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BACKGROUND: With the scale-up of antiretroviral therapy (ART), monitoring programme performance is needed to maximize ART efficacy and limit HIV drug resistance (HIVDR).METHODS: We implemented a WHO HIVDR prospective survey protocol at three treatment centers between 2012 and 2013. Data were abstracted from patient records at ART start (T1) and after 12 months (T2). Genotyping was performed in the
The aim was to describe milk feeding patterns and first weaning foods during the first year of life in a large prospective birth cohort of infants with increased genetic risk for Type 1 diabetes (T1D) recruited in 4 different countries: the United States, Finland, Germany, and Sweden. All enrolled children with dietary information (n = 8,673) were included in the analyses; 1,307 (15%) children who
CD4+ T cells subsets have a wide range of important helper and regulatory functions in the immune system. Several studies have specifically suggested that circulating effector CD4+ T cells may play a direct role in control of HIV replication through cytolytic activity or autocrine β-chemokine production. However, it remains unclear whether effector CD4+ T cells expressing cytolytic molecules and β
This paper discusses various observations on beam-induced and cosmic-ray backgrounds in the ATLAS detector during the LHC 2012 proton-proton run. Building on published results based on 2011 data, the correlations between background and residual pressure of the beam vacuum are revisited. Ghost charge evolution over 2012 and its role for backgrounds are evaluated. New methods to monitor ghost charge
Over the last few decades, the African Sahel has become thefocus of many studies regarding vegetation dynamics and theirrelationships with climate and people. This is because rainfalllimits the production of biomass in the region, a resource onwhich people are directly dependent for their livelihoods. In thisstudy, we utilized a remote-sensing approach to answering thefollowing two questions: (1)
During the Cold War, along with the Americanization of its popular culture, Finland was also heavily exposed to Soviet ideological influences, including in relation to notions of desirable femininity. From the late 1960s onwards, Soviet influences can be seen in Finnish public discourses on fashion and decorative femininity. Soviet ideals are also reflected in the emphasis on gender neutrality and
We have reconstructed the distribution of extraterrestrial chrome spinels in a marine limestone section across the Frasnian–Famennian stratotype section at Coumiac in southern France, providing the first insights on the types of micrometeorites and meteorites that fell on Earth at this time. The data can test whether the small cluster of roughly coeval, large impact structures is related to an ast
An important component of the carbon cycle is the lateral flow of dissolved organic carbon (DOC) from terrestrial ecosystems to streams and rivers. The fate of this carbon depends very much on the bioavailability of DOC (BDOC), which may determine whether DOC is returned to the atmosphere as CO2 or deposited in sediments. This study focuses on the linkages between stream DOC composition, optical c
The high variability in the hydrological regime of the Eastern Hydrological Region (EHR) of Northeast Brazil often results in floods and droughts, leading to serious socio-economic issues. Therefore, this work aimed to investigate connections between spatiotemporal hydrological variability of the EHR and large-scale climate phenomena. Multivariate statistical techniques were applied to relate clim
BackgroundMany countries and regions undergo structural changes that intent to improve the effectiveness and quality of care. Until 2007, the municipalities, counties, hospitals and pharmacies shared the smoking cessation activities almost equally in Denmark. Among others, the Danish Healthcare Reform 2007 intended to add responsibility for smoking cessation intervention at county level to the mu
Capsule: Foraging behaviour in the Razorbill Alca torda during breeding was similar to that found elsewhere, aside from dive shape. Aims: To investigate the foraging behaviour of Razorbills during the breeding season at the largest colony in the central Baltic Sea. Methods: A combination of global positioning system (GPS) and time-depth recorder (TDR) devices were used on Razorbills breeding on th
Two imaging techniques are used to investigate the interaction between developed combustion from earlier injections and partially oxidized fuel (POF) ofa subsequent injection. The latter is visualized by using planar laser induced fluorescence (PLIF) of formaldehyde and poly-cyclic aromatic hydrocarbons. High speed imaging captures the natural luminescence (NL) of the prevailing combustion. Three
This paper investigates the outcome of the efforts to economically catch up during theso-called development era in French-speaking West Africa. An attempt is made tomeasure and discuss key elements of social capability over the period 1930–1980 inCôte d’Ivoire and Senegal following Moses Abramovitz’interpretation of socialcapability. The paper distinguishes between four elements of social capabili
One of the greatest challenges for the world today is the reduction of greenhouse gas emissions. As buildings contribute to almost a quarter of the greenhouse gas emissions worldwide, reducing the energy use of the existing building stock is an important measure for climate change mitigation. In order to increase the renovation pace, there is a need for a comprehensive technicaldocumentation that
A possible role for infections of the pregnant mother in the development of childhood acute leukemias and lymphomas has been suggested. However, no specific infectious agent has been identified. Offspring of 74,000 mothers who had serum samples taken during pregnancy and stored in a large-scale biobank were followed up to the age of 15 years (750,000 person years) through over-generation linkages
To keep balance when standing or walking on a surface inclined in the roll plane, the cat modifies its body configuration so that the functional length of its right and left limbs becomes different. The aim of the present study was to assess the motor cortex participation in the generation of this left/right asymmetry. We recorded the activity of fore- and hindlimb-related pyramidal tract neurons
