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A polymorphism consisting of a deletion near the 5' splice site of exon 18 on the alpha2-macroglobulin (A2M) gene (A2M-2) has been suggested to be associated with Alzheimer's disease (AD) in family-based studies. We studied the A2M-2 allele together with the ApoE alleles in a large series on patients with AD (n = 449) and age-matched controls (n = 349). Neuropathologically confirmed diagnoses were
Närståendes närvaro hos patienter som är kritiskt sjuka underlättar enligt studier patienternas vistelse på intensivvårdsavdelningen. För att stödja och tillhandahålla information till de närstående bör personal på intensivvårdsavdelningar vara medvetna om närståendes uppfattningar. I Kanada har ett enkätformulär FS-ICU utvecklats för att undersöka närståendes tillfredsställelse med vården och med
A sample of 107 asset sales completed globally from October 2006 to January 2019 has been investigated to find the average discount at which the assets of distressed energy companies are liquidated. In the next step, the difference in difference approach has been used to explore the oil price crash in the fourth quarter of 2014 so as to find the difference in the average discount on the assets of
s_constr_meth.dvi Structural Mechanics PER-ERIK AUSTRELL KONSTRUKTIONSBERÄKNINGAR FÖR GUMMIKOMPONENTER Report TV SM -7131 PER -ER IK A U STR ELL K O N S T R U K T IO N S B E R Ä K N IN G A R FÖ R G U M M IK O M P O N E N T E R Detta är en tom sida! Copyright © 2000 by Structural Mechanics, LTH, Sweden. Printed by KFS i Lund AB, Lund, Sweden, June 2001. For information, address: Division of Structu
https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm7000/web7131.pdf - 2026-07-17
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Background: Motion sickness (MS) is a common complaint during most modes of travel. Several medications can be used to treat MS but are often accompanied by side-effects. Objective: To assess whether performing the Valsalva manoeuvre can influence the subjective feeling of MS in healthy individuals. Methods: We included 16 healthy participants (4 female) that underwent two sessions of MS induction
Peatlands store a substantial amount of carbon in the terrestrial ecosystem. They are both long-term sinks of organic carbon and a major natural source of atmospheric methane. The accumulation of carbon is a result of net primary production surpassing decomposition rates over millennia, whereas methane production is intricately linked to the anaerobic decomposition of carbon mass. Warming-induced
This paper deals with the question of the ne bis in idem rule, known in the Common Law Countries as 'double jeopardy'. The rule's purpose is to protect a person from being prosecuted or sentenced for an offence a second time, for which he or she had already been tried, whether convicted or acquitted. The paper comprises two parts: the first is related to the question of the ne bis in i
In this overview the technique of accelerator mass spectrometry (AMS) and its use are described. AMS is a highly sensitive method of counting atoms. It is used to detect very low concentrations of natural isotopic abundances (typically in the range between 10(-12) and 10(-16)) of both radionuclides and stable nuclides. The main advantages of AMS compared to conventional radiometric methods are the
Objective. Our aim was to study the risk of a first ischaemic stroke (IS) in patients with atrial fibrillation (AF) treated in primary healthcare. Design. The study population included all adults (n = 11,517), 45 years and older diagnosed with AF, from 75 primary care centres in Sweden between 2001 and 2007. IS was defined as a hospital care event of stroke between 2001 and 2010. Association betwe
Homeodomain-interacting protein kinase 2 (Hipk2) has previously been implicated in the control of several transcription factors involved in embryonic development, apoptosis, cell proliferation, and tumor development, but very little is understood about the exact mechanisms through which Hipk2 influences these processes. Analysis of gene expression in normal tissues from genetically heterogeneous m
The prognostic impact of t(12;21)(p13;q22) [ETV6/RUNX1 fusion] in paediatric acute lymphoblastic leukaemia (ALL) has been extensively debated, particularly with regard to the frequency of late relapses and appropriate treatment regimens. We have retrospectively collected 679 ALLs with known ETV6/RUNX1 status, as ascertained by fluorescence in situ hybridization or reverse-transcription polymerase
The strong correlation between smoking and exposure to oncogenic human papillomaviruses (HPVs) has made it difficult to verify the independent role of smoking in cervical carcinogenesis. Thus, the authors evaluated this role. Five large Nordic serum banks containing samples from more than 1,000,000 subjects were linked with nationwide cancer registries (1973-2003). Serum samples were retrieved fro
Bone mineral density (BMD) in the lumbar spine and femoral neck, the incidence of osteoporosis, and survival up to 10 years after heart transplantation (HT) were investigated in 169 patients who underwent HT at Skåne University Hospital in Lund, Sweden, 1988-2016. Within the first year post-transplantation, mean (SD) BMD decreased by 3.9% (10.1) (P < 0.001) and 9.0% (10.5) (P < 0.001) in the lumba
Population-based data on the incidence and surgical treatment of patients with colorectal cancer (CRC) and synchronous liver and lung metastases are lacking as are real-life data on the frequency of metastasectomy for both sites and outcomes in this setting. This is a nationwide population-based study of all patients having liver and lung metastases diagnosed within 6 months of CRC between 2008 an
Background: People with late effects of polio (LEoP) may need rehabilitation to manage everyday life but knowledge of the benefits of interdisciplinary rehabilitation is limited.Objective: To evaluate changes in performance and satisfaction with performance of activities among people with LEoP following interdisciplinary rehabilitation.Methods: A pre-post retrospective study based on data on 102 p
