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HLA-DR genes are associated with the progression from stage 1 and stage 2 to onset of stage 3 type 1 diabetes (T1D), after accounting HLA-DQ genes with which they are in high linkage-disequilibrium. Based on an integrated cohort of participants from two completed clinical trials, this investigation finds that sharing a haplotype with the DRB1*03:01 (DR3) allele, DRB3*01:01:02 and *02:02:01 have re
The growing need for human-machine interfaces (HMIs) underscores the importance of sensory feedback, with electrical stimulation offering efficient interaction in various applications. While its sensory effects are extensively studied, investigations into the reaction time (RT) following transcutaneous electrical stimulation (TES) remain limited. This study aimed to evaluate how stimulation parame
The ability to predict the absorption of exenatide (Ex), a GLP-1 analogue, after oral dosing to rats in self-nanoemulsifying drug delivery systems (SNEDDS), using in vitro methods, was assessed. Ex was complexed with soybean phosphatidylcholine (SPC) prior to loading into SNEDDS. A design of experiments (DoE) approach was employed to develop SNEDDS incorporating medium-chain triglycerides (MCT), m
Risk factors for developing bloodstream infections (BSIs) caused by Aerococcus bacteria remain insufficiently examined. In this nationwide case–control study in Sweden, 19 of 23 clinical microbiological laboratories identified patients who had aerococcal BSIs during 2012–2016. We compared each of those index patients with 4 controls matched for age, sex, and county of residence. Overall, 588 episo
Introduction. There is no water-tight division between different categories of human rights. In particular, it is important to note that although the project of transforming the 1948 Universal Declaration of Human Rights into treaty form culminated in separate Covenants including, on the one hand, civil and political Rights and, on the other hand, economic, social and cultural Rights, it did not r
General issues Basic features The International Covenant on Civil and Political Rights (ICCPR) was adopted by the United Nations General Assembly in 1966, and, after the required number of ratifications, it entered into force on 23 March 1976. To a large extent the Covenant, together with the simultaneously adopted International Covenant on Economic, Social and Cultural Rights, codifies in the for
Musculoskeletal disorders are a significant public health burden concern, projected to increase in the coming decades, and will substantially contribute to the rising prevalence of functional impairment, frailty and disability in a growing global population. Since persons with musculoskeletal disorders tend to have immune dysfunction, inflammation or be taking immunosuppressive medication, prevent
Proenkephalin (PENK) is assumed to be freely filtered by the glomerulus, thus potentially useful for estimating glomerular filtration rate (eGFR). Recently developed eGFR-equation based on PENK and creatinine has not been validated against existing cystatin C-based equations. This study aimed to test the hypothesis of free filtration of PENK. Also, the PENK-creatinine based eGFR-equation was valid
We have calculated redox potentials of 12 blue copper protein sites comparing 64 computational methods, systematically varying the quantum mechanics (QM) system size, dielectric constants, density functional, and basis sets. All methods were based on structures optimized with combined QM and molecular mechanics (QM/MM) approaches. The redox potentials were evaluated using 10 quality metrics. The b
Over the course of almost four decades the world has been left vulnerable by the HIV epidemic. Displaying the biggest public health challenge currently, many scholars aim to further the understanding of the mechanisms of the spread of HIV. This study aims to contribute to the existing body of literature through adding a spatial aspect to research performed on HIV key drivers in Uganda. Furthermore
The study aims to understand the influence of environmental and lifestyle factors and more specifically the role of tobacco smoke–infused water (tuibur) on Helicobacter pylori infection. It was a cross-sectional study to measure the epidemiological risk factors associated with H. pylori infection among the tribal population in Northeast India. Endoscopic samples were collected from the antrum regi
Inbjudan I n s t i t u t i o n e n f ö r m i l j ö v e t e n s k a p l i g u t b i l d n i n g 2015-08-14 PRELIMINÄRT SCHEMA PRELIMINÄRT Schema för MVET10 miljöskydd, 15 hp ht 15 Kurstid: 31 augusti – 1 november 2015 Kursansvarig: Högni Hansson 0721-55 56 48, hogni.hansson@cec.lu.se Introduktion: måndagen den 31 augusti 2015, Ekologihuset, Maskrosen, kl. 10.15-11.00. Lärare: Högni Hansson hogni.ha
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schema_mvet10_ht15_v2-2.pdf - 2026-07-17
Starting from mature vegetable compost, four bacterial strains were selected using a lignin-rich medium. 16S ribosomal RNA identification of the isolates showed high score similarity with Pseudomonas spp. for three out of four isolates. Further characterization of growth on mixtures of six selected lignin model compounds (vanillin, vanillate, 4-hydroxybenzoate, p-coumarate, benzoate, and ferulate)
ObjectiveIncreased nuchal translucency originates from disturbed lymphatic development. Abnormal neural crest cell (NCC) migration may be involved in lymphatic development. Because both neuronal and lymphatic development share retinoic acid (RA) as a common factor, this study investigated the involvement of NCCs and RA in specific steps in lymphatic endothelial cell (LEC) differentiation and nucha
Optimum daily light-use efficiency (LUE) and normalized canopy photosynthesis (GEE*) rate, a proxy for LUE, have been derived from eddy covariance CO2 flux measurements obtained at a range of sites located in the mid to high latitudes. These two variables were analyzed with respect to environmental conditions, plant functional types (PFT) and leaf nitrogen concentration, in an attempt to character
Flera vägar till kvalificerad kompetens Flera vägar till kvalificerad kompetens Eftergymnasial utbildning under 2000-talet Innehåll Inledning 3 Utbildningsnivå och privat avkastning 6 Avkastning av högskoleutbildning 7 Högskoleutbildning 10 Examinerade och examina 11 Utbildningens kvalitet 14 Flera vägar till eftergymnasial utbildning 16 Vidareutbildning i högskolan 16 Vidareutbildning genom uppdr
Lunds universitet /Rektor/2014-12-31 Perspektiv från rektor 2009 - 2014 Lunds universitet /Rektor/2014-12-31 Perspektiv på Lunds universitet 2009 - 2014 • Studentbostäder i Lund, militärtält på LTH, soffor, BoPoolen.nu, nya regelverk där LU fått rätt att förhyra studentbostäder för alla studentgrupper och Akademiska hus fått uppdrag att upplåta mark för studentbostäder, nytt byggs och planeras, ”
https://www.lu.se/sites/www.lu.se/files/2014-12-29_perspektiv_fran_rektor_2009_-_20014.pdf - 2026-07-17
