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Popular Abstract in Swedish Urinvägsinfektioner (UVI) är en av människans vanligaste bakteriella infektioner och drabbar både kvinnor och män. Kvinnor drabbas av UVI under hela sitt vuxna liv, medan UVI incidensen hos män ökar efter 40 – 50 års ålder pga. ökande problematik i urinvägarna med prostataförstoring, m.m. UVI orsakas av ett flertal olika bakteriearter, men tarmbakterien Escherichia coliUrinary tract infections (UTI) are among the most common human infections, and febrile UTI with bacteremia the most severe form. The relation between bacteria and host decides disease severity. The dominating uropathogen is Escherichia coli (E. coli). P fimbriae are the virulence factor of E. coli most clearly associated to severe disease. P fimbriated E. coli predominated in bacteremic febrile UT

Peptide mass fingerprinting (PMF) has over the years become one of the most commonly used tools for high-throughput analysis and identification of proteins. This method is applicable when relatively simple samples have to be analysed and it is commonly used for analysing proteins previously separated by 2-DE. The most common type of instrument used for this approach is the MALDI-TOF that has prove

We consider gamma-ray bursts (GRBs) produced by the merger of a massive white dwarf with a neutron star. We show that these are likely to produce long-duration GRBs, in some cases definitely without an accompanying supernova, as observed recently. This class of burst would have a strong correlation with star formation, and occur close to the host galaxy. However, rare members of the class need not

The distribution of a semiflexible chain in the volume of two interconnected spherical cavities of equal size has been investigated by using Monte Carlo simulations. The chain possessed an extension exceeding that of the cavity, leading to large probabilities of translocated states despite the entropic penalty of passing the narrow passage. Furthermore, an asymmetric state with unequal subchain le

HAMLET is a protein-lipid complex that selectively kills tumor cells. In this thesis, we identified new mechanisms, whereby HAMLET initiates and executes tumor cell death. HAMLET targets several cellular compartments ranging from the plasma membrane to the nucleus. HAMLET rapidly binds to the plasma membrane of tumor cells and the resulting changes in membrane shape and lipid composition activate

Varicose veins (VVs) have been associated with venous thromboembolism (VTE), but whether these diseases share familial susceptibility has not been determined. This nationwide study aimed to determine whether VTE shares familial susceptibility with VVs.

Popular Abstract in Swedish ”Practice variation” I den kliniska vardagen ser man ofta slående variationer i handläggningsrutiner mellan läkare och vårdcentraler utan att detta kan förklaras av skillnader i sjuklighet hos patienterna. Dessa oförklarade skillnader benämns ”practice variation” och beror på lokalt förankrade rutiner ofta etablerade sedan länge. De är sällan vetenskapligt underbyggda u

Practically all natural daytime light at the Earth’s surface originates in the Sun. The fluence rate, as well as spectral and directional distributions are modified by the gases, clouds and aerosols in the atmosphere in a way which depends on time and place, and also by vegetation, snow, and other ground-cover. A special section in this chapter is devoted to ultraviolet radiation.

Wearer trials with human subjects were included in the Subzero project in order to validate the manikins' data against practice. Physiological tests of the project were aimed to study hu-man subjects at thermal comfort or being slightly warm in cold: 0, -10, -25 and wind-chill temperature –50 ºC. Wind-chill temperature –50 was achieved by combination of 2 tempera-tures and wind velocities: -40 ºC

This paper reviews means for fatigue damage rates estimation using Laplace distributed multiaxial loads. The model is suitable for description of stresses containing transients of random amplitudes and locations. Explicit formulas for computing the expected value of rainflow damage index as a function of excess kurtosis are given for correlated loads. A Laplace model is used to describe variabilit