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Disturbances in intestinal metabolism and perfusion during SIRS can be direct effects of toxic substances, and/or effects secondary to hypovolemia. An attempt to evaluate the significance of hypovolemia for intestinal disturbances during SIRS was made in the present study on feline by evaluating the degree to which the intestinal alterations following endotoxin infusion were restored by a clinical

A new EU directive on used vehicles has recently been introduced. It demands that for every scrapped car, at least 85% by weight must be recycled by the year 2006 and 95% by 2015. Today this level is about 80%. The growing car disassembly industry was chosen as the study object of this thesis. Due to the increased demands on recycling, the disassembly industry is expected to undergo comprehensive

BACKGROUND: There is little consensus on a standard approach to analysing bone scan images. The Bone Scan Index (BSI) is predictive of survival in patients with progressive prostate cancer (PCa), but the popularity of this metric is hampered by the tedium of the manual calculation. OBJECTIVE: Develop a fully automated method of quantifying the BSI and determining the clinical value of automated

Reducing eutrophication in our surface waters caused by nutrient overload is of importance in order to ensure an environment in ecological balance for future generations. Municipal wastewater treatment plants are the main point source of nutrients emissions. Effluent water can be treated by introducing a final advanced treatment step to existing wastewater treatment plants. The present thesis conc

Background & Aims Cholera toxin can act as a modulator of the immune response with anti-inflammatory effects; it reduces development of colon polyps in mouse models of colorectal cancer (CRC). We performed a population-based study to determine whether, in patients with a diagnosis of CRC, subsequent administration of the cholera vaccine (killed Vibrio cholerae O1 whole cells and recombinant ch

Reduction of the anticancer trans platinum(IV) prodrug JM335 by thiols in a moderately alkaline aqueous perchlorate medium is quite rapid and yields trans-[Pt(OH)2(c-C6H11NH2)(NH3)] as the reaction product. The mechanism of reduction involves reductive attack by thiol or thiolate on one of the mutually trans chloride ligands, leading to the formation of a chloride-bridged activated complex.The red

Familial clustering of pleural mesothelioma was reported previously, but none of the reports quantified the familial risk of mesothelioma or the association with other cancers. The contributions of shared environmental or genetic factors to the aggregation of mesothelioma were unknown. We used a number of Swedish registers, including the Swedish Multigeneration Register and the Swedish Cancer Regi

Background: Personal history of type 2 diabetes mellitus (T2DM) is associated with a lower incidence of prostate cancer, but the underlying mechanisms are largely unknown. We hypothesized that genetic factors that are involved in the development of T2DM might protect against prostate cancer. Methods: We used a few Swedish registers, including the Swedish Multigeneration Register and the Cancer Reg

The risk of solid and hematological malignancy in patients with Turner syndrome, characterized by X chromosome monosomy in women, and Klinefelter syndrome, characterized with two and more X chromosomes in men, is not well established, but such evidence may have etiological implications on cancer development. We identified a total of 1,409 women with Turner syndrome and 1,085 men with Klinefelter s

Increased risks of certain cancers have been observed in patients with hepatitis C virus (HCV) infection. However, data on other cancer sites/types are lacking. We analyzed systematically the risk of developing 35 common cancers in patients with HCV infection using a nationwide Swedish database. Patients with HCV infection were identified from the Swedish Hospital Inpatient and Outpatient Register

A way to reduce net CO2 emission and circumvent the high particle emissions from compression ignition (CI) engines, while retaining high efficiency, is by utilizing lighter alcohols in the partially premixed combustion (PPC) process. Methanol and ethanol have a very short carbon chain, and form less soot/particulate matter (PM) during combustion compared to diesel fuel. This study analyzes and com

In order to describe a novel approach for the clinical study of metastases, we provide here age-specific incidence and survival data for cancer of unknown primary (CUP). Metastases in various organs are found at CUP diagnosis, which have implications for prognosis, and we hypothesize similar prognostic implications for metastases found at diagnosis of primary cancers. We identified 33,224 CUP pati

H.G. Wells’ novella The Time Machine (1895) tells the story of The Time Traveller who travels to the year 802,701. There, he encounters two evolutionary progressions of humanity. One, Morlocks, have been read as representations of Victorian workers and poor, and the other, the Elois, as representations of the aristocracy. The Time Traveller represents the middle class. The novella is often seen as

Binära föreningar beståendes av sällsynta jordartsmetallerna och rutenium uppvisar intressanta egenskaper såsom superledande förmåga och intressanta magnetiska egenskaper. För att förstå varför vissa föreningar uppvisar sådana egenskaper är det essentiellt att studera föreningarnas kristallstruktur. I denna rapport undersöks föreningar, i 35-38 at. % Ru regionen, beståendes av praseodym, neodymiumBinary alloys comprising of the rare earth metals along with ruthenium, RE-Ru, have been noted to display superconductivity at low temperatures. Furthermore the alloys display interesting magnetic properties such as anomalies in magnetization measurements below the magnetic ordering temperature. In order to understand how some compounds obtain these intrinsic properties it is vital to investigate

This master thesis project was completed in partnership with Lantmännen, known for producing Gluten Free (GF) PromOat®—a concentrated oat β glucan powder. The main aim of the thesis was to explore the properties of emulsions containing GF PromOat® oat β-glucan. It specifically focuses on the critical overlap concentration, viscosity, and stability before and after high-pressure homogenization

This study explores the different psychological processes and psychological capital resources that help entrepreneurs sustain motivation to re-enter entrepreneurship after discontinuing a previous venture. While existing literature has focused intensely on the financial and social costs of business failure, minimal yet growing scholarly attention has focused on the psychological costs of failure a

The aim of this study was to achieve realistic levels of two different types of aerosols commonly abundant in indoor environments in an experimental chamber intended for human exposure studies and aerosol characterization. The aerosols chosen were particles from candle lights (in particle number dominated by inorganic water soluble particles) and from ozone-terpene reactions (organic particles). T