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Den bakomliggande orsaken till att islet amyloid polypeptide (IAPP) är cytotoxisk mot β-celler från bukspottkörteln tros vara prefibrillära oligomerer. Oligomererna skapas då IAPP ändrar konformation till amyloidfibriller. Förlusten av β-celler från cellklusterna har kopplats till typ II-diabetes. Ytterligare kunskap om hur man hindrar IAPP från att växla till den giftiga oligomerformen är oerhörtPrefibrillar oligomers are thought to be the “culprit” behind the cytotoxicity of islet amyloid polypeptide (IAPP) to pancreatic islet β-cells. The oligomers are generated in the process of IAPP’s conformational change into amyloid fibrils. The depletion of islet β-cells has been connected to type II diabetes. Knowledge of how to stop IAPP from switching into the cytotoxic oligomer form is of the

Examensarbetet utfördes i samarbete med Klarna i Giessen med syftet att utveckla en komponent i en del av en webbapplikation som hanterar autentisering. Komponenten skulle interagera med auktoriseringstjänsten försedd från Okta tillsammans med korrekt auktoriseringsflöde som en lösning för tillåten användning av webbapplikationen. Arbetet inleddes med en undersökning av webbapplikationen, bakomligThis thesis was written in collaboration with Klarna in Giessen with the purpose of developing a component to deal with authentication in a web application. The component is intended to interact with the authorization service from Okta with the correct type of authorization flow to allow or disallow access to the web application’s resources. At first, knowledge was gathered regarding the web appli

Catalytic partial oxidation of methane (CPOM) is an energy-efficient alternative to steam reforming, the currently prevailing method for energy production from natural gas. Hulteberg Chemistry & Engineering AB has developed a catalyst for the partial oxidation of methane into syngas, for use in solid oxide fuel cells. In its current form, the catalyst rapidly deactivates, causing increased mat

Det här examensarbetet utvecklar ett koncept för infästning av fenor på jetboards som inte intränger på befintliga patent. Det resulterande konceptet medför handlingsfrihet (FTO) och följaktligen tillåter produktion av fenor med originell design. FTO innebär möjligheten till att producera och sälja en produkt utan rättsligt ansvar gentemot ägare av patent. Examensarbetet presenterar och diskuterarThis master thesis generates a concept for the means of attaching fins onto jetboards without infringing on existing patents. The resulting concept establishes freedom to operate (FTO) and enables production of fins with original designs. FTO meaning the possibility of producing and selling a product without legal liability to any patent holders. The thesis further presents and discusses user need

This thesis examines the motives of IT employees to stay employed at their current job in an organisation or resign voluntarily and suggests possible factors for organisations to consider while designing retention strategies. The research was conducted as an inductive case study at an IT organisation headquartered in Sweden. A mixed method approach was adopted to gather empirical data through inte

2 juni 2026 12:15 till 13:15 | Seminarium AI and digital technologies affect democracy in many ways – through algorithms in social media, AI-generated information and disinformation, and the automated dissemination of political messages. In a series of seminars ahead of the Swedish election in 2026, AI Lund will present research that highlights how AI affects different aspects of democracy, but al

https://www.medarbetarwebben.lu.se/evenemang/ai-and-democracy-panel-discussion-lund-university-experts - 2026-07-18

New evidence and consensus has led to further revision of the McDonald Criteria for diagnosis of multiple sclerosis. The use of imaging for demonstration of dissemination of central nervous system lesions in space and time has been simplified, and in some circumstances dissemination in space and time can be established by a single scan. These revisions simplify the Criteria, preserve their diagnos

OBJECTIVES: This study clarified the exposure-response relationships for the organic acid anhydrides (OAA) hexahydrophthalic (HHPA) and methylhexahydrophthalic (MHHPA) anhydrides and the development of specific immunoglobulin (IG) E and G antibodies and work-related symptoms. METHODS: In an epoxy resin-using factory, air levels of OAA were determined by gas chromatography-mass spectrometry. Occupa

Emergency endovascular aneurysm repair (eEVAR) for ruptured abdominal aortic aneurysm (rAAA) must be carried out instantly. This requires firm logistics that include the ability to cross-clamp the aorta without delay. The present article focuses on the technique of balloon control of the aorta in eEVAR with aspects on indications as well as the organization of this type of vascular service. Transf

The Swedish reimbursement system operates a system where prices are set based on the expected value to the consumer. This value can be measured using willingness to pay (WTP).

This work focuses on the design of SC-LDPC codes for transmission over non-ergodic, block-fading channels. Our main contribution is an algorithm, allowing to start from a (J,K )-regular, uncoupled LDPC ensemble, from which one can recursively build up a protograph-based SC-LDPC ensemble having any target diversity order d. The diversity order is achieved assuming a low-complexity iterative decodin

This thesis presents a number of results and algorithms for the numerical solution of problems in geometric computer vision. In geometric computer vision one tries to extract geometric information about the world and the observer from a sequence of images. Estimation of scene structure and camera motion using only image data has been one of the central themes of research in photogrammetry, geodesy

Utilities, such as steam and cooling water, are often shared between several production areas at industrial sites, and the effects of disturbances in utilities could thus be hard to predict. In addition, production areas could be connected because of the product flow at the site. This paper introduces a simple modeling approach for modeling the relation between utility operation and production. Us

In this paper, we propose an alternative approach to array interpolation for the sectorized array processing of a uniform circular array. While other approaches do not fully consider the influence of out-of-sector signals on the in-sector response, our approach explicitly addresses this issue. By controlling the out-of-sector response, our interpolated array demonstrates a significantly improved a