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Background: Globalization is a phenomenon which has been around since the mid- 19th century, influencing companies to either expand existing markets or entering new markets, to seek new profits. For companies with a global supply chain, the total supply chain cost is a vital factor. It is of high importance to reduce the costs in the supply chain, as lower costs will increase the profit. The case
Sweden has been struggling with bad access to healthcare. The National Healthcare Guarantee is not fulfilled, and Sweden has low productivity numbers. One suggested solution to deal with this issue is increased healthcare production control. Healthcare production control (HCPC) is the activity to actively trying to match healthcare needs with capacity. Public authorities are advocating increased h
Microsoft Word - Bacteria lab, retroviral production and vector surgery 2019 V2.docx Bacteria lab, Retroviral production and Vector surgery 2019 Report 1. Short description of the platform The main purpose of the platform is to produce high titer viral vectors for research purposes such as stereotactic delivery to the brain or ex vivo transduction with an emphasis on reprograming. The unit consist
Lipid bilayers are of interest in applications where a cell membrane mimicking environment is desired. The performance of the lipid bilayer is largely dependent on the physical and chemical properties of the component lipids. Lipid bilayers consisting of phytanoyl lipids have proven to be appropriate choices since they exhibit high mechanical and chemical stability. In addition, such bilayers have
Innovation strategies are crucial for corporate success and should be a top priority for packaging companies. However, to improve the innovativeness of packaging manufacturers, there is a need to increase the integration of product and packaging development and collaboration within the supply chain. New methods for innovative packaging development are needed. Packaging plays a valuable role in the
Tracking techniques are vital for the understanding of the biology and ecology of organisms. While such techniques have provided important information on the movement and migration of large animals, such as mammals and birds, scientific advances in understanding the individual behaviour and interactions of small (mm-scale) organisms have been hampered by constraints, such as the sizes of existing
Recent investigations-of the interaction between DNA and alkyltrimethyl ammonium bromides of various chain lengths are reviewed. Several techniques have been used such as phase map determinations, fluorescence microscopy, and electron microscopy. Dissociation of the DNA-surfactant complexes, by the addition of anionic surfactant, has received special attention. Precipitation maps for DNA-cationic
Popular Abstract in Swedish Det finns ett ökat intresse för behandling med talidomid. Därför var målsättningen med detta avhandlingsarbete att åstadkomma en mer ändamålsenlig användning. Några kemiska och farmakologiska aspekter med speciell inriktning på omsättningen av talidomid i människokroppen studerades. Historien om talidomid (Neurosedyn; varumärke i Sverige) är ett tragiskt kapitel i läkeThalidomide has a chiral center and the racemate of (+)-(R) and (-)-(S)-thalidomide was introduced as a hypnotic/sedative drug in 1957. In 1961 it was withdrawn due to teratogenicity and neuropathy. There is a growing interest in thalidomide treatment of immunomodulatory diseases. Given this renewed interest the aim of this thesis was to achieve a more rational use of thalidomide. Therefore some c
Popular Abstract in Swedish Hormonerna vasopressin och oxytocin frisätts från hypofysens baklob. Hypofysen är en körtel, som är belägen på undersidan av hjärnan och utsöndrar en rad olika hormoner vilka i sin tur påverkar och reglerar aktiviteten i en mängd andra organ. Vasopressin medverkar till regleringen av vatten- och saltbalansen i kroppen, men verkar också sammandragande på icke-viljestyrdVasopressin and oxytocin seem to have pivotal roles in the pathophysiology of primary dysmenorrhoea and preterm labour. Prostaglandins are also involved in the regulation of uterine activity with different receptors mediating both stimulation and relaxation. We explored different aspects of synthesis, release and receptor pharmacology of vasopressin and oxytocin. We also tested a vasopressin and o
Purpose: The frst main aim of this study was to illustrate the absorbed dose rate distribution from 177Lu in sections of xenografted prostate cancer (PCa) tumors using high resolution digital autoradiography (DAR) and compare it with hypothetical identical radioactivity distributions of 90Y or 7 MeV alpha-particles. Three dosimetry models based on either dose point kernels or Monte Carlo simulatio
Aims: Assessment following heart transplantation (HTx) is routinely performed using transthoracic echocardiography. Differences in long-term mortality following HTx related to donor-recipient matching have been reported, but effects of gender on cardiac size and function are not well studied. The aims of this study were to evaluate differences in echocardiographic characteristics of HTx recipients
In the early stages of the building design process, during the programming and the proposal stages, both user activities and the building are in focus for the designer. In spite of this, today’s CAD programs give no support for management of information about user activities in the building. This paper discusses the requirements on modelling us
Syftet med detta uppdrag har varit att utvärdera hur data på vinterförluster hos honungsbin i Sverige samlas in och analyseras, samt ge förslag på förbättringarav övervakning och analys.Denna rapport innehåller• En sammanställning av faktorer som kan påverka vinterförluster hos honungsbin under svenska förhållanden• En beskrivning av nuvarande sätt att rapportera och analysera vinterförluster i SvThis report evaluates current collection and use of data on winter loss in honey bees in Sweden and is a commission from the Swedish Professional BeekepersAssociation. It includes an overview of factors which may influence winter loss in honey bees in Sweden. In Sweden, data on winter loss is collected by twoinstances, the COLOSS survey and the Swedish Beekeepers Association (SBR). We identify sev
Pancreas transplantation is today a technically successful procedure and provides an alternative to insulin injections for the treatment of Type I diabetes mellitus. This thesis was undertaken while pancreas transplantation was developing and while several fundamental questions were being asked about both endocrine and exocrine drainage of the transplanted pancreas as well as how best to diagnose
This study introduces silicon substrates with a switchable magnetic contrast layer (MCL) for polarized neutron reflectometry (PNR) experiments at the solid–liquid interface to study soft-matter surface layers. During standard neutron reflectometry (NR) experiments on soft-matter samples, structural and compositional information is obtained by collecting experimental data with different isotopic co
Globins are usually associated with oxygen carriage in vertebrates. However, plants also contain similar heme-containing proteins, called phytoglobins (Pgbs). Unlike conventional hemoglobin, these proteins are often linked to nitric oxide metabolism, energy metabolism and redox maintenance under hypoxic and related abiotic and biotic stress conditions. Class I and II non-symbiotic Pgbs (nsPgbs) ha
