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JW-MDS#130009 1..9 Study of the Antidyskinetic Effect of Eltoprazine in Animal Models of Levodopa-Induced Dyskinesia Erwan Bezard, PhD,1,2,3 Elisabetta Tronci, PhD,4,5 Elsa Y. Pioli, PhD,6 Qin Li, PhD,3,6 Gregory Porras, PhD,6 Anders Bj€orklund, MD,5 and Manolo Carta, PhD4,5* 1Institute for Neurodegenerative Diseases, Bordeaux University, Bordeaux, France 2Institute for Neurodegenerative Diseases,

https://www.neurobiology.lu.se/sites/neurobiology.lu.se/files/publication_in_mov_disord.pdf - 2025-11-19

As more and more companies are realizing the importance to integrate sustainability with their economic prosperity development, Triple Bottom Line functions as companies' Polaris to guide them to incorporate "People, Planet" considerations into their "Profit" seeking goal. Corporate social responsibility initiatives are adopted by many companies. Among them, Cause Related M

Under de senaste 10 åren har ökningen av export från EU av farligt och ”ofarligt” avfall varit betydande. Rapporter visar att en övervägande del av EU:s el-avfall och elektroniska avfall exporteras till Asien och Afrika. ”Ofarligt” avfall, såsom plast och papper, transporteras främst till Asien och i synnerhet till Kina. I dessa länder finns emellertid ofta inte kapaciteten och tekniken att hanter

Ett för miljörätten tidigt uppkommet styrmedel som idag hyllas är miljökonsekvensbeskrivningen. Flertalet länder har infört MKB i sin lagstiftning och det har utformats internationella bestämmelser för gränsöverskridande miljöpåverkan. Även inom klimatregimen finns reglering för projekt i CDM systemet. I detta arbete har Sveriges CDM projekt studerats för att fastställa syfte med MKB inom CDM systA respected and early invention among the means of control in environmental law is the impact assessment. Numerous countries have implemented EIA in their national legislation and international treaties regulates transboundary environmental impacts. UNFCCC also contains EIA regulations for projects within the clean development mechanism. In this study Swedish projects are examined to establish the

Popular Abstract in Swedish POPULÄRVETENSKAPLIG SAMMANFATTNING PÅ SVENSKA Kadmium är en giftig metall vilken finns i mat som vi rekommenderas äta mycket av, exempelvis sädesprodukter, grönsaker och skaldjur. Våra matjordar är kontaminerade med kadmium och föroreningen kommer att kvarstå under mycket lång tid framöver. Kadmium skadar framförallt njurarna och skelettet och kan antagligen även orsaAbstract: Cadmium (Cd) is ubiquitous in the environment. Human exposure in non-smokers occurs mainly via intake of healthy food like vegetables, cereals, and shellfish. Adverse health effects on kidney and bone at low-level environmental Cd exposure are well-documented in adults. There is considerable inter-individual variation in both metabolism (toxicokinetics) and toxicity (toxicodynamics) of C

Sri Lanka is a small island in the Indian Ocean with a population of 19.5 million. UN (2005), &lt&semichttp://news.bbc.co.uk/2/hi/south_asia/country_profiles/1168427.stm&gt&semic, visited on 13th December 2005. History witnesseth of the Yakka &amp&semic Naga tribes ('Gothras') and the Nittevo The Nittevo are said to have been a dwarfish race of men who lived in the

Version 3 av ecoinvent är den första databasen att erbjuda möjligheten att koppla samman livscykelinventeringar (LCI) utefter olika länkningsalgoritmer. Genom dessa länkningsalgoritmer tar ecoinvent nu fram bakgrundslivscykelinventeringar med både medeldata och långsiktig marginaldata (t.ex. över elmarknader i olika länder). Idealt sett representerar långsiktig marginaldata över elmarknader den ytVersion 3 of the ecoinvent database is the first background database to offer the possibility to link life cycle inventories (LCI) according to different linking algorithms. Using those algorithms, ecoinvent now provides both average and long-term, marginal background LCI data, (e.g. for electricity markets for different countries). Long-term, marginal data for electricity markets ideally represen

