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Streptomyces species are filamentous bacteria from the phylum Actinobacteria in which cell elongation occurs at the poles of the cell. This differs from many other bacteria like Escherichia coli where cell elongation occurs by insertion of peptidoglycan in the lateral wall. An essential protein for polar growth in Streptomyces is the coil-coiled protein DivIVA. DivIVA has an essential role in orch
Background/purpose Quantitative susceptibility mapping (QSM) is an MRI-based post processing technique to evaluate the magnetic susceptibility, χ, of human tissue using phase data. While brain imaging has been the most common application, other areas have also raised interest. For example, QSM of the articular cartilage of the knee has been suggested as a means to study the degeneration of this ti
In 2021, the Icelandic government stated that Iceland will implement an energy transition plan with the goal of becoming a 100% carbon neutral and fossil free nation by 2040, furthermore, that a doubling in renewable energy production was needed to reach that goal. This led to an upsurge of a discourse among stakeholders and concerned citizens about the future of Iceland. This thesis is an attempt
In this master’s thesis, different options to update the variant rank model used at the University hospital in Lund are presented. The variant rank model filters genetic variants from whole genome sequencing. This is done to identify potential causative variants in patients. Since the knowledge concerning these variants and rare genetic diseases grows rapidly, the model which filters said variants
Streamflow analysis helps us understand the availability of water resources in a region or a river. Accurate and timely streamflow monitoring is essential to improve our understanding of the hydrological cycle. Streamflow information is also necessary for many applications, such as irrigation planning, watershed management, hydropower products, flood control, and integrated water resources managem
Spatial data is an important and necessary ingredient in the disaster management cycle. The preparedness phase requires simulation of disastrous events, identification of disaster management hotspots and creation of hazard- and risk maps. A rapid response in the event of a disaster requires good situational awareness and fast sharing of that knowledge across the community. Further, in the recovery
This paper analyzes if patients’ demand for Direct-to-Consumer Telemedicine (DCT) providers is affected by a change in patient fees. The paper utilizes a natural experiment when the patient fee increased for patients in Region Stockholm using one DCT provider but remained unchanged for other DCT providers. By using DCT visits per month for all other regions as control, the effect on the demand for
The combined global emergence of a sustainable development discourse and Swedish policies requiring municipalities to rapidly build new housing have led Lund to develop Brunnshög. This pioneering megaproject balances urban expansion with high sustainability ambitions. Through the lens of urban political ecology, this thesis aims at analysing Brunnshög’s dominant sustainability narrative as told by
The ability to hear is essential for receiving auditory signals, which serve as warnings and alerts in many situations, including fire evacuation. However, people with hearing impairments may miss out such signals and can be exposed to dangerous situations. This is particularly relevant in scenarios where audible alarms are the primary form of alert, such as in fire scenarios, natural hazards, or
ADHD is a common neurodevelopmental disorder that is defined by a pattern of hyperactivity and/or inattention that negatively affects an individual’s ability to function in everyday life. There are a multitude of challenges in correctly diagnosing ADHD. Symptoms are primarily behavior based and there are not any good biomarkers that can be used to help clinicians to diagnose the disorder correctly
This thesis is inspired by the lack of academic discourse on human rights aspects of human space settlement. It builds on the ever-growing literature on colonizing Mars and the ongoing public debate on the benefits versus disadvantages thereof. Taking on a critical approach, this thesis opens up a conversation on power, universalism, and legitimacy within space exploration, questioning both the on
A prototype of a novel 10B-based neutron detector called the Multi-Grid detector has been constructed, tested and commissioned for the European Spallation Source (ESS). The detector is constructed after the specifications set by the CSPEC instrument at ESS and is therefore called the CSPEC Multi-Grid detector. The detector uses multiple layers of solid coating containing 10B4C on the edges of a vo
The median age for Swedish earth embankment dams is about 60 years. Due to its longevity, one of the major concerns is the internal erosion causing increased seepage through the dam, which ultimately may increases the risk for dam failure. To meet this challenge, there is a need for improved monitoring methods. This in turn requires sensors to be installed inside the earth embankment dams in order
The behaviour and fate of stem cells is governed by the material properties of their surrounding microenvironment. Hence emulating the extracellular matrix poses as an attractive target for tissue engineering endeavours to create a stem cell substrate. Currently, the knowledge of the material properties is mostly limited to the macroscopic level which considerably limits the understanding of tissu
This thesis investigates the volatility structures found in forward-looking fundamental valuations of the Swedish stock index OMXS30. The evaluated data constitutes daily observations of P/E ratios based on twelve months earnings estimates during the period 2009-01-02 until 2018-10-18. The analysis is conducted by applying a GARCH modelling framework to a log-return transformed return series deriv
Ethiopia is the second most populated country on the continent of Africa, with a high density of young people. Its economy remains largely based on agriculture, however, in recent years, slow structural change can be seen. Concurrently, youth education has been on the rise. Due to this phenomenon, the educated youth are now trying to match their skills with current employment opportunities. As a c
This thesis is about the limiting eigenvalue distribution of n × n Toeplitz matrices as n → ∞. The two classical questions we want to answer are: what is the limit set of the eigenvalues, and what is the limiting distribution of the eigenvalues. Our main result is a new approach to calculate the limit set Λ(b) for a Laurent polynomial b, i.e. for banded Toeplitz matrices. The approach is geometric
Perspectives on the role of children and young people in peacebuilding often overlook youth agency. However, the growth of critical theories in peace and conflict studies in the later decades has shone a new light on the need to acknowledge youth as parties to peacebuilding. Through a lens of peace education, this paper analyzes the discourse on youth agency in the context of the largest youth mov
This work is aimed at presenting a design for the proposed HIBEAM beamline which seeks to perform neutron oscillation measurements at the European Spallation Source (ESS). The design is informed by beamline simulations performed with PHITS 3.33 and detector simulations performed with both PHITS and Geant4 11.2. The shielding, consisting of 45 cm of steel and 85 cm of heavy concrete at its thickest
