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Background Colorectal cancer (CRC) remains a major global health challenge with high morbidity and mortality despite advances in detection and treatment. Dietary polyphenols are secondary metabolites widely found in plant-derived foods and beverages, and have gained attention for their potential in CRC prevention and therapy due to their diverse biological activities. Methods This review synthesiz
The twin transition, which combines green and digital innovation in economic activities, is increasingly central to policy agendas and is also receiving growing attention in regional research. However, accurately mapping green, digital and twin (both green and digital) economic activities across regions remains challenging, particularly due to data constraints. In this study, we advance this resea
The potential effects of oral contraceptive (OC) and postmenopausal hormone (PMH) use are not well understood among BRCA1 or BRCA2 (BRCA1/2) deleterious mutation carriers with a history of breast cancer. We investigated the association between OC and PMH use and risk of contralateral breast cancer (CBC) in the WECARE (Women's Environment, Cancer, and Radiation Epidemiology) Study. The WECARE Study
In Sweden, the food and agricultural sector is highly concentrated, especially in the food refinement and retail sectors, with a few major actors holding significant market power. This concentration poses challenges for smaller agri-food companies in Skåne, Sweden. This thesis aims to in depth exploring the challenges smaller agri-food companies face today. The thesis employs a case study approach
The situation for the environment is in many ways dire. However, amidst all the negative environmental developments it is easy to neglect the successes that have actually happened. With the aim of better understanding what factors facilitated such a success this thesis analyses one such case, namely emissions of dioxins and chlorinated waste from the pulp and paper industry in Sweden. Dioxins were
How does democracy affect income inequality? Most would expect democracy to reduce income inequality. There is a general consensus that indeed democratizations in Europe during the nineteenth and early twentieth century did decrease income inequality. More recent democratizations, those countries that democratized during the 1970s-1990s, however, do not seem to have had the same effect. The body o
The COVID-19 pandemic revealed the fragility of the global food system and its existing inadequacies in achieving food security, providing jobs, and ensuring environmental sustainability on various regimes around the world. Through a qualitative thematic-textual analysis, this thesis uses a case study of New York City to identify themes of actor expectations, either explicit or implicit, on how to
Purpose: The purpose of this paper is to investigate how manufacturing firms use cost drivers and if any factors affect manufacturing firms’ cost driver approach. Theoretical Perspective: The thesis theoretical perspective concentrates on explaining the concept of cost drivers, reviewing existing empirical findings and identification of factors which could affect manufacturing company´s approach
In 2008 the National Library of Sweden made a decision to change the Swedish classification system SAB to the internationally used Dewey Decimal Classification (DDC), a decision that was supported by the Swedish Library Association that recommended all Swedish libraries to make the change. The main reasons and arguments were internationalisation and rationalisation; less time should be laid on cla
The aim of this paper is to analyze Peter Linde’s sculpture the Statue of Zlatan as a work of art in a public space and what kind of meaning is produced through its different kinds of expressions. Based on theories concerning public art, ancient Greek and Roman sculptural traditions and iconoclasm, this paper explains how the sculpture is drawing on older sculptural traditions to narrate the obser
The genetic contributions to early onset heart failure (HF) are incompletely understood. Genetic testing in advanced HF patients undergoing heart transplantation (HTx) may yield clinical benefits, but data is limited. We performed deep-coverage whole genome sequencing (WGS) in 102 Swedish HTx recipients. Gene lists were compiled through a systematic literature review. Variants were prioritized for
Introduction Emerging research indicates that integrated treatment of co-occurring post-traumatic stress disorder (PTSD) and substance use disorder can be effective among adolescents and young people. However, various barriers exist to young people accessing evidence-based treatments. Telehealth offers an opportunity to address these barriers and provide a scalable and accessible alternative to in
BackgroundSymptom severity cutoffs for body dysmorphic disorder (BDD) are lacking, hindering communication between professionals and with the patient community.MethodWe pooled data from 11 clinical trials or high-quality cohort studies from specialist clinics, totaling 804 individuals with BDD (80 % girls/women, 67 % adults). All participants had baseline scores on the adult or adolescent versions
Jaboticaba (Plinia jaboticaba) is an underutilized Brazilian berry and a source of dietary fiber, cyanidin-3-O-glucoside, and ellagic acid derivatives. Non-clinical studies have shown the potential of jaboticaba to alleviate insulin resistance, low-grade inflammation, and obesity-related cognitive decline, although clinical evidence remains limited. A clinical study was conducted to investigate wh
OBJECTIVE AND DESIGN: The objective was to determine the association between serum IgE levels and the infiltration order of T lymphocytes and macrophages in pancreatic islets in relation to the loss of insulin and glucagon cells in presymptomatic congenic BB Gimap5-DP (Diabetes Prone) rats.MATERIAL: Congenic prediabetes BB Gimap5-DP and control Gimap5-DR (Diabetes Resistant) rats were followed eve
To meet national and international emission targets, the Swedish building sector needs to drastically reduce its carbon dioxide emissions, and to do so, a change in building techniques and materials is needed. Bio-based materials contribute to less emissions than conventional materials, like steel and concrete, but remain rather unknown to modern building sciences. This study aimed to increase kno To meet national and international emission targets, the Swedish building sector needs to drastically reduce its carbon dioxide emissions, and to do so, a change in building techniques and materials is needed. Bio-based materials contribute to less emissions than conventional materials, like steel and concrete, but remain rather unknown to modern building sciences. This study aimed to increase kn
Hard alumina-based coatings can be applied to cast iron brake discs using a plasma electrolytic aluminating (PEA) process to enhance wear and corrosion resistance and reduce brake particle emissions. This work was first to study the influence of friction wear on corrosion property and then investigate the influence of corrosion on brake particle emissions from cast iron discs through comparison of
BACKGROUND: Gastrectomy including D2 lymphadenectomy is regarded as the standard curative treatment for advanced gastric cancer in Asia. This procedure has also been adopted gradually in the West, despite lack of support from RCTs. This study sought to investigate any advantage for long-term survival following D2 lymphadenectomy in routine gastric cancer surgery in a Western nationwide population-
Land-use change affects both the quality and quantity of soil organic carbon (SOC) and leads to changes in ecosystem functions such as productivity and environmental regulation. Future changes in SOC are, however, highly uncertain owing to its heterogeneity and complexity. In this study, we analyzed the outputs of simulations of SOC stock by Earth system models (ESMs), most of which are participan
