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If the material that you need for your studies or research is not available at any of the libraries at Lund University, you can request an interlibrary loan through the library. This applies for students, researchers, teachers or other employees at the Faculty of Law and you need a valid library card.Please note that we do not order material available at any of the other libraries at Lund Universi

https://www.law.lu.se/library/loans/interlibrary-loans - 2026-04-17

Background Anti-interleukin (IL)-4Rα monoclonal antibodies (mAb) improve lung function and decreasethe number of exacerbations in patients with COPD type (T) 2 inflammation. However, the involvement ofearly innate immune responses underlying these treatment effects is not well known. We sought tounderstand the effect and mechanisms of IL-4Rα mAb treatment on bronchial epithelial cells (BECs) fromCBackgroundAnti-IL-4Rα monoclonal antibodies (mAb) improve lung function and decrease the number of exacerbations in patients with COPD type (T) 2 inflammation. However, the involvement of early innate immune responses underlying these treatment effects is not well known. We sought to understand the effect and mechanisms of IL-4Rα mAb treatment on bronchial epithelial cells from COPD patients under

Mot smartare cellgiftsbehandling: Att förebygga behandlingsresistens vid äggstockscancer Äggstockscancer är den dödligaste gynekologiska cancertypen och kräver alltför många liv eftersom tumörer ofta blir resistenta mot behandling – särskilt mot cisplatin, vårt främsta försvar. För att rädda fler liv måste vi förstå hur denna resistens utvecklas och hur vi kan överlista den. I mitt examensarbete Ovarian cancer is the deadliest gynaecologic malignancy, with most patients diagnosed at an advanced stage and facing poor long-term survival. Resistance to cisplatin-based chemotherapy is a major clinical obstacle, yet its proteomic drivers remain poorly defined. In this study, I applied data-independent acquisition mass spectrometry with DIA-NN data processing to analyse one parental and two cis

In this paper, design and measurements of a fully integrated power amplifier (PA) are presented. The PA consists of two amplifying chains each having a driver and a power stage. A low loss on chip power combiner combines the outputs from two amplifying chains, and also performs impedance transformation and differential to single-ended conversion. To linearize the PA, the driver stage is biased in

BackgroundA novel non-invasive method for generation of pressure volume loops (PV-loops) using brachial blood pressure and cardiovascular magnetic resonance (CMR) imaging has recently been presented and validated (1). The non-invasive nature of this method enables calculation of PV-loops in large patient cohorts previously not feasible due to the need of invasive measurements.PurposeThe purpose of

Popular Abstract in Swedish Människan lever inte bara själv, utan tillsammans med en mängd bakterier som lever i kroppen. Större delen av dessa lever i tjocktarmen. Dessa organismer är viktiga för vår hälsa. De stimulerar immunförsvaret, sänker pH i tarmen och gör det ogynnsamt för sjukdomsframkallande bakterier att växa till. Bakterierna lever i symbios med oss och med varandra. Förändringar i taThe human gut flora is important for our well-being. The gut bacteria are able to degrade and metabolize complex carbohydrates. Examples of such carbohydrates are β-mannans. β-Mannans consist of a backbone of β-1,4-linked mannose units and are present in e.g. the endosperm of legumes such as guar or carob. The composition of the β-mannan varies with the plant source. Carob and guar β-mannans are s

Hemicelluloses account for 25-30% of total wood dry weight. Mannan-based polysaccharides are the major component of softwood hemicelluloses. They are characterized by their β-1,4-glycosidic linked backbone composed of mannose or a combination of mannose and glucose residues. The backbone can be substituted by α-1,6-linked galactose residues. β-mannanases cleave the internal β-1,4-glycosidic bonds

Long-term tobacco smokers with chronic obstructive pulmonary disease (COPD) or chronic bronchitis display an excessive accumulation of neutrophils in the airways; an inflammation that responds poorly to established therapy. Thus, there is a need to identify new molecular targets for the development of effective therapy. Here, we hypothesized that the neutrophil-mobilizing cytokine interleukin (IL)