Filetype
The natural history of carotid artery disease was studied in a retrospective study of 609 angiograms performed during 1969-1979 on patients who had subsequently not been operated on. The indication for angiography differed, but was aimed at clarifying suspected cerebrovascular events. 578 patients could be followed-up after a median time of 10.4 years (0-22). The median survival time after angiogr
Objectives. To compare the incidence of haemorrhagic stroke (HS), and the risk of fatal outcome after HS in patients with oral anticoagulation (OA) treatment and in the general population. Design. Five-year cohort study. Setting. The Anticoagulation Clinic, Malmo University Hospital, Lund, Sweden. Subjects. A total of 4434 patients treated with OA (6693 treatment years) from 1 Oct 1993 to 30 Sept
A method for determination of N-methylsuccinimide (MSI) and 2-hydroxy-N-methylsuccinimide (2-HMSI) in human urine and of MSI in human plasma was developed. MSI and 2-HMSI are metabolites of the widely used organic solvent N-methyl-2-pyrrolidone (NMP). MSI and 2-HMSI were purified from urine and plasma by C8 solid-phase extraction and analysed by gas chromatography-mass spectrometry in the negative
Abstract Background and ObjectiveFluorescence techniques can provide powerful noninvasive means for medical diagnosis, based on the detection of either endogenous or exogenous fluorophores. The fluorescence of δ-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) has already shown promise for the diagnosis of tumors. The aim of the study was to investigate the localization of skin tumors a
Objective: To clarify the relationship between symptoms, clinical signs and physiological abnormalities that were motivating the initiation of home mechanical ventilation in patients suffering from neuromuscular diseases. Methods: From The Swedish Home Mechanical Ventilation Register we identified 352 patients with neuromuscular diseases and we looked at circumstances ( acute vs elective) and clin
Lipoprotein(a) [Lp(a)], a strong independent cardiovascular risk factor, consists of the unique apolipoprotein(a) [apo(a)] covalently linked to a low-density lipoprotein particle. Apo(a) contains a widely differing number of the plasminogen-like kringle IV, a size polymorphism that is codominantly inherited. In addition to powerful genetic control, renal failure is known to influence the plasma Lp
In this thesis we look at data where sedated patients have been pinpricked with a needle during an Auditory Brainstem Response recording. By looking at this data set with different statistical methods some butterfly pattern emerged and peaks appeared in the spectrum around the time where the needle pinpricking should have occurred. With this results a model was developed and evaluated. Future inve
This master thesis is commissioned by the company Haldex Brake Products AB based in Landskrona. The company is acting on the road vehicle market. Amongst other products the company produces disc brakes for the heavy road vehicle industry. Disc brakes developed by Haldex, based on the sliding caliper principle, are during certain circumstances experiencing problems with malfunction of the brake due
In Sweden, hypertension, is one of the most common reasons to attend primary care thus a Swedish public health problem of epic proportions. There is a general consensus about that effective antihypertensive treatment reduces the risk of developing cardiovascular diseases and premature death. Non-pharmacological treatment is advocated to be the basis of treatment. The caregiver is responsible for s
A proteoglycan is a protein with at least one glycosidic chain or glycosaminoglycan (GAG) covalently bound to it. Since a common linker between the core protein and the GAG chain has a xylose present, the biosynthesis of GAGs can be primed using xylosides containing hydrophobic aglycons providing that these xylosides are capable of penetrating the cell membrane. 2-naphthyl β-D-xylopyranoside prim
Purpose: Supply chain efficiency (economic and ecological) is affected by packaging design. The purpose of this research is to investigate how integrated approaches aiming for ecoefficient supply chains are used in packaging development processes and how a set of preselected factors influences the adaption of more or less integrated approaches at companies. Design/methodology/approach: The researc
Biomechanical models which require information on, e.g., joint torque and muscle force are useful in the estimation of when and how mechanical overload of the musculoskeletal system may lead to disorders. The aim was to study the reliability and validity of magnetic resonance imaging (MRI) to quantify muscle sizes and moment arms by MRI and to test selected anthropometric measures as predictors of
Hormone-sensitive lipase (HSL), a key enzyme in fatty acid mobilization in adipocytes, has been demonstrated also in skeletal muscle. To gain further insight into the role and importance of HSL in skeletal muscle, a transcriptome analysis of soleus muscle of HSL-null mice was performed. A total of 161 transcripts were found to be differentially expressed. Increased mRNA levels of fructose-1,6-bisp
OBJECTIVE: To determine and analyse the incidence of childhood injuries in Reykjavik 1974-1991. DESIGN: Descriptive, retrospective study. SETTING: Reykjavik City district with a mean number of 88700 inhabitants, of which 23.4% were children under 15 years of age. SUBJECTS: All children 0-14 years old who came to the emergency department at Reykjavik City Hospital because of an injury. MAIN OUTCOME
In patients with intermediate or high grade non-Hodgkin lymphoma (NHL), third generation chemotherapy regimens have been introduced to improve survival in comparison with the standard CHOP regimen. However, most studies have found no difference between these two treatments. We conducted a meta-analysis to assess the effectiveness of third generation regimens as compared with CHOP. Our study includ
Objectives Exposure to diisocyanates is a well known occupational hazard. The objective of this study was to determine the possibility of an association between low exposure to toluene diisocyanate (TDI) (airborne isocyanates and biomarkers of isocyanates in plasma and urine) and symptoms of the eyes and upper and lower airways. Methods Altogether 136 workers occupationally exposed to TDI and 118
The freeze-drying tolerance of Pseudomonas chlororaphis, an antifungal bacterium used as biocontrol agent was investigated. P. chlororaphis is freeze-drying sensitive and the viability drops more than 3 log units in the absence of protective freeze-drying medium. Of the freeze-drying media tested, lactose, sucrose, trehalose, glutamate, sucrose with glutamate, skimmed milk, and skimmed milk with t
Cardiovascular nursing (CVN) is rapidly developing and has accumulated a large amount of evidence to support interventions aimed at reducing suffering and hastening recovery. However, knowledge of the extent and content of CVN training in Sweden is lacking. The aim of this study was therefore to identify and describe CVN in the Swedish RN education as well as in higher education, with reference to
