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Nyttovärdering av IT-investeringar

I dagens samhälle görs IT investeringar i alla tänkbara verksamheter. Om investeringen lyckas eller inte beror bland annat på förståelsen av vilka delar av verksamheten som kommer att påverkas samt hur de kommer att påverkas. Uppsatsen behandlar hur nyttovärdering av IT-investeringar görs i verkligheten i jämförelse med vad som nämns i litteraturen. Syftet med uppsatsen är att få grepp om olika as

Myocardial infarction - Risk stratification and evaluation of therapies

Background. Myocardial infarction (MI) remains the leading cause of death worldwide, despite several advances in acute coronary care during the last decades. This thesis assessed different risk stratification tools and evaluated interventional and pharmacological treatment strategies in high-risk patients with MI. Methods. This work comprises four studies. The first and the fourth study extracted

Activity evoked by A- and C-afferent fibers in rat dorsal horn neurons and its relation to a flexion reflex

The responses of 56 neurons recorded in the lumbosacral spinal cord of halothane-anesthetized rats were studied following the application of mechanical stimuli to the skin on the lateral aspect of the paw or electrical stimulation of the sural nerve. Only neurons driven by A- and C-fiber stimulation were considered. The evoked activity in a nerve supplying flexor muscles, the common peroneal nerve

Cumulative live birth rate after IVF : Trend over time and the impact of blastocyst culture and vitrification

STUDY QUESTION: Has cumulative live birth rate (CLBR) improved over time and which factors are associated with such an improvement? SUMMARY ANSWER: During an 11-year period, 2007-2017, CLBR per oocyte aspiration increased significantly, from 27.0% to 36.3%, in parallel with an increase in blastocyst transfer and cryopreservation by vitrification. WHAT IS KNOWN ALREADY: While it has been shown that

Small-scale rainwater cistern system for rainwater collection in north-western China

Despite the overall rapid economical development during the last decade in China, a number of regions in remote areas are still striving to alleviate poverty. These regions are commonly characterized by low level of industrialization, poorly developed agriculture, which almost entirely relies on climate situations. Water has often been a bottle-neck in the development of the agricultural, industri

Effect of IL-1beta secretion on lymphoid tissue and on antitumor immune responses

Popular Abstract in Swedish Kroppens immunförsvar är vårt skydd mot främmande "inkräktare", såsom virus, bakterier och parasiter. Om dessa mikroorganismer tar sig förbi de fysiska barriärerna, dvs. hud, slemhinnor saliv mm, aktiveras immunsystemet. Immun-försvaret kan delas in i det nedärvda eller naturliga försvaret samt det för-värvade försvaret. Det naturliga försvaret aktiveras först och huvudInterleukin (IL)-1beta is one of the most pleiotropic and potent cytokines, produced predominantly by activated monocytes and macrophages. IL-1 plays an important role in normal immunoregulatory processes but also in pathophysiological inflammatory responses. In the present study, we developed a model for active IL-1beta secretion. A retroviral vector containing a cDNA construct encoding the matur