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This thesis was dedicated to investigating the use of different parameter update schemes for Hidden Markov models with time-varying parameters, with an emphasis on developing alternatives to the quasi-Newton step. The focus was on applications to financial returns, using data from the S\&P-500 and the Nikkei index, and for comparison, a trial using synthetic data was also performed. Different
Death is a universal human experience, yet the ecological impact of the care and disposition of dead bodies is rarely considered, due in part to cultural taboos surrounding the physical reality of death and decomposition. If negative environmental consequences are to be limited, deathcare will need to adapt. Utilizing interviews with funeral directors from the United Kingdom, the United States and
Understanding the pH sensitivity of proteins and enzymes across intracellular compartments is crucial for fundamental research. Lizatović et al. [1] aimed to design a peptide incorporating a specific amino acid to form a hexamer structure and lacking it to form a pentamer structure. Unexpectedly, two distinct structures emerged based on pH. At pH 6, a hexamer structure formed, albeit with a surpri
The project was intended to explore the user needs around death and grief in todays Swedish society, with the assumptions that there is a mismatch between the needs and the existing offer of products and services in the area. An extensive research was made by qualitative user interviews, on-line research and readings. A number of opportunity areas for improvement was identified. The finally selec
In this commentary, we reflect on the program chair experience of ICIS 2015 to pass on some useful organizational memory for the IS community at large. We also reflect on volunteer effort required for a high-quality conference and the challenges of maintaining quality over a diverse and dispersed reviewing effort. We ask whether we can count on this volunteer effort in a changing higher education
BACKGROUND: Scintigraphy using technetium-99m labelled dimercaptosuccinic acid ([99mTc]Tc-DMSA), taken up in the proximal tubules, is the standard in functional imaging of the renal cortex. Recent guidelines recommend performing [99mTc]Tc-DMSA scintigraphy with single photon emission computed tomography (SPECT). Prostate-specific membrane antigen (PSMA) targeted positron emission tomography (PET)
Global urbanisation, increasing population, economic growth and development have caused increase in resource consumption, and consequently, a vast volume of waste and other negative environmental impacts. In order to reduce negative environmental impact, various approaches to resource management have been suggested and implemented in the system of production, consumption and waste management. One
To promote human flourishing throughout society, opportunities for arts participation must encompass all citizens. A primary means to promote this is arts education and activities for schoolchildren. Equal opportunities for participation are currently not enjoyed by students with disabilities. In a population-based and cross-sectional study carried out on a 2016 public-health survey including 27,3
Due to the public health threat that antibiotic resistance poses to humanity, there is increasing interest for understanding the mechanisms behind the development and transfer of antibiotic resistance genes (ARGs) in different environments. Soil is one of the largest and most diverse microbial habitats on earth and represents a vast terrestrial reservoir of organisms with tolerance to antibiotics.
Enhancement of anaerobic digestion of sewage sludge by enzyme addition was demonstrated in batch digestion tests. A pre-hydrolysation step with addition of enzymes at controlled temperature during 4 hours was shown to increase the methane yield significantly. Further tests with direct feeding of enzymes together with fresh sludge to the digester gave the same effect of a methane yield increase. Fo
Searches for resonant (ν) over tilde production in e(+)e(-) collisions under the assumption that R-parity is not conserved and that the dominant R-parity violating coupling is lambda(121) or lambda(131) used data recorded by DELPHI in 1997 to 2000 at centre-of-mass energies of 183 to 208 GeV. No deviation from the Standard Model was observed. Upper limits are given for the lambda(121) and lambda(1
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Antibodies are critical entities used for the protection of an individual organism against infection and disease. Through a complex series of events genes rearrange to encode repertoires of molecules, which are tested for their ability to identify foreign molecules. In this report, we discuss factors defined by the individual as well as by infectious organisms that shape the antibody repertoire. A
Recent progress shows that neurons suitable for transplantation can be generated from stem cells in culture, and that the adult brain produces new neurons from its own stem cells in response to injury. These findings raise hope for the development of stem cell therapies in human neurodegenerative disorders. Before clinical trials are initiated, we need to know much more about how to control stem c
The environmental footprint of IT products are significant and, in spite of manufacturing and product design improvements, growing consumption of electronics results in increasing absolute environmental impact. Computers have short technological lifespan and a lot of the in-build performance, although necessary, remains idling for most of the time. Today, most of computers used in non-residential
Background/Problematization: Iconic brands are the gold standard of branding and have established a central role in the consumers’ lives. Behind every iconic brand, we can find iconic products. Despite the importance of these products, iconic products are overlooked in academia. Few studies have explored the concept and there is no common definition or comprehensive framework. This is restrictive