Popular Abstract in Swedish Diabetes är en grupp sjukdomar som alla kännetecknas av en förhöjd nivå av sockerarten glukos i blodet. Antalet individer som drabbas av diabetes ökar hela tiden, en utveckling som ses över hela världen. Bara i Sverige har drygt 5% av befolkningen diagnosen diabetes, motsvarande 484.400 personer i åldern 20-79 år. Typ 2 diabetes är den vanligaste formen av diabetes, ochThe incidence of diabetes is increasing worldwide, with the most prevalent form being type 2 diabetes. Two fundamental processes contribute to the development of type 2 diabetes: insulin resistance in target organs and insufficient insulin secretion from the pancreatic beta-cells. The aim of this thesis was to explore the role of DNA methylation and common genetic variation on glucose metabolism a

Popular Abstract in Swedish Nästan en miljon nya fall av magsäckscancer diagnostiseras årligen världen över. Även om frekvensen har fallit dramatiskt de senaste åren så är magsäckscancern fortfarande den näst vanligaste orsaken till död i cancer sett ur ett världsperspektiv. Den geografiska variationen av denna cancertyp är anmärkningsvärd med den högsta förekomsten i asiatiska länder såsom Japan,

In hydrological models for water resources management and planning, the model output or design quantities are functions of the input data and a number of parameters that are essentially stochastic processes or random variables. The task of uncertainty analysis is to estimate the uncertainty characteristics of the model output in terms of the uncertainties in the input, model parameters and initial

Background: The frequent emergence of the re-positive patients with COVID-19 is a potential threat worldwide. This study aimed to describe data from admission to follow-up for patients with COVID-19 and analyze the possible causes for re-positive nucleic acid tests to provide more scientific basis for reducing the numbers of re-positive patients after discharge. Methods: We retrospectively recorde

Spatial downscaling is an effective way to obtain precipitation with sufficient spatial details. The performance of downscaling is typically determined by the empirical statistical relationships between precipitation and the used auxiliary variables. In this study, we conducted a comprehensive comparison of five empirical statistical methods for spatial downscaling of GPM IMERG V06B monthly and an

Based on trend, cross-cutting relationships and U-Pb dating, Precambrian mafic dykes in the Singhbhum craton, earlier collectively identified as ‘Newer Dolerite Swarm’ have been separated into seven distinct swarms, which are thought to be the plumbing systems for Large Igneous Provinces (LIPs). These Singhbhum swarms range in age from ∼2.80 Ga to ∼1.76 Ga, and include the ∼2.80 Ga NE-SW trending

Version 3 av ecoinvent är den första databasen att erbjuda möjligheten att koppla samman livscykelinventeringar (LCI) utefter olika länkningsalgoritmer. Genom dessa länkningsalgoritmer tar ecoinvent nu fram bakgrundslivscykelinventeringar med både medeldata och långsiktig marginaldata (t.ex. över elmarknader i olika länder). Idealt sett representerar långsiktig marginaldata över elmarknader den ytVersion 3 of the ecoinvent database is the first background database to offer the possibility to link life cycle inventories (LCI) according to different linking algorithms. Using those algorithms, ecoinvent now provides both average and long-term, marginal background LCI data, (e.g. for electricity markets for different countries). Long-term, marginal data for electricity markets ideally represen

This Ph.D. submission deals with contemporary demonstration culture and political activism, seen as performance through performance. It consists of both a practical and a theoretical part. These are intertwined on various levels of the project. My submission, however, is made up of the two following parts: 1: A textual part, divided into 8 parts. Each part contains a script, an analysis and a nu

Popular Abstract in Swedish Epidemiologi är den vetenskap som studerar sjukdomars förekomst och spridning och hur detta varierar över tiden, mellan geografiska områden och mellan grupper av individer definierade i olika termer. I Malmö finns det mycket goda möjligheter att göra epidemiologiska studier av slaganfall (stroke). Dels finns ett register som följt strokeinsjuknandet sedan 1989. Dels harThe present thesis explored the epidemiology of stroke in Malmö, Sweden, an urban population of approximately 250000 inhabitants. Incidence of stroke in Malmö has been monitored since 1989. The National census investigation in 1990 was used to get information about the background population in the city. Previous studies of the seasonal and weekday variations in incidence of stroke have shown inco

OBJECTIVE To investigate the primary pharmacology of fesoterodine (a novel antimuscarinic drug developed for treating overactive bladder) and SPM 7605 (its active metabolite, considered to be the main pharmacologically active principle of fesoterodine in man) against human muscarinic receptor subtypes, and to investigate in vitro and in vivo functional activity of these agents on the rat bladder c