also evaluates the qual

Objective: The minor G allele of FOXO3A rs2802292 has been associated with longevity. We aimed to investigate whether a phenotype related to healthy metabolic aging could be identified in individuals carrying the longevity-associated FOXO3A rs2802292 G allele. Research Design and Methods: rs2802292 was genotyped in a phenotypically well-characterized population of young and elderly twins (n = 190)

As a social change, the sudden collapse of communism1 should well be remembered as one of the most formative events of the 20th century. As a political transformation, it caused an initial rush of euphoria within the 'victorious' West and a wave of hope followed by disillusionment for hundreds of millions in the newly ‘democratic’ sphere. As an economic transformation, its effects were even more t

Øresund EcoMobility contributes to knowledge creation for sustainable transport and green logistics, city transport, and energy systems with a specific focus on the conditions and needs of the Øresund region. In this book, long distance goods transport and strategies for green corridors through the Øresund and Europe are studied, multi-criteria models for analysis in transport and infrastructural