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We propose a simple architecture for implementing supervised neural network models optically with photorefractive technology. The architecture is very versatile: a wide range of supervised learning algorithms can be implemented including mean-field-theory, backpropagation, and Kanerva-style networks. Our architecture is based on a single crystal with spatial multiplexing rather than the more commo
T-cell development provides an excellent model system for studying lineage commitment from a multipotent progenitor. The intrathymic development process has been thoroughly studied. The molecular circuitry controlling it has been dissected and the necessary steps like programmed shut off of progenitor genes and T-cell genes upregulation have been revealed. However, the exact timing between decisio
Quantum annealing has shown promise for finding solutions to difficult optimization problems, including protein folding. Recently, we used the D-Wave Advantage quantum annealer to explore the folding problem in a coarse-grained lattice model, the HP model, in which amino acids are classified into two broad groups: hydrophobic (H) and polar (P). Using a set of 22 HP sequences with up to 64 amino ac
While Ellis, Reid, and Kramer’s life history framework is convincing in explaining individual variation in life history strategies, it has certain limitations, which we discuss – drawing notably on the economic theory of fertility choice. In particular, we suggest that ambient cues to extrinsic mortality alone are not sufficient to trigger sustained net fertility decline.
Event cameras and LiDARs provide complementary yet distinct data: respectively, asynchronous detections of changes in lighting versus sparse but accurate depth information at a fixed rate. To this day, few works have explored the combination of these two modalities. In this article, we propose a novel neural-network-based method for fusing event and LiDAR data in order to estimate dense depth maps
Background: 112 patients who received small and medium sized St.Jude Regent heart valves (19-25 mm) at 7 Scandinavian centers were studied between January 2003 and February 2005 to obtain non-invasive data regarding the hemodynamic performance at rest and during Dobutamine stress echocardiography (DSE) testing one year after surgery. Material and methods: 46 woman and 66 men, aged 61.8 +/- 9.7 (18
The centenarian Tröger’s base (TB) was envisaged as scaffold for the construction of tubular-shaped cleft molecules due to its the remarkable structural properties. This endeavor started with the synthesis of the three possible diastereomers of a linear symmetrically fused tris-TB analogue, the anti-anti, the syn-syn, and the syn-anti. All three diastereomers showed unprecedented stability to acid
Popular Abstract in Swedish Hållbara matvanor - från jord till bord I Sverige äter vi i genomsnitt 800 kg mat per person och år. Vad och hur mycket vi väljer att stoppar i oss har stor betydelse både för planetens och vårt eget välmående. Den här avhandlingen handlar om hur våra val av livsmedel i den dagliga kosten påverkar miljön och hälsan. Vilken typ av livsmedel vi väljer att äta och dessa Food production and consumption are key drivers of environmental pressures and are essential factors in the promotion and maintenance of health. Production of food occupies more than one third of global land areas and is estimated to be responsible for some 30% of global greenhouse gas emissions. At the same time, we live in a world where nearly one billion people go hungry and even more people su
Background: Adipic acid (AA) is one of the most important industrial chemicals used mainly for the production of Nylon 6,6 but also for making polyurethanes, plasticizers, and unsaturated polyester resins, and more recently as a component in the biodegradable polyester poly(butylene adipate terephthalate) (PBAT). The main route for AA production utilizes benzene as feedstock and generates copious
In the framework of the ESO Large Programme ``First Stars'', veryhigh-quality spectra of some 70 very metal-poor dwarfs and giants wereobtained with the ESO VLT and UVES spectrograph. These stars are likelyto have descended from the first generation(s) of stars formed after theBig Bang, and their detailed composition provides constraints on issuessuch as the nature of the first supernovae, the eff
BACKGROUND: Permanent pacemaker implantation (PPM) early after cardiac transplantation has been shown not to predict a worse outcome. However, the requirement for pacing late after transplantation and its prognostic implications are not fully known. We describe the clinical indications, risk factors and long-term outcome in patients who required pacing early and late after transplantation.METHODS:
Nature-based tourism in the fragile Arctic environments is emerging as a major environmental concern, mainly due to extreme seasonality in these locations, the lack of suitable infrastructures and planning, and its interference with fragile ecosystems. In Iceland tourism has increased exponentially during the past decades, causing more environmental impacts on the country's natural recourses. Hiki
Hong and Kao (2004) proposed a class of general applicable wavelet-based tests for serial correlation of unknown form in the residuals from a panel regression model. The tests can be applied to both static and dynamic panel models. Their test, however, is computationally difficult to implement, and simulation studies show that the test has poor small-sample properties. In this paper, we extend Gen
Objective: Needle acupuncture in small children has gained some acceptance in Western medicine. It is controversial, as infants and toddlers are unable to consent to treatment. We aimed to assess its efficacy for treating infantile colic. Design: A systematic review and a blinding-test validation based on individual patient data from randomised controlled trials. Primary end-points were crying tim
A large portion of atmospheric aerosol particles consists of secondary material produced by oxidation reactions. The relative importance of secondary organic aerosol (SOA) can increase with improved emission regulations. A relatively simple way to study potential particle formation in the atmosphere is by using oxidation flow reactors (OFRs) which simulate atmospheric ageing. Here we report on the
The overall objective of this thesis is to understand the role of diversification at household level, its patterns, determinants and effects on rural smallholder farmers in SSA, as well as its implications for the process of structural transformation in SSA. In the thesis, I use a mixed methodology and combine different types of data on rural smallholders in SSA to answer the objectives a review o
BACKGROUND: Previous studies have shown that approximately 20% of hospital readmissions can be medication-related and 70% of these readmissions are possibly preventable. This retrospective medical records study aimed to find risk factors associated with medication-related readmissions to hospital within 30 days of discharge in older adults (≥65 years).METHODS: 30-day readmissions (n = 360) were as
